Results 91 to 100 of about 109,219 (372)
Vital Pulp Therapy—Current Progress of Dental Pulp Regeneration and Revascularization [PDF]
, 2010 Pulp vitality is extremely important for the tooth viability, since it provides nutrition and acts as biosensor to detect pathogenic stimuli. In the dental clinic, most dental pulp infections are irreversible due to its anatomical position and ...
Yelick, Pamela C., Zhang, Weibo
core +3 more sources
PLoS ONE, 2020 Clinical studies have recently demonstrated that autologous transplantation of mobilized dental pulp stem cells is a safe and efficacious potential therapy for pulp regeneration.
Ai Orimoto +5 more
doaj +1 more source
Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells
Cells, 2020 Dental pulp stem cells (DPSCs) from adult teeth show the expression of a very complete repertoire of stem pluripotency core factors and a high plasticity for cell reprogramming.
Véronica Uribe-Etxebarria +7 more
semanticscholar +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
Advanced Healthcare Materials, EarlyView.What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell +5 more
wiley +1 more source
Advanced Science, EarlyView.The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu +13 more
wiley +1 more source
Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration
Advanced Science, EarlyView.This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong +17 more
wiley +1 more source
Dental pulp stem cells for salivary gland regeneration : where are we today? [PDF]
, 2023 Xerostomia is the phenomenon of dry mouth and is mostly caused by hypofunction of the salivary glands. This hypofunction can be caused by tumors, head and neck irradiation, hormonal changes, inflammation or autoimmune disease such as Sjögren’s syndrome ...
Eckert, Alexander W. +5 more
core +1 more source
Effect of Dedifferentiation on Time to Mutation Acquisition in Stem Cell-Driven Cancers [PDF]
, 2013 Accumulating evidence suggests that many tumors have a hierarchical organization, with the bulk of the tumor composed of relatively differentiated short-lived progenitor cells that are maintained by a small population of undifferentiated long-lived cancer stem cells.
arxiv +1 more source
Using single-cell entropy to describe the dynamics of reprogramming and differentiation of induced pluripotent stem cells [PDF]
, 2020 Induced pluripotent stem cells (iPSCs) provide a great model to study the process of reprogramming and differentiation of stem cells. Single-cell RNA sequencing (scRNA-seq) enables us to investigate the reprogramming process at single-cell level. Here, we introduce single-cell entropy (scEntropy) as a macroscopic variable to quantify the cellular ...
arxiv +1 more source
Advanced Science, EarlyView.Polyaspartic acid‐calcium‐lanthanum (PAsp‐Ca‐La) complexes could induce antibacterial remineralization of demineralized dentin and in‐depth occlusion of dentinal tubules (DTs) with lanthanum‐doped hydroxyapatite (La‐HAp) via polyelectrolyte‐cation complexes pre‐precursor (PCCP) process, allowing the release of La3+ in response to acids generated by ...
Ling Zhu +12 more
wiley +1 more source