Results 221 to 230 of about 553,059 (371)
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk+8 more
wiley +1 more source
Endoplasmic reticulum: Regulator of structural potentiation of dendritic spines. [PDF]
Dittmer PJ, Dell'Acqua ML.
europepmc +1 more source
Cadherin Regulates Dendritic Spine Morphogenesis [PDF]
Hideru Togashi+5 more
openalex +1 more source
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui+19 more
wiley +1 more source
VSOT: volume-surface optimization for accurate ultrastructure analysis of dendritic spines. [PDF]
Lyu B, Wang J, Risher WC, Yu G.
europepmc +1 more source
Formation of Dendritic Spines with GABAergic Synapses Induced by Whisker Stimulation in Adult Mice [PDF]
Graham Knott+3 more
openalex +1 more source
Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu+15 more
wiley +1 more source
Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou+14 more
wiley +1 more source