Results 101 to 110 of about 17,547 (221)

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Effect of three different root canal sealants on human dental pulp stem cells

Scientific Reports
The cytotoxic effects of three root canal sealers with different bases on human dental pulp stem cells were assessed in this study using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) test.
Ahmad Alfahlawy, Manar A. A. Selim, Hayam Y. Hassan   +2 more
doaj   +1 more source

Dose‐dependent effects of photobiomodulation on stem cells from human exfoliated deciduous teeth cultured on polylactic acid films: An in vitro study

Photochemistry and Photobiology, EarlyView.
660‐nm photobiomodulation increased metabolic activity, modulated cell cycle distribution, and increased apparent surface coverage in dental stem cells cultured on polylactic acid films, with 4 J/cm2 producing the most consistent response and a greater G2/M fraction than 1 J/cm2.
Rômulo Augusto de Paiva Macedo, Vladimir Galdino Sabino, Hugo Alexandre Oliveira Rocha, Moacir Franco de Oliveira, Carlos Eduardo Bezerra de Moura, Carlos Augusto Galvão Barboza   +5 more
wiley   +1 more source

Potential impact of low-level laser therapy on Wnt/β-catenin signaling pathway for regenerative endodontic applications: A literature review

Photodiagnosis and Photodynamic Therapy
Regenerative endodontics seeks to restore the structure and function of the pulp–dentin complex by harnessing endogenous or transplanted stem cells, bioactive signals, and scaffold-based microenvironments.
Rashin Bahrami, Atefe Ebrahimi, Mina Mehrjouei   +2 more
doaj   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Human dental pulp stem cells differentiation: A review

Journal of Craniomaxillofacial Research, 2018
The advent of regenerative medicine has brought us the opportunity to regenerate, modify and restore human organs function. Stem cells, a key resource in regenerative medicine, are defined as clonogenic, self-renewing, progenitor cells that can generate ...
Elham Mohammadi Golrang, Fatemeh Dibaji, Naghmeh Bahrami, Atena Mohammadi Golrang   +3 more
doaj  

Chemical agents to control biofilm formation in step 1 of care—Toothpastes and mouthwashes/concepts and challenges

Periodontology 2000, EarlyView.
Abstract Maintaining optimal oral hygiene is important for overall oral care, ensuring the well‐being of teeth and their surrounding tissues. In addition, it promotes fresh breath and a pleasing smile. A key element of oral self‐care is the daily use of toothpaste during regular brushing.
Maud Joosstens, Cees Valkenburg, Fridus Van der Weijden   +2 more
wiley   +1 more source

Dental pulp as a stem cell reservoir.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2014
Currently, much information is provided regarding the presence and the roles in tissue regeneration of stem cell niches residing in post-natal dental pulp. So far, three types of adult stem cells have been isolated from dental pulp. Correct evaluation of these cells is important in order to determine their potential use in clinical fields.
Andreea Cristiana, Didilescu, M C, Rusu, G, Nini   +2 more
openaire   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source