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Dengue Virus Pathogenesis: Innate Immune Signaling and Cell Death Receptor Pathways [PDF]
Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.ABSTRACT Background The infection caused by the dengue virus (DENV) involves a complicated interaction between viral replication and the body's immune responses. As the first line of defense, the innate immune response limits viral replication but can also lead to immunopathology if it is improperly regulated.
Farjana Islam
wiley +2 more sources
Dengue Vector Dynamics in Pakistan [PDF]
, 2012 During the last few year dengue has become an emerging vector borne disease in Pakistan. Aedes aegypti once considered eradicated from almost whole of Pakistan was again collected from 13 different cities.
Rasheed, Syed Basit
core +6 more sources
Antiviral agents for dengue virus [PDF]
Virologica SinicaDengue virus (DENV) is a mosquito-borne pathogen responsible for a spectrum of illnesses, including dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. Nearly half of the global population is at risk of DENV infection, making it a pressing public health issue worldwide. The limited cross-protection among the four DENV serotypes (DENV1-4)
Yinghan Jiang +7 more
openaire +3 more sources
Molecular Analysis of Dengue Virus Serotypes Circulating in Chennai, Tamil Nadu, India [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Dengue fever is one of the most important arboviral infections all over the world. Globally, 50% of the human population is at risk of dengue virus infection.
Aridass Dhanasezhian +4 more
doaj +1 more source
Infectious Disease Reports, 2022 Aedes aegypti is the most dominant vector in the transmission of dengue hemorrhagic fever (DHF). In addition to Ae. aegypti, Ae. albopictus is a secondary vector of the dengue virus, and both species are widespread in Indonesia.
Nia Kurnia +5 more
doaj +1 more source
Dengue Virus and Autophagy [PDF]
Viruses, 2011 Several independent groups have published that autophagy is required for optimal RNA replication of dengue virus (DENV). Initially, it was postulated that autophagosomes might play a structural role in replication complex formation. However, cryo-EM tomography of DENV replication complexes showed that DENV replicates on endoplasmic reticulum (ER ...
Heaton, Nicholas S., Randall, Glenn
openaire +3 more sources
Original antigenic sin in dengue - Hoskins effect
APIK Journal of Internal Medicine, 2023 Dengue is a mosquito-borne viral infection found in tropical and subtropical climates worldwide, mostly in urban and semiurban areas. The virus responsible for causing dengue is called dengue virus. There are four dengue virus serotypes, implying that it
Vasantha Kamath, Nisha Davy Olakkengi
doaj +1 more source
Fighting the Dengue Virus [PDF]
Cureus, 2017 The incidence of dengue has been on the upsurge in the last decade. It has affected around one-third of the world's population living in endemic areas. It can be asymptomatic or may present with some specific symptoms. No control measures have proven beneficial to decrease the prevalence of this disease.
Faraz, Aniqa +2 more
openaire +2 more sources
Jurnal Kesehatan Andalas, 2021 Secondary infection with the dengue virus causes mild to severe manifestations. The distribution of dengue virus serotypes varies in various areas and can change over time.
Annelin Kurniati +4 more
doaj +1 more source
Clinics in Laboratory Medicine, 2010 Dengue is the most prevalent arthropod-borne virus affecting humans today. The virus group consists of 4 serotypes that manifest with similar symptoms. Dengue causes a spectrum of disease, ranging from a mild febrile illness to a life-threatening dengue hemorrhagic fever.
+7 more sources