Results 91 to 100 of about 1,148,937 (245)

Construction of Recombinant Plasmid pcDNA3.1/BMP-2 and its Involvement in Differentiation of Human Dental Pulp-Derived Cells into an Odontoblastic Lineage

Makara Journal of Health Research, 2010
Experimental studies have shown that dental pulp tissue has potential to regenerate dentine in response to adverse stimuli, such as caries and associated operative procedures.
Hedijanti Joenoes, Mindia Yuniastuti, Endang W. Bachtiar, Boy M. Bachtiar   +3 more
doaj   +1 more source

Biocompatibility With Osteogenic Potential of Premixed Bioceramic Cements for Use in Apical Surgery

Australian Endodontic Journal, EarlyView.
ABSTRACT This study investigated the biocompatibility and osteogenic potential of premixed bioceramic cements (PBCs)—CeraPutty, EndoCEM MTA Premixed, Well‐Root PT, and One‐Fil PT Injectable—as alternatives to mineral trioxide aggregate for retrograde filling in endodontic microsurgery.
Yesol Kim, Jae‐Hoon Kim, Unni Krishnan, Hyeon‐Cheol Kim, Minju Song, Sang Won Kwak   +5 more
wiley   +1 more source

Dental Pulp Stem Cell‐Derived Intracellular Vesicles Inhibit OSCC by Delivering PTEN to Suppress PI3K/AKT/mTOR Signalling Pathway

Cell Proliferation, EarlyView.
DPSC‐IVs suppressed PI3K/AKT/mTOR signalling pathway by delivering PTEN to tumour cells, which reduced the expression of Bcl‐2 and elevated that of Bax. Meanwhile, DPSC‐IVs activated PINK1/Parkin mediated mitophagy, which further raised ROS levels.
Yu Luo, Qiang Qin, Wenting She, Xiangying Wang, Xiqin Li, Chenxuan Shu, Ruohan Li, Ziwei Li, Dongjie Fu, Yan He, Qingsong Ye   +10 more
wiley   +1 more source

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source

A carbon dot nanozyme hydrogel enhances pulp regeneration activity by regulating oxidative stress in dental pulpitis

Journal of Nanobiotechnology
Preserving pulp viability and promoting pulp regeneration in pulpitis have attracted widespread attention. Restricted by the oxidative stress microenvironment of dental pulpitis, excessive reactive oxygen and nitrogen species (RONS) trigger uncontrolled ...
Yingjuan Zhang, Xianxian Huang, Yicai Luo, Xiangyu Ma, Ling Luo, Ling Liang, Tingting Deng, Yang Qiao, Fanggui Ye, Hongbing Liao   +9 more
doaj   +1 more source

A Novel CD24+ Subpopulation For Pulpitis Traeatment And Pulp Regeneration

International Dental Journal
Aim or purpose: The pulp regeneration strategy is important to treat pulpitis and pulp necrosis. Yet the key functional subpopulation and mechanism that governs the odontogenic fate decisions remain largely unknown. Materials and methods: In our study, a
Cheng Liang
doaj   +1 more source

Dental pulp stem cells, niches, and notch signaling in tooth injury

, 2011
Stem cells guarantee tissue repair and regeneration throughout life. The decision between cell self-renewal and differentiation is influenced by a specialized microenvironment called the 'stem cell niche'.
Feki, A, Catón, J, A. Feki, Papaccio, G, T.A. Mitsiadis, J. Catón, G. Papaccio, Mitsiadis, T A, Catón J, Mitsiadis TA, Feki A, Papaccio G   +11 more
core   +1 more source

Revitalization in Traumatized Immature Teeth With External Inflammatory Root Resorption: A Systematic Review

Dental Traumatology, EarlyView.
ABSTRACT Introduction This study aimed to evaluate whether revitalization can be indicated in the treatment of traumatized immature teeth with external inflammatory root resorption (EIRR). Methods The protocol of the review was developed in accordance with the PRISMA checklist and registered in the PROSPERO database (CRD42023446609).
Ghina Al Khourdaji, Timothy Fasham, Samantha Elbhar, Kerstin M. Galler, Tchilalo Boukpessi   +4 more
wiley   +1 more source

Prognosis of Traumatized Permanent Teeth Affected by Multiple Injuries (Combination Injuries): A Systematic Review and Meta‐Analysis

Dental Traumatology, EarlyView.
ABSTRACT Background/Aims The prognosis of traumatic dental injuries (TDI) of permanent teeth depends on several factors related to the injury, patient characteristics, management, and follow‐up protocols. When such injuries affect both hard dental tissues and the periodontium (“combination injuries”), the risk of adverse healing complications increases.
Nitesh Tewari, Alina Wikstrom, Eva Lauridsen, Vijay Prakash Mathur, Partha Haldar, Lars Andersson, Georgios Tsilingaridis   +6 more
wiley   +1 more source