Results 71 to 80 of about 33,657 (222)

Adaptive Immunity to Dengue Virus: Slippery Slope or Solid Ground for Rational Vaccine Design?

Pathogens, 2020
The four serotypes of dengue virus are the most widespread causes of arboviral disease, currently placing half of the human population at risk of infection.
Lucas Wilken, Guus F. Rimmelzwaan
doaj   +1 more source

Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression

, 2005
Type 1 interferons (IFN-?/?) are key mediators of innate antiviral responses but havelittle effect on established replication of dengue viruses, which are mosquito-borneflaviviruses of immense global health importance.
Jones, M, Jacobs, M, Ball, S, Hibbert, L, Foster, G, Davidson, AD, Foster, GR, Davidson, A, Gruenwald, P, Schlaak, J   +9 more
core   +1 more source

Feasibility of case-control and test-negative designs to evaluate dengue vaccine effectiveness in Malaysia [PDF]

, 2019
Background: The world's first dengue vaccine [Dengvaxia; Sanofi Pasteur] was licensed in 2015 and others are in development. Real-world evaluations of dengue vaccines will therefore soon be needed.
Lim, Wei Yin, Junus, Suria, Linus Lojikip, Sharon, HSS, Amar Singh, Kumar, Suresh, Nealon, Joshua, Nachiappan, Jeyaseelan P., Moureau, Annick, Devi Sekaran, Shamala, Ochiai, R. Leon, Radigue, Cedric, Cowling, Benjamin J.   +11 more
core   +1 more source

Transcriptional responses of Aedes aegypti chemosensory tissues in response to volatile DEET and citronella oil

Insect Molecular Biology, EarlyView.
Aedes aegypti females were significantly repelled by both volatile DEET and citronella oil in comparison to control (ethanol‐exposed) mosquitoes. Global gene expression changes were largest in the mosquito mouthparts, with notable downregulation of the three subunits comprising the mosquito CO2 receptor (Gr1, 2 and 3).
Ivan Drahun, Jessica M. Sparrow, Cody W. Koloski, Bryan J. Cassone   +3 more
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Updated recommendations of the International dengue Initiative expert group for CYD-TDV vaccine implementation in Latin America

, 2019
Dengue disease represents a large and growing global threat to public health, causing a significant burden to health systems of endemic countries. For countries considering vaccination as part of their Integrated Management Strategy for Prevention and ...
Giambernardino, H. I.G., Castellanos-Martinez, J. M., Delrieu, Isabelle, Avila-Aguero, Maria L., Torres, Jaime, Torres, C. N, Falleiros-Arlant, Luiza Helena, Brea, J., Gessner, Bradford D., Mascareñas, Abiel   +9 more
core   +1 more source

Hospital at Home in 10 years—Here, borrow my binoculars

Journal of Internal Medicine, EarlyView.
Abstract Hospital in the Home (HAH) refers to the delivery of acute hospital care to patients at home, or in their usual place of care, including nursing homes. HAH is an acute hospital substitution service—it delivers medical, nursing and allied health staff, skills, interventions and treatments, technologies and supervision usually found in hospitals
Michael Montalto
wiley   +1 more source

Public acceptance and willingness-to-pay for a future dengue vaccine: a community-based survey in Bandung, Indonesia. [PDF]

PLoS Neglected Tropical Diseases, 2013
BackgroundAll four serotypes of dengue virus are endemic in Indonesia, where the population at risk for infection exceeds 200 million people. Despite continuous control efforts that were initiated more than four decades ago, Indonesia still suffers from ...
Panji Fortuna Hadisoemarto, Marcia C Castro   +1 more
doaj   +1 more source

Zoonotic anxieties: The cultural politics of Nepal's quest for pandemic preparedness

Medical Anthropology Quarterly, EarlyView.
Abstract Based on fieldwork conducted in Nepal (2022–2024) and by paying attention to how local and transnational notions of epidemiological risk are deployed, this ethnography introduces the concept of “zoonotic anxieties” to make sense of the multi‐species relational ethos that contemporary global health regimes propose.
Max D. López Toledano, Hari Basnet, Anna Durrance‐Bagale, Natasha Howard   +3 more
wiley   +1 more source

Risk of Dengue in Travelers: Implications for Dengue Vaccination [PDF]

Current Infectious Disease Reports, 2018
Dengue is found in tropics and subtropics that are considered to be popular travel destinations. We set out to review the burden of dengue on international travelers.GeoSentinel, a global network of travel medicine providers, has seen an increasing trend of dengue in returning travelers over the past decades.
openaire   +2 more sources