Immunomodulation stimulates the innervation of engineered tooth organ [PDF]
, 2014 The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault +5 more
core +5 more sources
Monitoring Notch Signaling-Associated Activation of Stem Cell Niches within Injured Dental Pulp
Frontiers in Physiology, 2017 Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and ...
Thimios A. Mitsiadis +4 more
doaj +1 more source
Dental Pulp Stem Cell Mechanoresponsiveness: Effects of Mechanical Stimuli on Dental Pulp Stem Cell Behavior [PDF]
Frontiers in Physiology, 2018 Dental pulp is known to be an accessible and important source of multipotent mesenchymal progenitor cells termed dental pulp stem cells (DPSCs). DPSCs can differentiate into odontoblast-like cells and maintain pulp homeostasis by the formation of new dentin which protects the underlying pulp.
Marrelli M. +6 more
openaire +4 more sources
The effects of ageing on dental pulp stem cells, the tooth longevity elixir [PDF]
European Cells & Materials, 2019 Stem cells are essential for tissue homeostasis and regeneration throughout the lifespan of multicellular rganisms. The decline in stem cell function during advanced age is associated with a reduced regenerative potential of tissues that leads to an ...
I Iezzi +3 more
doaj +1 more source
Extruded Nucleoli of Human Dental Pulp Cells. [PDF]
Medicina (Kaunas), 2022 Background and Objectives: The dental pulp stem cells are highly proliferative and can differentiate into various cell types, including endothelial cells. We aimed to evaluate the ultrastructural characteristics of the human dental pulp cells of the permanent frontal teeth.
Rusu MC +8 more
europepmc +5 more sources
Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]
, 2017 Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna +6 more
core +2 more sources
Distal C terminus of CaV1.2 channels plays a crucial role in the neural differentiation of dental pulp stem cells. [PDF]
PLoS ONE, 2013 L-type voltage-dependent CaV1.2 channels play an important role in the maintenance of intracellular calcium homeostasis, and influence multiple cellular processes.
Jianping Ge +6 more
doaj +1 more source
Current applications and future prospects of stem cells in dentistry [PDF]
, 2015 Stem cells are defined as clonogenic, unspecialized cells capable of both self-renewal and multi-lineage differentiation, contributing to regenerating specific tissues. For years, restorative treatments have exploited the lifelong regenerative potential
Sivamurthy, Gautham, Surendran, Sharmila
core +2 more sources
Epigenetic regulation of dental-derived stem cells and their application in pulp and periodontal regeneration [PDF]
PeerJ, 2023 Dental-derived stem cells have excellent proliferation ability and multi-directional differentiation potential, making them an important research target in tissue engineering.
Yuyang Chen +4 more
doaj +2 more sources
Role of Prion protein-EGFR multimolecular complex during neuronal differentiation of human dental pulp-derived stem cells [PDF]
, 2018 Cellular prion protein (PrPC) is expressed in a wide variety of stem cells in which regulates their self-renewal as well as differentiation potential. In this study we investigated the presence of PrPCin human dental pulp-derived stem cells (hDPSCs) and ...
Manganelli, Valeria +6 more
core +1 more source