Results 31 to 40 of about 371,111 (371)

Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy

New England Journal of Medicine, 2018
Background In efficacy trials of a tetravalent dengue vaccine (CYD‐TDV), excess hospitalizations for dengue were observed among vaccine recipients 2 to 5 years of age.
S. Sridhar, Alexander Luedtke, E. Langevin, M. Zhu, M. Bonaparte, Tifany Machabert, S. Savarino, B. Zambrano, A. Moureau, A. Khromava, Z. Moodie, T. Westling, C. Mascareñas, Carina Frago, M. Cortés, D. Chansinghakul, F. Noriega, A. Bouckenooghe, Josh Chen, S. Ng, P. Gilbert, S. Gurunathan, C. Diazgranados   +22 more
semanticscholar   +1 more source

The Global Expansion of Dengue: How Aedes aegypti Mosquitoes Enabled the First Pandemic Arbovirus.

Annual Review of Entomology, 2020
Dengue is an emerging viral disease principally transmitted by the Aedes (Stegomyia) aegypti mosquito. It is one of the fastest-growing global infectious diseases, with 100-400 million new infections a year, and is now entrenched in a growing number of ...
O. Brady, Simon Iain Hay
semanticscholar   +1 more source

Intrahost Selection Pressures Drive Rapid Dengue Virus Microevolution in Acute Human Infections. [PDF]

, 2017
Dengue, caused by four dengue virus serotypes (DENV-1 to DENV-4), is a highly prevalent mosquito-borne viral disease in humans. Yet, selection pressures driving DENV microevolution within human hosts (intrahost) remain unknown. We employed a whole-genome
Balmaseda, Angel, Eswarappa, Meghana, Harris, Eva, Montoya, Magelda, Parameswaran, Poornima, Trivedi, Surbhi Bharat, Wang, Chunling   +6 more
core   +1 more source

Antibody-dependent enhancement of severe dengue disease in humans

Science, 2017
Too much or too little—better than some Dengue fever is caused by a mosquito-transmitted flavivirus resembling Zika virus. Both viruses can cause severe diseases in humans with catastrophic sequelae.
L. Katzelnick, L. Gresh, M. E. Halloran, J. Mercado, G. Kuan, A. Gordon, Á. Balmaseda, E. Harris   +7 more
semanticscholar   +1 more source

Risk Factors for Elevated Serum Lipopolysaccharide in Acute Dengue and Association with Clinical Disease Severity

Tropical Medicine and Infectious Disease, 2020
Although serum lipopolysaccharide (LPS) was shown to associate with development of severe dengue, the reasons for high LPS and its subsequent involvement in disease pathogenesis are not known.
N. L. Ajantha Shyamali, Sameera D. Mahapatuna, Laksiri Gomes, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie Neelika Malavige   +5 more
doaj   +1 more source

The effects of weather and climate change on dengue [PDF]

, 2013
There is much uncertainty about the future impact of climate change on vector-borne diseases. Such uncertainty reflects the difficulties in modelling the complex interactions between disease, climatic and socioeconomic determinants.
Colón-González, Felipe J., Fezzi, Carlo, Hunter, Paul R., Lake, Iain R.   +3 more
core   +2 more sources

Dengue and dengue hemorrhagic fever.

, 2014
Continued geographic expansion of dengue viruses and their mosquito vectors has seen the magnitude and frequency of epidemic dengue/dengue hemorrhagic fever (DF/DHF) increase dramatically.
D. Gubler, E. Ooi, S. Vasudevan, J. Farrar   +3 more
semanticscholar   +1 more source

Potential for using climate forecasts in spatio-temporal prediction of dengue fever incidence in Malaysia submitted [PDF]

, 2015
Dengue fever is a viral infection transmitted by the bite of female Aedes aegypti mosquitoes. It is estimated that nearly 40% of the world’s population is now at risk from Dengue in over 100 endemic countries including Malaysia.
Harun, Amran, Hasan, Haslinda, Zainal Rashid, Mohd Shaffran   +2 more
core   +3 more sources

Zika virus infection enhances future risk of severe dengue disease

Science, 2020
Double whammy Dengue and Zika virus epidemics have been lapping each other around the globe. These are closely related mosquito-borne viruses with about 40% homology within the envelope protein.
L. Katzelnick, César Narvaez, Sonia Arguello, Brenda Lopez Mercado, Damaris Collado, Oscarlett Ampie, Douglas Elizondo, Tatiana Miranda, Fausto Bustos Carillo, J. Mercado, Krista Latta, Amy J Schiller, Bruno Segovia-Chumbez, S. Ojeda, N. Sanchez, M. Plazaola, J. Coloma, M. Halloran, L. Premkumar, A. Gordon, Federico Narvaez, A. D. de Silva, G. Kuan, Á. Balmaseda, E. Harris   +24 more
semanticscholar   +1 more source

ANTI-DENGUE TYPE 2 VIRUS ACTIVITIES OF ZINC (II) COMPLEX COMPOUNDS WITH 2-(2,4 -DIHYDROXYPHENYL)-3,5,7-TRIHYDROXYCROMEN-4-ONE LIGANDS IN VERO CELLS

Indonesian Journal of Tropical and Infectious Disease, 2019
Dengue virus (DENV) is a disease that is transmitted through Aedes aegypti and Aedes albopictus mosquitoes, and is spread in tropical and sub-tropical regions.
Teguh Hari Sucipto, Harsasi Setyawati, Siti Churrotin, Ilham Harlan Amarullah, Sri Sumarsih, Puspa Wardhani, Aryati Aryati, Soegeng Soegijanto   +7 more
doaj   +1 more source