Results 61 to 70 of about 1,778,097 (289)

Optimization of in vitro fertilization with X-sorted spermatozoa in cattle

Frontiers in Animal Science
IntroductionDairy farming has a preferential demand for female calves to sustain milk production. Spermatozoa carrying the X chromosome, selected based on the higher content in DNA, allow to obtain almost exclusively female offspring.
Fernanda Fagali Franchi, Giulia Musmeci, Elena Alyfanti, Elena Alyfanti, Raquel Puelker, Valentina Lodde, Valentina Lodde, Federica Franciosi, Federica Franciosi   +8 more
doaj   +1 more source

Turbulence without pressure in d dimensions

, 1999
The randomly driven Navier-Stokes equation without pressure in d-dimensional space is considered as a model of strong turbulence in a compressible fluid. We derive a closed equation for the velocity-gradient probability density function.
A. Chekhlov, A. Polyakov, E. Balkovsky, E. Ivashkevich, J. Zinn-Justin, J.-P. Bouchaud, J.-P. Bouchaud, M. L. Mehta, S. A. Boldyrev, S. Boldyrev, S. Boldyrev, T. Gotoh, T. Gotoh, V. Gurarie, V. Yakhot, V. Yakhot, W. E   +16 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Understanding the core density profile in TCV H-mode plasmas

, 2012
Results from a database analysis of H-mode electron density profiles on the Tokamak \`a Configuration Variable (TCV) in stationary conditions show that the logarithmic electron density gradient increases with collisionality.
A Pitzschke, Alberti S, Angioni C, Angioni C, Angioni C, Angioni C, Bortolon A, Bottino A, Casati A, Coda S, D Wágner, E Fable, Ernst D R Basse N Dorland W Fiore C L Lin L Long A Porkolab M Zeller K Zhurovich K, Fable E, Fable E, Fable E, H Weisen, Hofmann F, Lapillonne X, Martin Y, Maslov M, Maslov M Weisen H Zabolotsky A Porte L Angioni C Beurskens M the TCV team, Merz F, O Sauter, Porte L, Romanelli M, Ryter F, Stober J, Weisen H, Zabolotsky A   +29 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Evaluación de las técnicas de capacitación espermática y su efecto en la fragmentación del ADN Assesment of sperm capacitation techniques and their effect on DNA fragmentation

Revista Colombiana de Obstetricia y Ginecología, 2012
Objetivo: evaluar el efecto de las técnicas de capacitación espermática en la fragmentación del ADN. Materiales y métodos: estudio experimental en el cual se describió el efecto de las técnicas de capacitación espermática swim up y gradientes de densidad
Luisa Calderón-Mendoza, Carlos Vivas-Ramírez, Lina De los Reyes   +2 more
doaj  

Mechanism investigation and models evaluation of gas transport in dual-porosity coal seam

Meitan kexue jishu
Methane is an unconventional natural gas in coal seams. Coalbed methane (CBM) migration behavior constitutes a core issue in coalbed methane extraction. However, there is no consensus on the gas migration mechanism of dual-porosity coal seams.
Wei LIU, Dongyang HAN, Hao XU, Yujun ZHOU, Tiannan LI   +4 more
doaj   +1 more source