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Differentiation Potential of Dental Papilla, Dental Pulp, and Apical Papilla Progenitor Cells

Journal of Endodontics, 2010
Regenerative endodontic procedures use the differentiation potential of embryonic and adult pulp progenitor cell populations to reconstitute dental structures.An in-depth search of the literature was accomplished to review biologic knowledge from basic research on tooth morphogenesis and differentiation, root development, dentin-pulp regeneration, pulp
Konstantinos Kodonas, Dimitrios Tziafas
exaly   +3 more sources

Cytoskeleton of the Mesenchymal Cells of the Rat Dental Papilla and Dental Pulp

Connective Tissue Research, 1995
This study describes the immunolocalization of actin, cytokeratins and vimentin during differentiation of the dental papilla in the rat. Incisors and first molars were sectioned from mandibles of Wistar rats from embryonic day (E)-14 to (E)-21 and weeks 1, 2, 3, 12 and 104 after birth, fixed in 90% alcohol, decalcified in EDTA, infiltrated with 5 ...
J R Ralphs, M Benjamin
exaly   +3 more sources

Wnt5a promotes differentiation of human dental papilla cells

International Endodontic Journal, 2010
Peng L, Ren LB, Dong G, Wang CL, Xu P, Ye L, Zhou XD. Wnt5a promotes differentiation of human dental papilla cells. International Endodontic Journal, 43, 404–412, 2010.AbstractAim  To investigate the role of Wnt5a in the process of differentiation of human dental papilla cells (HDPCs).Methodology  Recombinant adenovirus encoding full‐length Wnt5a cDNA
L Peng
exaly   +3 more sources

Effect of Wnt6 on Human Dental Papilla Cells In Vitro

Journal of Endodontics, 2010
The Wnt signaling pathway plays an important role in tissue development by acting on proliferation, differentiation, and cell fate decisions. Because the role of Wnt6 in tooth development was still unknown, the purpose of this study was to investigate the role of Wnt6 in tooth morphogenesis and dental tissue mineralization by elucidating its effect on ...
Chenglin Wang, Gang Dong
exaly   +3 more sources

Osteogenic differentiation of human dental papilla mesenchymal cells

Biochemical and Biophysical Research Communications, 2006
We isolated dental papilla from impacted human molar and proliferated adherent fibroblastic cells after collagenase treatment of the papilla. The cells were negative for hematopoietic markers but positive for CD29, CD44, CD90, CD105, and CD166.
Motohiro Hirose   +2 more
exaly   +3 more sources

Hormesis and dental apical papilla stem cells

Chemico-Biological Interactions, 2022
This paper provides an assessment of hormetic dose responses by stem cells of the apical papilla (SCAPs) from humans. Hormetic dose responses were induced in vitro by a broad range of agents, including dietary supplements (e.g., berberine, EGCG, resveratrol), pharmaceutical/commercial substances (e.g.
openaire   +2 more sources

Expression of hepatocyte growth factor/scatter factor and c-Met in human dental papilla and fibroblasts from dental papilla

Archives of Oral Biology, 1999
Hepatocyte growth factor/scatter factor (HGF/SF), a broad-spectrum and multifunctional cytokine, is essential for the development of tissues including tooth. Here it was found that the HGF/SF content of human dental papillae obtained from 8 to 16-year-old individuals decreased significantly with age.
Y Daikuhara, Naokatu Arakaki
exaly   +3 more sources

Dental Apical Papilla as Therapy for Spinal Cord Injury

Journal of Dental Research, 2015
Stem cells of the apical papilla (SCAP) represent great promise regarding treatment of neural tissue damage, such as spinal cord injury (SCI). They derive from the neural crest, express numerous neurogenic markers, and mediate neurite outgrowth and axonal targeting.
De Berdt, P   +7 more
openaire   +2 more sources

Calcification of the dental papilla. A rare finding

British Dental Journal, 1989
An interesting case is reported, of calcification of the dental papilla. As yet, little is known about this asymptomatic calcification, which constitutes a rare radiographic finding, deforming the root of a vital tooth, generally a lower premolar or canine.
openaire   +2 more sources

AKT from dental epithelium to papilla promotes odontoblast differentiation

Differentiation, 2023
Epithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear.
Jiangyi, Wang   +10 more
openaire   +2 more sources

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