Advanced Materials, EarlyView.A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li +7 more
wiley +1 more source
Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function. [PDF]
, 2019 Normal synapse formation is fundamental to brain function. We show here that an apical-basal polarity (A-BP) protein, Lgl1, is present in the postsynaptic density and negatively regulates glutamatergic synapse numbers by antagonizing the atypical protein
Cheng, Hongqiang +12 more
core +1 more source
Coincidence detection in single dendritic spines mediated by calcium release [PDF]
, 2000 Samuel S.‐H. Wang +2 more
openalex +1 more source
Advanced Materials, EarlyView.This study reveals how LiBH4 doping in argyrodite‐type Li6PS5Cl solid‐state electrolyte improves electrochemical stability by forming a tri‐layer SEI based predominately on Li3P/LiBH4/Li2S that promotes ion transport and blocks electrons. In situ XPS and TOF‐SIMS show thinner SEI, enhanced Li electrodeposition, and better interfacial wetting compared ...
Yixian Wang +14 more
wiley +1 more source
Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex [PDF]
, 2000 Miguel Ángel Rodríguez +6 more
openalex +1 more source
Hardware Implementation of On‐Chip Hebbian Learning Through Integrated Neuromorphic Architecture
Advanced Materials, EarlyView.This work presents a neuromorphic hardware platform that integrates presynaptic transistors, threshold switching neurons, and adaptive feedback synapses. The architecture enables on‐chip Hebbian learning through correlation‐based weight updates without external training circuits.
Seonkwon Kim +6 more
wiley +1 more source
Remodeling Dendritic Spines of Dentate Granule Cells in Temporal Lobe Epilepsy Patients and the Rat Pilocarpine Model [PDF]
, 2000 Masako Isokawa
openalex +1 more source
Bioinspired Smart Nanogels for Rapid Blue Laser‐Activated Hemostasis in Gastrointestinal Bleeding
Advanced Materials, EarlyView.Waxberry‐inspired branched‐silica nanogel can swiftly stop bleeding upon blue laser endoscopy for gastrointestinal hemostasis in the esophagus, stomach, and duodenum of mini‐pigs. Abstract Gastrointestinal bleeding (GIB) is a critical condition that requires rapid and effective intervention.
Ruijue Dan +12 more
wiley +1 more source
Cocaine self‐administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex [PDF]
, 2001 Terry E. Robinson +3 more
openalex +2 more sources