Results 281 to 290 of about 553,059 (371)

Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain Injury

Advanced Science, EarlyView.
This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee   +9 more
wiley   +1 more source

State-Dependent Calcium Signaling in Dendritic Spines of Striatal Medium Spiny Neurons [PDF]

, 2004
Adam G. Carter, Bernardo L. Sabatini
openalex   +1 more source

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

Advanced Science, EarlyView.
Zheng et al. designed a tumor microenvironment (TME)‐responsive nanosystem, HmBMH@MSA‐2. It targets tumors, releases MSA‐2 and Mn ions in high glutathione (GSH) conditions, achieving STING agonist delivery and MRI. The nanosystem promotes chemodynamic therapy (CDT), achieves radiosensitization, and activates the cGAS‐STING pathway.
Yinfei Zheng, Shuting Zheng, Yushu Liao, Zede Wu, Chenxi He, Qiuyu Li, Honglei Hu, Zheyu Shen, Yikai Xu, Chenggong Yan, Bingxia Zhao, Meirong Hou   +11 more
wiley   +1 more source

A High‐Performance Garnet‐Based All‐Solid‐State Battery Fabricated Through Room‐Temperature Ultrasonic Welding

Advanced Science, EarlyView.
A room‐temperature ultrasonic treatment enhances the LiMg/LLZO interface, where the Mg framework and in situ formed Li2O/MgO interphase enable a record 4.45 mA cm−2 CCD and a stable cycling for over 1000 h at 1 mA cm−2. Combined with a fluorinated cathode interface, the ASSB delivers 153 mAh g−1 at 0.5 C with 90% capacity retention after 200 cycles ...
Tianlu Pang, Shufen Wu, Han Wu, Xiaobao Li, Yande Li, LiTao Yu, Hui Zhang, Yong Han, Zhi Guo, Nian Zhang   +9 more
wiley   +1 more source

Cognitive integrity in Non-Demented Individuals with Alzheimer's Neuropathology is associated with preservation and remodeling of dendritic spines. [PDF]

Alzheimers Dement
Guptarak J, Scaduto P, Tumurbaatar B, Zhang WR, Jupiter D, Taglialatela G, Fracassi A.   +6 more
europepmc   +1 more source

GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Neurite Outgrowth and Dendritic Spine Formation [PDF]

, 2004
Brad A. Bryan, Vikas Kumar, Lewis J. Stafford, Yi Cai, Gangyi Wu, Mingyao Liu   +5 more
openalex   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source

Homeostatic Shrinkage of Dendritic Spines Requires Melatonin Type 3 Receptor Activation During Sleep. [PDF]

Adv Sci (Weinh)
Li S, Li X, Lu M, Chen Q, Yao D, Yu X, Li Z, Ge WP, Wang N, Jin J, Wang Y, Liao Y, Luo F, Yan J, Chen X, Jiang C, Yue F, Gao D, Tang X, Guo H, Wang Y, Chen X, Xia J, Xu M, Ren S, He C, Hu Z.   +26 more
europepmc   +1 more source

A critical time window for dopamine actions on the structural plasticity of dendritic spines

Science, 2014
Sho Yagishita, Akiko Hayashi-Takagi, G. Ellis‐Davies, H. Urakubo, Shin Ishii, H. Kasai   +5 more
semanticscholar   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source