Lipidated dengue-2 envelope protein domain III independently stimulates long-lasting neutralizing antibodies and reduces the risk of antibody-dependent enhancement. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND: Dengue virus is a mosquito-transmitted virus that can cause self-limiting dengue fever, severe life-threatening dengue hemorrhagic fever and dengue shock syndrome.
Chen-Yi Chiang +9 more
doaj +1 more source
The Role Activity of Complement, TNFα & IL12 in Pathogenesis Dengue Virus
Indonesian Journal of Tropical and Infectious Disease, 2010 Dengue Virus infection is always found in some part of the world especially South East Asia including Indonesia. The pathogenesis of Dengue Virus infection is still controversial.
Soegeng Soegijanto +3 more
doaj +1 more source
Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections [PDF]
, 2015 Dengue virus (DENV) is a mosquito-borne flavivirus and a major international public health concern in many tropical and sub-tropical areas worldwide. DENV is divided into four major serotypes, and infection with one serotype leads to immunity against the
Barzon, Luisa +5 more
core +4 more sources
Development of Dengue virus type 2 replicons capable of prolonged expression in host cells
BMC Microbiology, 2001 Background As part of a program to develop a Dengue virus vaccine which avoids the deleterious effects of antibody dependent enhancement (ADE) of infection mediated by antibodies to Dengue virus structural proteins, we have begun to investigate the ...
Dayton Andrew I +2 more
doaj +1 more source
Immunopathogenesis of Dengue Virus Infection
Journal of Biomedical Science, 2001 Dengue virus infection causes dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS), whose pathogeneses are not clearly understood. Current hypotheses of antibody-dependent enhancement, virus virulence, and IFN-gamma/TNFalpha-mediated immunopathogenesis are insufficient to explain clinical manifestations of DHF/DSS such as ...
H Y, Lei +5 more
openaire +2 more sources
Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]
, 2014 Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle +3 more
core +1 more source
Journal of Infection and Public Health, 2019 Background: Dengue is a rapidly emerging arthropod borne viral infection affecting tropical and sub-tropical regions of the world. Dengue is an acute febrile illness but sometimes causes more fatal complications like dengue haemorrhagic fever (DHF) and ...
Nazish Parveen +9 more
doaj +1 more source
Rapid Detection and Molecular Typing of Dengue Virus by Using Multiplex-Nested-RT-PCR
Indonesian Journal of Biotechnology, 2006 world. We have evaluated the combination of one-step RT-PCR and multiplex nested PCR assays for detecting dengue viruses from clinical samples. Twelve patients were screened for the dengue virus, using a pair of primers that conserve for several ...
Nastiti Wijayanti +4 more
doaj +1 more source
Development of MVA-d34 Tetravalent Dengue Vaccine: Design and Immunogenicity
Vaccines, 2023 Dengue fever, an infectious disease that affects more than 100 million people every year, is a global health problem. Vaccination may be the most effective prevention strategy for the disease.
Ramil R. Mintaev +6 more
doaj +1 more source
The Effect of Rekattidiri Ovitrap Towards Aedes Aegypti Larval Density [PDF]
, 2017 Dengue Hemorrhagic Fever (DHF) is a health problem in Indonesia. The entire region of Indonesia at risk of contracting dengue disease. The study aims to prove the effect of modifications ovitrap rekattidiri on the density of larvae (HI: House Index, CI ...
Hadisaputro, S. (Soeharyo) +3 more
core +2 more sources