Results 111 to 120 of about 5,623,817 (263)
The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL-8-Dependent VEGF Regulation: An In Vitro Study. [PDF]
Int Endod JABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Thalakiriyawa DS +5 more
europepmc +2 more sources
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
Medicinal Research Reviews, EarlyView.ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Human Dental Pulp Stem Cells: The Culture Optimization for Increased Growth [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2009 Introduction: Dental pulp-derived mesenchymal stem cells (MSCs) have emerged as a promising tool for use in regenerative medicine. The in vitro growth kinetic and culture requirement of the cells derived from human dental pulp, which is the subject of ...
MR Baghaban Eslaminejad +3 more
doaj +1 more source
Zoo Biology, EarlyView.Peri‐apical masses were absent in both wild and semi‐wild Cape ground squirrels, despite dietary differences and minor incisor trauma. These findings suggest such lesions are rare outside captivity and not induced by low‐fiber diets alone, adding to the literature on environmental and dietary risk factors in elodont tooth pathology.
Quintin Norval +2 more
wiley +1 more source
What Outcomes Matter in Vital Pulp Therapy? Current Concepts and Challenges
Australian Dental Journal, EarlyView.ABSTRACT Vital pulp therapy (VPT) has re‐emerged as a practical and biologically sound alternative for managing deep caries and carious pulp exposures. Although its clinical use is now widespread, the outcomes used to judge the success of VPT remain inconsistent and often difficult to compare across studies.
Philip Yuan‐Ho Chien +5 more
wiley +1 more source
Biocompatibility With Osteogenic Potential of Premixed Bioceramic Cements for Use in Apical Surgery
Australian Endodontic Journal, EarlyView.ABSTRACT This study investigated the biocompatibility and osteogenic potential of premixed bioceramic cements (PBCs)—CeraPutty, EndoCEM MTA Premixed, Well‐Root PT, and One‐Fil PT Injectable—as alternatives to mineral trioxide aggregate for retrograde filling in endodontic microsurgery.
Yesol Kim +5 more
wiley +1 more source
Origens da vascularização da polpa dentária: estudo in vivo [PDF]
, 2006 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Odontologia.Na tentativa de estudar a formação de vasos sanguíneos durante a formação dentária, examinou-se a expressão de marcadores ...
Ferreira, Cimara Fortes
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British Journal of Pharmacology, EarlyView.Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka +3 more
wiley +1 more source
Dental Pulp - the Source of Mesenchymal Stem Cells
, 2008 Objective: the study aimed to isolation of dental pulp stem cells (DPSC), determination of proliferative and differentiation potential and observation of morphological changes and viability of DPSC cultured in vitro.
J. Suchánek +3 more
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Cell Proliferation, EarlyView.DPSC‐IVs suppressed PI3K/AKT/mTOR signalling pathway by delivering PTEN to tumour cells, which reduced the expression of Bcl‐2 and elevated that of Bax. Meanwhile, DPSC‐IVs activated PINK1/Parkin mediated mitophagy, which further raised ROS levels.
Yu Luo +10 more
wiley +1 more source