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Production of monoclonal antibodies against murine dental papilla
European Journal of Oral Sciences, 1988Abstract – The mesenchymal component of the embryonic tooth, the dental papilla, shows unique cellular behavior. Only the dental papilla cells are capable of differentiating into odontoblasts. The dental papilla also directs the morphogenesis of the tooth.
S, Vainio +3 more
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Cell pellets from dental papillae can reexhibit dental morphogenesis and dentinogenesis
Biochemical and Biophysical Research Communications, 2006We isolated dental papilla mesenchymal cells (DPMCs) from different rat incisor germs at the late bell stage and incubated them as cell pellets in polypropylene tubes. In vitro pellet culture of DPMCs presented several crucial characteristics of odontoblasts, as indicated by accelerated mineralization, positive immunostaining for dentin ...
Jin-Hua, Yu +6 more
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Expression of intermediate filaments and actins in human dental pulp and embryonic dental papilla
The Anatomical Record, 1992AbstractThe localization of different cytoskeletal proteins (keratin, vimentin, desmin, actin, and α‐smooth muscle actin) was examined by immunohistochemistry in normal human adult dental pulp and compared with dental papilla of tooth germs. Keratin and actin were localized in enamel organ.
Lombardi T +5 more
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The influence of the donor on dental apical papilla stem cell properties
Tissue and Cell, 2015Stem cells from the human dental apical papilla (SCAP) can be obtained from almost all extracted wisdom teeth with an immature tooth root. Although different stem cell lines are used for studies, it remains elusive whether specific characteristics of the dental stem cell cultures such as proliferation rates or the cell differentiation potential are ...
C Morsczeck
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International Endodontic Journal, 2012
AbstractAimTo establish a cell line of immortalized human dental papilla cells (hDPCs).MethodologyPrimary hDPCs were cultured and infected with lentivirus containing the hTERT gene. Integration and transcription of the hTERT gene were verified by PCR. The characteristics of the cells, such as morphology, proliferation and mineralization, were analysed.
G B, Yang +4 more
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AbstractAimTo establish a cell line of immortalized human dental papilla cells (hDPCs).MethodologyPrimary hDPCs were cultured and infected with lentivirus containing the hTERT gene. Integration and transcription of the hTERT gene were verified by PCR. The characteristics of the cells, such as morphology, proliferation and mineralization, were analysed.
G B, Yang +4 more
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Dental Papilla Cells Synthesize But Do Not Deposit Fibronectin in Culture
Journal of Dental Research, 1987The dental papilla cells play a major regulatory role during tooth morphogenesis, and they are the only mesenchymal cells capable of differentiating into odontoblasts secreting dentin. In this paper, we have extended our studies on the behavior of cultured dental papilla cells which have been disaggregated from 17-day mouse embryo teeth.
I, Thesleff +3 more
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An investigation of S-100 protein in embryonic dental papillae of rats
Oral Surgery, Oral Medicine, Oral Pathology, 1984We attempted to identify S-100 protein, a marker of neural crest tissue, within cells of the developing dental papillae of 18-day rat fetuses by means of the immunoperoxidase technique. Although there is experimental evidence that dental papillae are derived from neural crest, no marker protein was identified in this study.
C, Dunlap +3 more
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Mineralized nodule formation by human dental papilla cells in culture
European Journal of Oral Sciences, 1997Human dental papilla cells were enzymatically separated from deciduous tooth germs of an 8‐month‐old embryo legally aborted. the second passage cells were cultured up to 35 days in 3 groups. The β‐gp group was cultured in the Dulbecco MEM containing ascorbic acie and β‐glycerophosphate supplemented with 15% fetal bovine serum.
J, Hao +5 more
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WNT5A inhibits human dental papilla cell proliferation and migration
Biochemical and Biophysical Research Communications, 2009WNT proteins are a large family of cysteine-rich secreted molecules that are linked to both canonical and non-canonical signal pathways, and have been implicated in oncogenesis and tissue development. Canonical WNT proteins have been proven to play critical roles in tooth development, while little is known about the role of non-canonical WNT proteins ...
L, Peng +6 more
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Formation of bone-like tissue by dental follicle cells co-cultured with dental papilla cells
Cell and Tissue Research, 2010During tooth root formation, dental follicle cells (DFCs) differentiate into osteoblasts/cementoblasts when they are in contact with pre-existing dentin. Since some factors of dentin matrix were also produced by dental papilla cells (DPCs) and could induce DFCs differentiation, we hypothesized that DPCs can directly promote DFCs differentiation and ...
Yudi, Bai +6 more
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