Results 221 to 230 of about 70,784 (294)

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

Spot Spine, a freely available ImageJ plugin for 3D detection and morphological analysis of dendritic spines. [PDF]

F1000Res
Gilles JF, Mailly P, Ferreira T, Boudier T, Heck N.   +4 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Expression of Concern: A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic Tau mouse model of Alzheimer disease. [PDF]

Hum Mol Genet
europepmc   +1 more source

Disruption of Extracellular Signal-Regulated Kinase Partially Mediates Neonatal Isoflurane Anesthesia-Induced Changes in Dendritic Spines and Cognitive Function in Juvenile Mice. [PDF]

Int J Mol Sci
Agarwal S, Bochkova J, Mohamed MK, Schaefer ML, Zhou A, Skinner J, Johns RA.   +6 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

TAF15 downregulation contributes to the benefits of physical training on dendritic spines and working memory in aged mice. [PDF]

Aging Cell
He Y, Liu B, Yang FY, Yang Q, Xu B, Liu L, Chen Y.   +6 more
europepmc   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Simultaneous Construction of Hydrophobic Environment and Optimized Ion Channels in V2O5 for Zinc Ion Batteries

Carbon Energy, EarlyView.
With the preinsertion of hexamethylenebisammonium (HMA2+), the thermodynamic stability of V2O5 is improved, and the kinetics of electrochemical reaction are enhanced, benefiting from the pillar effect, hydrophobicity, and electrostatic shielding of HMA2+.
Leilei Sun, Hanwei Hu, Guosheng Duan, Bin Luo, Sinan Zheng, Zhean Bao, Dinghao Chen, Maojun Zhou, Kun Zhang, Yang Wang, Jingyun Huang, Zhizhen Ye   +11 more
wiley   +1 more source

Longevity, enhanced memory, and altered density of dendritic spines in hippocampal CA3 and dentate gyrus after hemizygous deletion of Pde2a in mice. [PDF]

Neuropsychopharmacology
Baumgärtel K, Broadbent NJ, Su H, Masatsugu B, Maruyama KP, Johnson RW, Green AL, Hornberger DK, Petroski R, Scott R, Peters M.   +10 more
europepmc   +1 more source