Results 61 to 70 of about 6,470,188 (388)

Cosmic Shear of the Microwave Background: The Curl Diagnostic [PDF]

, 2005
Weak-lensing distortions of the cosmic-microwave-background (CMB) temperature and polarization patterns can reveal important clues to the intervening large-scale structure.
A. Stebbins, Asantha Cooray, D. J. Bacon, L. van Waerbeke, M. Bartelmann, Marc Kamionkowski, R. A. Sunyaev, R. D. Blandford, Robert R. Caldwell   +8 more
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Understanding the core density profile in TCV H-mode plasmas

, 2012
Results from a database analysis of H-mode electron density profiles on the Tokamak \`a Configuration Variable (TCV) in stationary conditions show that the logarithmic electron density gradient increases with collisionality.
A Pitzschke, Alberti S, Angioni C, Angioni C, Angioni C, Angioni C, Bortolon A, Bottino A, Casati A, Coda S, D Wágner, E Fable, Ernst D R Basse N Dorland W Fiore C L Lin L Long A Porkolab M Zeller K Zhurovich K, Fable E, Fable E, Fable E, H Weisen, Hofmann F, Lapillonne X, Martin Y, Maslov M, Maslov M Weisen H Zabolotsky A Porte L Angioni C Beurskens M the TCV team, Merz F, O Sauter, Porte L, Romanelli M, Ryter F, Stober J, Weisen H, Zabolotsky A   +29 more
core   +1 more source

Isolation of human salivary extracellular vesicles by iodixanol density gradient ultracentrifugation and their characterizations

Journal of Extracellular Vesicles, 2016
Diagnostic methods that focus on the extracellular vesicles (EVs) present in saliva have been attracting great attention because of their non-invasiveness.
Kazuya Iwai, T. Minamisawa, Kanako Suga, Y. Yajima, K. Shiba   +4 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Study on the effect of the size irregularity gradient of metal foams on macroscopic compressive properties

Heliyon, 2022
Size irregularity gradient and cell wall gradient, combined as the density gradient in previous studies, affect the macroscopic mechanical properties of the gradient metal foam. More and more complex mesostructures are designed and applied in metal foams,
Xiaoyang Zhang, Liqun Tang, Bao Yang, Heping Hu, Shifeng Tan   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Modeling vertical structure in circular velocity of spiral galaxy NGC 4244

, 2015
We study the vertical gradient in azimuthal velocity of spiral galaxy NGC 4244 in a thin disk model. With surface density accounting for the rotation curve, we model the gradient properties in the approximation of quasi-circular orbits and find the ...
Bratek, Łukasz, Jałocha, Joanna, Kutschera, Marek, Sikora, Szymon   +3 more
core   +1 more source

Engineering zonal cartilage through bioprinting collagen type II hydrogel constructs with biomimetic chondrocyte density gradient

BMC Musculoskeletal Disorders, 2016
BackgroundCartilage tissue engineering is a promising approach for repairing and regenerating cartilage tissue. To date, attempts have been made to construct zonal cartilage that mimics the cartilaginous matrix in different zones.
Xiang Ren, Fuyou Wang, Cheng Chen, X. Gong, Lijun Yin, Liu Yang   +5 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source