Results 51 to 60 of about 184,733 (289)

Integrated vector control of Aedes aegypti mosquitoes around target houses

Parasites & Vectors, 2018
Background The developing fetuses of pregnant women are at high risk of developing serious birth defects following Zika virus infections. We applied an Integrated Vector Control (IVC) approach using source reduction, larviciding, and mass trapping with ...
Roberto Barrera, Manuel Amador, Jorge Munoz, Veronica Acevedo   +3 more
doaj   +1 more source

Zika virus infection enhances future risk of severe dengue disease

Science, 2020
Double whammy Dengue and Zika virus epidemics have been lapping each other around the globe. These are closely related mosquito-borne viruses with about 40% homology within the envelope protein.
L. Katzelnick, César Narvaez, Sonia Arguello, Brenda Lopez Mercado, Damaris Collado, Oscarlett Ampie, Douglas Elizondo, Tatiana Miranda, Fausto Bustos Carillo, J. Mercado, Krista Latta, Amy J Schiller, Bruno Segovia-Chumbez, S. Ojeda, N. Sanchez, M. Plazaola, J. Coloma, M. Halloran, L. Premkumar, A. Gordon, Federico Narvaez, A. D. de Silva, G. Kuan, Á. Balmaseda, E. Harris   +24 more
semanticscholar   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Association of dengue virus‐specific polyfunctional T‐cell responses with clinical disease severity in acute dengue infection

Immunity, Inflammation and Disease, 2019
Introduction Although the role of dengue virus (DENV)‐specific T cells in the pathogenesis of acute dengue infection is emerging, the functionality of virus‐specific T cells associated with milder clinical disease has not been well studied.
Dulharie T. Wijeratne, Samitha Fernando, Laksiri Gomes, Chandima Jeewandara, Geethal Jayarathna, Yashoda Perera, Samurdhi Wickramanayake, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie N. Malavige   +9 more
doaj   +1 more source

RNA Isolation of Dengue Virus Type 2 with Different Precipitation Solvents : Methanol, Chloroform, and 2-Isopropanol.

Jurnal Kimia Riset, 2018
Dengue virus distributed in tropical and subtropical regions in the world. DENV viruses are transmitted between humans primarily by Aedes aegypti and Aedes albopictus mosquitoes and are endemic in most areas in which the vectors occur.
Yovilianda Maulitiva Untoro, Teguh Hari Sucipto, Harsasi Setyawati, Siti Churrotin, Ilham Harlan Amarullah, Puspa Wardhani, Aryati Aryati, Shuhai Ueda, Soegeng Soegijanto   +8 more
doaj   +1 more source

A Transcriptomics-Based Bioinformatics Approach for Identification and In Vitro Screening of FDA-Approved Drugs for Repurposing against Dengue Virus-2

Viruses, 2022
The rising incidence of dengue virus (DENV) infections in the tropical and sub-tropical regions of the world emphasizes the need to identify effective therapeutic drugs against the disease.
Madhura Punekar, Bhagyashri Kasabe, Poonam Patil, Mahadeo B. Kakade, Deepti Parashar, Kalichamy Alagarasu, Sarah Cherian   +6 more
doaj   +1 more source

Refining the Global Spatial Limits of Dengue Virus Transmission by Evidence-Based Consensus

PLoS Neglected Tropical Diseases, 2012
Background Dengue is a growing problem both in its geographical spread and in its intensity, and yet current global distribution remains highly uncertain.
O. Brady, P. Gething, S. Bhatt, J. Messina, J. Brownstein, A. Hoen, C. Moyes, A. Farlow, T. Scott, Simon Iain Hay   +9 more
semanticscholar   +1 more source

Prediction of dengue outbreak in Selangor Malaysia using machine learning techniques

Scientific Reports, 2021
Dengue fever is a mosquito-borne disease that affects nearly 3.9 billion people globally. Dengue remains endemic in Malaysia since its outbreak in the 1980’s, with its highest concentration of cases in the state of Selangor.
Nurul Azam Mohd Salim, Y. B. Wah, Caitlynn Reeves, Madison Smith, W. Yaacob, R. Mudin, Rahmat Dapari, N. N. F. F. Sapri, Ubydul Haque   +8 more
semanticscholar   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Dengue

Jornal de Pediatria, 1999
OBJECTIVE: To review the literature about epidemiological, clinical and preventive aspects of hemorrhagic dengue fever in children, and to provide Brazilian pediatricians with an update on dengue METHODS: We reviewed MEDLINE and classic texts.RESULTS: Dengue is an arbovirus disease, transmitted by Aedes aegypti, a mosquito that feeds indoors and is ...
openaire   +2 more sources