Results 31 to 40 of about 146,661 (289)

Identification of Novel Candidate CD8+ T Cell Epitopes of the SARS-CoV2 with Homology to Other Seasonal Coronaviruses

open access: yesViruses, 2021
Cross-reactive T cell immunity to seasonal coronaviruses (HCoVs) may lead to immunopathology or protection during SARS-CoV2 infection. To understand the influence of cross-reactive T cell responses, we used IEDB (Immune epitope database) and NetMHCpan ...
Pradeep Darshana Pushpakumara   +5 more
doaj   +1 more source

Hemorrhagic encephalopathy in dengue shock syndrome: a case report

open access: yesBrazilian Journal of Infectious Diseases
Dengue fever is the most important arboviral infection in the world, with an estimated 100 million cases per year and 2.5 billion people at risk.
Luiz José de Souza   +7 more
doaj   +1 more source

Drug repurposing approach against chikungunya virus: an in vitro and in silico study

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes. There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing approach has emerged as a novel concept to find alternative uses of therapeutics to
Bhagyashri Kasabe   +8 more
doaj   +1 more source

The impact of dengue on liver function as evaluated by aminotransferase levels

open access: yesBrazilian Journal of Infectious Diseases
The objective of this study was to evaluate the impact of dengue virus infection on liver function by measuring aminotransferase in blood samples from patients serologically diagnosed by according to two MAC-ELISA protocols.
Luiz José de Souza   +7 more
doaj   +1 more source

Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1,585 cases

open access: yesBrazilian Journal of Infectious Diseases
INTRODUCTION: Type 3 dengue virus caused an extensive epidemic in the state of Rio de Janeiro in summer 2002. In some of the patients, it was found in an atypical form with increased aminotransferase levels and acute hepatitis.
Luiz José de Souza   +9 more
doaj   +1 more source

Comparison of clinical and laboratory characteristics between children and adults with dengue

open access: yesBrazilian Journal of Infectious Diseases
Over the past several years, the epidemiological profile of dengue has been changing progressively and is currently characterized by an increase in the number of cases in children under 15 years of age.
Luiz José de Souza   +6 more
doaj   +1 more source

Predictive value of persistent NS1 antigen positivity beyond 3rd day for dengue haemorrhagic fever in Sri Lankan children

open access: yesBMC Research Notes, 2019
Objective Dengue haemorrhagic fever (DHF) is a major public health concern responsible for significant morbidity in both adult and paediatric populations in Sri Lanka.
Mihira Manamperi   +4 more
doaj   +1 more source

A Transcriptomics-Based Bioinformatics Approach for Identification and In Vitro Screening of FDA-Approved Drugs for Repurposing against Dengue Virus-2

open access: yesViruses, 2022
The rising incidence of dengue virus (DENV) infections in the tropical and sub-tropical regions of the world emphasizes the need to identify effective therapeutic drugs against the disease.
Madhura Punekar   +6 more
doaj   +1 more source

Integrated vector control of Aedes aegypti mosquitoes around target houses

open access: yesParasites & Vectors, 2018
Background The developing fetuses of pregnant women are at high risk of developing serious birth defects following Zika virus infections. We applied an Integrated Vector Control (IVC) approach using source reduction, larviciding, and mass trapping with ...
Roberto Barrera   +3 more
doaj   +1 more source

Dengue and the heart

open access: yesCardiovascular Journal of Africa, 2021
Dengue is a neglected viral arthropod-borne tropical disease transmitted by the bite of infected Aedes spp. mosquitoes. It is responsible for a significant global burden of disease and corresponding socio-economic implications. There are four different virus serotypes, all of which are found predominantly in countries with tropical climates.
Araiza Garaygordobil, Diego   +10 more
openaire   +6 more sources

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