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Immortalization and characterization of mouse dental papilla cells
Mouse dental papilla cells (MDPCs) can be differentiated into component cell types that have the ability to regenerate the pulpo-dentinal complex. At the cap stage of tooth development MDPC component cells are programmed for tooth generation. Therefore, isolated and cultivated component cells can be useful in evaluating cellular, molecular, and ...
Green, DW +3 more
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Objective: The aim of the present study was (a) to evaluate the relationship between dental implant mucosa and dental implant papilla levels; and (b) to identify the clinical parameters associated with peri-implant soft tissue stability over time ...
Julia Garabetyan +2 more
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Hormesis and dental apical papilla stem cells
Chemico-Biological Interactions, 2022This paper provides an assessment of hormetic dose responses by stem cells of the apical papilla (SCAPs) from humans. Hormetic dose responses were induced in vitro by a broad range of agents, including dietary supplements (e.g., berberine, EGCG, resveratrol), pharmaceutical/commercial substances (e.g.
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AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation, 2023Epithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear.
Jiangyi, Wang +10 more
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Calcification of the dental papilla. A rare finding
British Dental Journal, 1989An interesting case is reported, of calcification of the dental papilla. As yet, little is known about this asymptomatic calcification, which constitutes a rare radiographic finding, deforming the root of a vital tooth, generally a lower premolar or canine.
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Production of monoclonal antibodies against murine dental papilla
European Journal of Oral Sciences, 1988Abstract – The mesenchymal component of the embryonic tooth, the dental papilla, shows unique cellular behavior. Only the dental papilla cells are capable of differentiating into odontoblasts. The dental papilla also directs the morphogenesis of the tooth.
S, Vainio +3 more
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Cell pellets from dental papillae can reexhibit dental morphogenesis and dentinogenesis
Biochemical and Biophysical Research Communications, 2006We isolated dental papilla mesenchymal cells (DPMCs) from different rat incisor germs at the late bell stage and incubated them as cell pellets in polypropylene tubes. In vitro pellet culture of DPMCs presented several crucial characteristics of odontoblasts, as indicated by accelerated mineralization, positive immunostaining for dentin ...
Jin-Hua, Yu +6 more
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Expression of intermediate filaments and actins in human dental pulp and embryonic dental papilla
The Anatomical Record, 1992AbstractThe localization of different cytoskeletal proteins (keratin, vimentin, desmin, actin, and α‐smooth muscle actin) was examined by immunohistochemistry in normal human adult dental pulp and compared with dental papilla of tooth germs. Keratin and actin were localized in enamel organ.
Lombardi T +5 more
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International Endodontic Journal, 2012
AbstractAimTo establish a cell line of immortalized human dental papilla cells (hDPCs).MethodologyPrimary hDPCs were cultured and infected with lentivirus containing the hTERT gene. Integration and transcription of the hTERT gene were verified by PCR. The characteristics of the cells, such as morphology, proliferation and mineralization, were analysed.
G B, Yang +4 more
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AbstractAimTo establish a cell line of immortalized human dental papilla cells (hDPCs).MethodologyPrimary hDPCs were cultured and infected with lentivirus containing the hTERT gene. Integration and transcription of the hTERT gene were verified by PCR. The characteristics of the cells, such as morphology, proliferation and mineralization, were analysed.
G B, Yang +4 more
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Mineralized nodule formation by human dental papilla cells in culture
European Journal of Oral Sciences, 1997Human dental papilla cells were enzymatically separated from deciduous tooth germs of an 8‐month‐old embryo legally aborted. the second passage cells were cultured up to 35 days in 3 groups. The β‐gp group was cultured in the Dulbecco MEM containing ascorbic acie and β‐glycerophosphate supplemented with 15% fetal bovine serum.
J, Hao +5 more
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