Results 1 to 10 of about 68,197 (100)

Phenotype and functionality of follicular helper T cells in patients with acute dengue infection

Journal of Biomedical Science, 2020
Background The association of functionality and phenotype of follicular helper T cells (Tfh) with dengue virus (DENV) specific antibody responses and clinical disease severity has not been well studied.
Ayesha Wijesinghe, Jayani Gamage, Hemantha Goonewardena, Laksiri Gomes, Deshni Jayathilaka, Dulharie T. Wijeratne, Ruklanthi de Alwis, Chandima Jeewandara, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie Neelika Malavige   +10 more
doaj   +1 more source

Decadal Change in Seroprevalence of Chikungunya Virus Infection in Pune City, India

Viruses, 2022
Chikungunya virus (CHIKV) is an arthropod-borne virus capable of causing large outbreaks. We aimed to determine the decadal change in the extent of chikungunya virus infection from 2009 to 2019. We implemented a prospective cross-sectional survey in Pune
Shilpa Jagatram Tomar, Kalichamy Alagarasu, Ashwini More, Manasi Nadkarni, Rupali Bachal, Minal Bote, Jayashri Patil, Vasanthy Venkatesh, Deepti Parashar, Babasaheb Vishwanath Tandale   +9 more
doaj   +1 more source

Effect of Zinc(II)-2,4,5-triphenyl-1H-imidazole Complex Against Replication DENV-2 in Vero Cell

Indonesian Journal of Tropical and Infectious Disease, 2020
Dengue virus (DENV) is a significant pathogen emerging worldwide as a cause of infectious disease. DENVs are transmitted to humans through female mosquitoes from Aedes aegypti and Aedes albopictus species. Indonesia is one of the largest countries in the
Teguh Hari Sucipto, Aswandi Wibrianto, Fahimah Martak, Siti Churrotin, Ilham Harlan Amarullah, Harsasi Setyawati, Puspa Wardhani, Aryati Aryati, Soegeng Soegijanto   +8 more
doaj   +1 more source

Risk Factors for Elevated Serum Lipopolysaccharide in Acute Dengue and Association with Clinical Disease Severity

Tropical Medicine and Infectious Disease, 2020
Although serum lipopolysaccharide (LPS) was shown to associate with development of severe dengue, the reasons for high LPS and its subsequent involvement in disease pathogenesis are not known.
N. L. Ajantha Shyamali, Sameera D. Mahapatuna, Laksiri Gomes, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie Neelika Malavige   +5 more
doaj   +1 more source

ANTI-DENGUE TYPE 2 VIRUS ACTIVITIES OF ZINC (II) COMPLEX COMPOUNDS WITH 2-(2,4 -DIHYDROXYPHENYL)-3,5,7-TRIHYDROXYCROMEN-4-ONE LIGANDS IN VERO CELLS

Indonesian Journal of Tropical and Infectious Disease, 2019
Dengue virus (DENV) is a disease that is transmitted through Aedes aegypti and Aedes albopictus mosquitoes, and is spread in tropical and sub-tropical regions.
Teguh Hari Sucipto, Harsasi Setyawati, Siti Churrotin, Ilham Harlan Amarullah, Sri Sumarsih, Puspa Wardhani, Aryati Aryati, Soegeng Soegijanto   +7 more
doaj   +1 more source

DIFFERENCES OF UNIVERSAL AND MULTIPLEX PRIMER FOR DETECTION OF DENGUE VIRUS FROM PATIENTS SUSPECTED DENGUE HEMORRHAGIC FEVER (DHF) IN SURABAYA

Indonesian Journal of Tropical and Infectious Disease, 2015
Dengue Hemorrhagic Fever (DHF) is a global health problem in tropical and subtropical regions, as well as endemic in110 countries around the world. Indonesia is one of the largest countries in the region of endemic dengue.
Arif Ansori, Teguh Sucipto, Pemta Deka, Nur Ahwanah, Siti Churrotin, Tomohiro Kotaki, Soegeng Soegijanto   +6 more
doaj   +1 more source

SARS-CoV-2 neutralizing antibodies in patients with varying severity of acute COVID-19 illness

Scientific Reports, 2021
In order to support vaccine development, and to aid convalescent plasma therapy, it would be important to understand the kinetics, timing and persistence of SARS-CoV-2 neutralizing antibodies (NAbs), and their association with clinical disease severity ...
Chandima Jeewandara, Deshni Jayathilaka, Laksiri Gomes, Ananda Wijewickrama, Eranga Narangoda, Damayanthi Idampitiya, Dinuka Guruge, Ruwan Wijayamuni, Suranga Manilgama, Graham S. Ogg, Chee Wah Tan, Lin-Fa Wang, Gathsaurie Neelika Malavige   +12 more
doaj   +1 more source

Oligonucleotide-Based Approaches to Inhibit Dengue Virus Replication

Molecules, 2021
Dengue fever is one of the most common viral infections affecting humans. It is an expanding public health problem, particularly in tropical and subtropical regions.
Kingshuk Panda, Kalichamy Alagarasu, Deepti Parashar   +2 more
doaj   +1 more source

Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection

Nature Communications, 2018
The antibody response during infection with dengue virus is a key component involved in the pathogenesis during secondary infection. Here the authors show antibodies targeting NS1 and the epitopes targeted can be associated with disease severity during ...
Deshni Jayathilaka, Laksiri Gomes, Chandima Jeewandara, Geethal. S. Bandara Jayarathna, Dhanushka Herath, Pathum Asela Perera, Samitha Fernando, Ananda Wijewickrama, Clare S. Hardman, Graham S. Ogg, Gathsaurie Neelika Malavige   +10 more
doaj   +1 more source

Seroprevalence and incidence of primary dengue infections among children in a rural region of Maharashtra, Western India

BMC Infectious Diseases, 2019
Background Dengue infections have become a huge threat to public health systems in developing countries. Data on seroprevalence and incidence of dengue infections are lacking from rural regions of India.
Paresh S. Shah, Kalichamy Alagarasu, Shivaji Karad, Avinash Deoshatwar, Santosh M. Jadhav, Tushar Raut, Anand Singh, Cecilia Dayaraj, Vasant S. Padbidri   +8 more
doaj   +1 more source