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Immunopathogenesis of dengue virus infection

open access: yesJournal of Biomedical Science, 2001
Dengue virus infection causes dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS), whose pathogeneses are not clearly understood. Current hypotheses of antibody-dependent enhancement, virus virulence, and IFN-gamma/TNFalpha-mediated immunopathogenesis are insufficient to explain clinical manifestations of DHF/DSS such as ...
Huan-Yao Lei   +2 more
exaly   +3 more sources

Antiviral agents for dengue virus. [PDF]

open access: yesVirol Sin
Dengue virus (DENV) is a mosquito-borne pathogen responsible for a spectrum of illnesses, including dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. Nearly half of the global population is at risk of DENV infection, making it a pressing public health issue worldwide. The limited cross-protection among the four DENV serotypes (DENV1-4)
Jiang Y   +7 more
europepmc   +3 more sources

Interactions between mosquito genetic background and Wolbachia strain affect dengue virus blocking and fitness in South American populations of Aedes aegypti. [PDF]

open access: yesPLoS Neglected Tropical Diseases
The mosquito Aedes aegypti is the primary vector of dengue virus, and the release of mosquitoes infected with the bacterium Wolbachia is an increasingly used strategy to reduce dengue transmission.
Suk Lan Ser   +9 more
doaj   +2 more sources

Molecular Analysis of Dengue Virus Serotypes Circulating in Chennai, Tamil Nadu, India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Dengue fever is one of the most important arboviral infections all over the world. Globally, 50% of the human population is at risk of dengue virus infection.
Aridass Dhanasezhian   +4 more
doaj   +1 more source

Study of Dengue Virus Transovarial Transmission in Aedes spp. in Ternate City Using Streptavidin-Biotin-Peroxidase Complex Immunohistochemistry

open access: yesInfectious Disease Reports, 2022
Aedes aegypti is the most dominant vector in the transmission of dengue hemorrhagic fever (DHF). In addition to Ae. aegypti, Ae. albopictus is a secondary vector of the dengue virus, and both species are widespread in Indonesia.
Nia Kurnia   +5 more
doaj   +1 more source

Dengue Virus and Autophagy [PDF]

open access: yesViruses, 2011
Several independent groups have published that autophagy is required for optimal RNA replication of dengue virus (DENV). Initially, it was postulated that autophagosomes might play a structural role in replication complex formation. However, cryo-EM tomography of DENV replication complexes showed that DENV replicates on endoplasmic reticulum (ER ...
Nicholas S. Heaton, Glenn Randall
openaire   +3 more sources

Original antigenic sin in dengue - Hoskins effect

open access: yesAPIK Journal of Internal Medicine, 2023
Dengue is a mosquito-borne viral infection found in tropical and subtropical climates worldwide, mostly in urban and semiurban areas. The virus responsible for causing dengue is called dengue virus. There are four dengue virus serotypes, implying that it
Vasantha Kamath, Nisha Davy Olakkengi
doaj   +1 more source

Fighting the Dengue Virus [PDF]

open access: yesCureus, 2017
The incidence of dengue has been on the upsurge in the last decade. It has affected around one-third of the world's population living in endemic areas. It can be asymptomatic or may present with some specific symptoms. No control measures have proven beneficial to decrease the prevalence of this disease.
Faraz, Aniqa   +2 more
openaire   +2 more sources

Perbandingan Tingkat Keparahan Infeksi Sekunder Virus Dengue pada Keempat Serotipe di Indonesia: Systematic Review

open access: yesJurnal Kesehatan Andalas, 2021
Secondary infection with the dengue virus causes mild to severe manifestations. The distribution of dengue virus serotypes varies in various areas and can change over time.
Annelin Kurniati   +4 more
doaj   +1 more source

Dengue Virus

open access: yesClinics in Laboratory Medicine, 2010
Dengue is the most prevalent arthropod-borne virus affecting humans today. The virus group consists of 4 serotypes that manifest with similar symptoms. Dengue causes a spectrum of disease, ranging from a mild febrile illness to a life-threatening dengue hemorrhagic fever.
  +7 more sources

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