Results 71 to 80 of about 55,779 (204)

Consumer willingness to pay for dengue vaccine (CYD-TDV, Dengvaxia®) in Brazil : implication for future pricing considerations [PDF]

, 2017
Introduction and objective: Dengue virus is a serious global health problem with an estimated 3.97 billion people at risk for infection worldwide. In December 2015, the first vaccine (CYD-TDV) for dengue prevention was approved in Brazil, developed by ...
Alvares, Juliana, Brandão, Cristina Mariano Ruas, de Assis Acurcio, Francisco, Godman, Brian, Godói, Isabella Piassi, Guerra Júnior, Augusto Afonso, Lovato Pires de Lemos, Livia, Reis, Edna Afonso, Santos, André Soares   +8 more
core   +1 more source

Guillain–Barré Syndrome After Malaria: A Case Report of a 7‐Year‐Old Child With Asymmetric Onset of Acute Motor Axonal Neuropathy

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT This case highlights that acute motor axonal neuropathy can present with asymmetric, relapsing weakness in children. In malaria‐endemic and resource‐limited settings, clinicians should consider atypical Guillain–Barré variants early, as timely recognition and treatment can significantly improve outcomes despite diagnostic and systemic ...
Muath Ibrahim Mohammed Abusaada, Mustafa Mohamed Ibrahim Ali, Muotaman Mohammed Abdalla Adam, Mohammed Hishameldeen Omer Ali, Mohamed Abdallah Mohamed Baraka, Amjad Ali Mohamedelhassan Bakheit, Khabab Abbasher Hussien Mohamed Ahmed, Isameldin Yousif Khidir Mohmed   +7 more
wiley   +1 more source

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source

Nur77 Is Associated With Polyfunctional Properties in Virus‐Specific Human CD8+ T Cells

European Journal of Immunology, Volume 56, Issue 5, May 2026.
Nur77 is associated with a TCF‐1+ memory‐like, polyfunctional profile in virus‐specific human CD8+ T cells across acute‐resolved, vaccinated, and chronic viral infections, and its pharmacologic modulation in vitro enhances the functionality of dysfunctional HIV‐ and HBV‐specific CD8+ T cells in chronic co‐infections. ABSTRACT Human CD8+ T cells undergo
Fabiola Martel, Daniel Rincón, Caroline Passaes, Leonardo Arévalo, Marcela Torres, Natalia Ramirez, Carlos F. Narváez, Jessica F. Toro, Otto Sussmann, Manuel A. Franco, José Mateus, John Sidney, Alessandro Sette, Asier Sáez‐Cirión, Federico Perdomo‐Celis   +14 more
wiley   +1 more source

Dengue epidemic characteristics and vaccine research progress: a review

Zhongguo gonggong weisheng
Dengue fever is a mosquito-borne viral infectious disease transmitted by Aedes mosquitoes carrying the dengue virus (DENV). It is currently prevalent in over 100 tropical and subtropical countries and regions, and was listed by the WHO as one of the "Top
Jun LIU, Yanju QIN, Jiayun DING, Ruiting TANG, Qing XIE, Jian KUANG, Zhijian ZHOU   +6 more
doaj   +1 more source

Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan, Yuanyang Tan, Junhang Zhang, Xiaoya Liu, Jing Qu, Damien Chua, Hong Sheng Cheng, Joseph Han Sol Kim, Yu Xuan Liu, Changfei Qin, Yingzi Liu, Dezhi Li, Jikang Qiu, Mengshi Chi, Mingmin Bi, Qiwei Zhang, Yun Li, Masoumeh Motamedi Joibari, Stefan K Nilsson, Nguan Soon Tan, Yunping Fan, Liang Li   +21 more
wiley   +1 more source

Current Dengue Virus Vaccine Developments and Future Directions

Viruses
Dengue fever (DF), a leading arboviral disease globally, is caused by the Dengue virus (DENV) and represents a significant public health concern, with an estimated 390 million cases reported annually.
Govindaraj Anumanthan, Bikash Sahay, Ayalew Mergia   +2 more
doaj   +1 more source

Refined efficacy estimates of the Sanofi Pasteur dengue vaccine CYD-TDV using machine learning

Nature Communications, 2018
Clinical trials for the CYD-TDV dengue vaccine showed that vaccine efficacy varies with prior dengue exposure, but baseline serostatus is only known for 12% of subjects. Here, Dorigatti et al.
I. Dorigatti, C. A. Donnelly, D. J. Laydon, R. Small, N. Jackson, L. Coudeville, N. M. Ferguson   +6 more
doaj   +1 more source

Anti-dengue Vaccines: From Development to Clinical Trials

Frontiers in Immunology, 2020
Dengue Virus (DENV) is an arbovirus (arthropod-borne virus). Four serotypes of DENV are responsible for the infectious disease called dengue that annually affects nearly 400 million people worldwide.
Josilene Ramos Pinheiro-Michelsen, Josilene Ramos Pinheiro-Michelsen, Rayane da Silva Oliveira Souza, Itana Vivian Rocha Santana, Patrícia de Souza da Silva, Patrícia de Souza da Silva, Erick Carvalho Mendez, Wilson Barros Luiz, Jaime Henrique Amorim, Jaime Henrique Amorim   +9 more
doaj   +1 more source

Time-scale analysis non-local diffusion systems, applied to disease models

, 2020
The objective of the present paper is to use the well known Ross-Macdonald models as a prototype, incorporating spatial movements, identifying different times scales and proving a singular perturbation result using a system of local and non-local ...
Oliva, Sergio, Pereira, Marcone C., Sartori, Larissa M.   +2 more
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