Results 71 to 80 of about 181,532 (295)

Quantitative Determination of Cellular-and Neurite Motility Speed in Dense Cell Cultures

open access: yesFrontiers in Neuroinformatics, 2019
Mobility quantification of single cells and cellular processes in dense cultures is a challenge, because single cell tracking is impossible. We developed a software for cell structure segmentation and implemented 2 algorithms to measure motility speed ...
Andreas W. Henkel   +3 more
doaj   +1 more source

ALEGRA-HEDP simulations of the dense plasma focus. [PDF]

open access: yes, 2009
We have carried out 2D simulations of three dense plasma focus (DPF) devices using the ALEGRA-HEDP code and validated the results against experiments. The three devices included two Mather-type machines described by Bernard et. al. and the Tallboy device currently in operation at NSTec in North Las Vegas.
Flicker, Dawn G.   +3 more
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plasma patches inside the polar cap and auroral oval: the impact on the spaceborne GPS receiver

open access: yesJournal of Space Weather and Space Climate, 2019
In this study, we focus on plasma patches with very dense plasma in the southern hemisphere during the main phase of 2015 St. Patrick’s Day storm. With in situ electron densities exceeding 1.5 × 1012 m−3 at 450–500 km altitude, the patches cause strong ...
Xiong Chao   +4 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Study of The Dynamical Behavior For Deuterons in Dense Plasma Focus

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
    The motion of fast deuterons in most dense plasma focus devices  ( DPF ) , may be characterized that it has a complex nature in its paths and this phenomena by describing a through gyrating motion with arbitrary changes in magnitude and direction . 
D. H. Yonas, R.H. Majeed
doaj  

The effect of a gas type on the soft X-ray yield from a plasma focus

open access: yesSt. Petersburg Polytechnical University Journal: Physics and Mathematics
Using the Lee code version (RADPFV5.15de), we carried out a series of numerical ‎experiments to find the parameters for the plasma focus and the soft X-ray yield for each of ‎nitrogen gas (molecular) and neon gas (atomic) within an appropriate ...
Nassif Alaa, Sahyouni Walid, Zeidan Ola
doaj   +1 more source

Ion sputter textured graphite [PDF]

open access: yes, 1982
A specially textured surface of pyrolytic graphite exhibits extremely low yields of secondary electrons and reduced numbers of reflected primary electrons after impingement of high energy primary electrons. An ion flux having an energy between 500 eV and
Curren, A. N.   +3 more
core   +1 more source

Laser-driven high-power X- and gamma-ray ultra-short pulse source

open access: yes, 2008
A novel ultra-bright high-intensity source of X-ray and gamma radiation is suggested. It is based on the double Doppler effect, where a relativistic flying mirror reflects a counter-propagating electromagnetic radiation causing its frequency ...
A. G. Zhidkov   +7 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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