Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]
, 2011 Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey +39 more
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Ability of stem and progenitor cells in the dental pulp to form hard tissue
Japanese Dental Science Review, 2015 Dental pulp has an important ability to form mineralized hard tissue in response to a variety of external stimuli. The formation of mineralized tissue within the pulp cavity has been widely examined in both clinical and animal studies.
Akihiro Hosoya, DDS, PhD +1 more
doaj +1 more source
Monitoring Notch Signaling-Associated Activation of Stem Cell Niches within Injured Dental Pulp
Frontiers in Physiology, 2017 Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and ...
Thimios A. Mitsiadis +4 more
doaj +1 more source
Dental Pulp Cell Behavior in Biomimetic Environments [PDF]
Journal of Dental Research, 2015 There is emerging recognition of the importance of a physiologically relevant in vitro cell culture environment to promote maintenance of stem cells for tissue engineering and regenerative medicine purposes. In vivo, appropriate cellular cues are provided by local tissue extracellular matrix (ECM), and these are not currently recapitulated well in ...
Smith, J. G. +3 more
openaire +4 more sources
The effects of ageing on dental pulp stem cells, the tooth longevity elixir [PDF]
European Cells & Materials, 2019 Stem cells are essential for tissue homeostasis and regeneration throughout the lifespan of multicellular rganisms. The decline in stem cell function during advanced age is associated with a reduced regenerative potential of tissues that leads to an ...
I Iezzi +3 more
doaj +1 more source
Role of Prion protein-EGFR multimolecular complex during neuronal differentiation of human dental pulp-derived stem cells [PDF]
, 2018 Cellular prion protein (PrPC) is expressed in a wide variety of stem cells in which regulates their self-renewal as well as differentiation potential. In this study we investigated the presence of PrPCin human dental pulp-derived stem cells (hDPSCs) and ...
Manganelli, Valeria +6 more
core +1 more source
The biological properties of OGI surfaces positively act on osteogenic and angiogenic commitment of mesenchymal stem cells [PDF]
, 2017 Osteogenesis process displays a fundamental role during dental implant osteointegration. In the present work, we studied the influence of Osteon Growth Induction (OGI) surface properties on the angiogenic and osteogenic behaviors of ...
Bressan, Eriberto +7 more
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Oral plaque from Type 2 diabetic patients reduces the clonogenic capacity of dental pulp-derived mesenchymal stem cells [PDF]
, 2019 Type 2 diabetes (T2D) is a major metabolic disease and a key epigenetic risk factor for the development of additional clinical complications. Among them, periodontitis (PD), a severe inflammatory disease ascribable to a dysregulated physiology and ...
Bordin, Antonella +9 more
core +1 more source
Distal C terminus of CaV1.2 channels plays a crucial role in the neural differentiation of dental pulp stem cells. [PDF]
PLoS ONE, 2013 L-type voltage-dependent CaV1.2 channels play an important role in the maintenance of intracellular calcium homeostasis, and influence multiple cellular processes.
Jianping Ge +6 more
doaj +1 more source
Graphene-based nanomaterials for tissue engineering in the dental field [PDF]
, 2018 The world of dentistry is approaching graphene-based nanomaterials as substitutes for tissue engineering. Apart from its exceptional mechanical strength, electrical conductivity and thermal stability, graphene and its derivatives can be functionalized ...
Antoniac, I +9 more
core +1 more source