Results 71 to 80 of about 1,085,447 (191)

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Gene-enhanced tissue engineering for dental hard tissue regeneration: (2) dentin-pulp and periodontal regeneration

Head & Face Medicine, 2006
Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone grafting of large osseous defects in ...
Mason James M, Edwards Paul C
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Angiogenic regulation of dental pulp stem cells

Frontiers in Dental Medicine
Tissue regeneration relies on the ingrowth of blood vessels from the host for the survival and functionalization of regenerated tissues. Any holdup in this process can threaten the viability of the transplanted progenitor cells, which in turn can hinder ...
Waruna Lakmal Dissanayaka, Nunthawan Nowwarote, Nunthawan Nowwarote, Tanida Srisuwan, Sirawut Hiran-Us, Chatvadee Kornsuthisopon, Xiaofei Zhu, Thanaphum Osathanon   +7 more
doaj   +1 more source

Dental pulp derived mesenchymal stromal cells

This book presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration.? In this thoroughly updated and expanded second edition, the author covers mesenchymal stem cell
Yildirim, Sibel
core   +1 more source

Expression of high mobility group box 1 in inflamed dental pulp and its chemotactic effect on dental pulp cells

, 2014
High mobility group box 1 protein (HMGB1) is a chromatin protein which can be released extracellularly, eliciting a pro-inflammatory response and promoting tissue repair process.
Jiang, Hongwei, Zhang, Xufang, Huang, Yihua, Fan, Chen, Ling, Junqi, Gong, Qimei   +5 more
core   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source

Current and future options for dental pulp therapy

Japanese Dental Science Review, 2019
Summary: Dental pulp is a connective tissue and has functions that include initiative, formative, protective, nutritive, and reparative activities. However, it has relatively low compliance, because it is enclosed in hard tissue.
Takahiko Morotomi, Ayako Washio, Chiaki Kitamura   +2 more
doaj   +1 more source

Dental follicle stem cells rescue the regenerative capacity of inflamed rat dental pulp through a paracrine pathway

Stem Cell Research & Therapy, 2020
Background Pulpitis is a common dental disease characterized by sustained inflammation and impaired pulp self-repair. Mesenchymal stem cell-based minimally invasive vital pulp therapy (MSC-miVPT) is a potential treatment method, but its application is ...
Hong Hong, Xiaochuan Chen, Kun Li, Nan Wang, Mengjie Li, Bo Yang, Xiaoqi Yu, Xi Wei   +7 more
doaj   +1 more source

Utilização de Células-Tronco de Polpa de Dentes Permanentes Humanos (DPSCs) na Regeneração de Defeitos Ósseos Mandibulares [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Desde que se descobriu o potencial das células-tronco (CT) adultas em formar diferentes tecidos, estas têm sido exploradas em busca de alternativas ...
Stuepp, Rúbia Teodoro
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