Results 111 to 120 of about 21,805 (216)

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa, Mohamad Koohi‐Moghadam, Mingxin Hu, Hong Wang, Colman McGrath, Waruna Lakmal Dissanayaka   +5 more
wiley   +1 more source

Successful isolation, in vitro expansion and characterization of stem cells from Human Dental Pulp

Journal of Stem Cells and Regenerative Medicine, 2010
BACKGROUND: Recent studies have shown that mesenchymal stem cells isolated from post natal human dental pulp, (Dental pulp stem cells-DPSCs) which is from permanent teeth and SHED (stem cells from human exfoliated deciduous teeth),the Periodontal ...
Preethy SP, Srinivasan T, Tholcopiyan L, Thamaraikannan P, Srinivasan V, Murugan P, Manjunath S, Kannan TA, Shalini R, Sunil PM, Manikandhan R, Muthu MS, Abraham S   +12 more
doaj  

Distinct Microbiota and Functional Pathway Profiles Define Success and Failure in Regenerative Endodontic Treatment

International Endodontic Journal, EarlyView.
ABSTRACT Aim To characterize the intracanal microbiota and identify key microbial taxa and functional pathways associated with regenerative endodontic treatment (RET) outcomes. Methodology In this observational cohort study, 196 samples were collected at five time points from external tooth surfaces (T1, T4) and root canals (T2, T3, T5).
Leimarembi Devi Naorem, Alina Wikström, Peter Quach, Lokeshwaran Manoharan, Ronald Ordinola‐Zapata, Olena Rakhimova, Malin Brundin, Nelly Romani Vestman   +7 more
wiley   +1 more source

Proteomic Analysis of Stromal Cells Derived from the Dental Pulp of Human Exfoliated Deciduous Teeth

, 2010
Human dental pulp derived from exfoliated deciduous teeth has been described as a promising alternative source of multipotent stem cells. While these cells share certain similarities with mesenchymal stem-like cells (MSC) isolated from other tissues ...
Venalis, Algirdas,, Savickiene, Jurate,, Tunaitis, Virginijus,, Navakauskiene, Ruta,, Treigyte, Grazina,, Aldonyte, Ruta,, Magnusson, Karl-Eric,, Suriakaite, Kristina,, Jarmalaviciute, Akvile,, Navakauskas, Dalius,, Surovas, Andrejus,, Borutinskaite, Veronika,, Liutkevicius, Evaldas,, Matuzevicius, Dalius,, Pivoriunas, Augustas,   +14 more
core   +1 more source

Cellular Dynamics and Dentine Bridge Formation Following Direct Pulp Capping With MTA and Biodentine in a Murine Model

International Endodontic Journal, EarlyView.
ABSTRACT Aim Formation of a mineralized dentine bridge is the hallmark of successful direct pulp capping (DPC). Mineral trioxide aggregate (MTA) and Biodentine are widely used capping materials, but in vivo evidence comparing their regenerative potential remains inconclusive. This study used a controlled murine model to compare dentine bridge formation
Amnah Sajdeya, Joshua Milgram, Nurit Kot‐Limon, Itzhak Abramovitz, Amnon Sharir   +4 more
wiley   +1 more source

The potential therapeutic roles of dental pulp stem cells in spinal cord injury

Frontiers in Molecular Biosciences
Spinal cord injury (SCI) can lead to serious functional disorders, which have serious impacts on patients and society. The current traditional treatments of SCI are not effective the injured spinal cord is difficult to repair and regenerate.
Jing Fu, Wenjie Li, Tengfei Mao, Zaipeng Chen, Lili Lai, Jiachen Lin, Zhiqiang Nie, Yunkai Sun, Yanqin Chen, Qin Zhang, Xigong Li   +10 more
doaj   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Expression of high mobility group box 1 in inflamed dental pulp and its chemotactic effect on dental pulp cells

, 2014
High mobility group box 1 protein (HMGB1) is a chromatin protein which can be released extracellularly, eliciting a pro-inflammatory response and promoting tissue repair process.
Jiang, Hongwei, Zhang, Xufang, Huang, Yihua, Fan, Chen, Ling, Junqi, Gong, Qimei   +5 more
core   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

Conhecimento dos pós-graduandos em odontologia da Universidade Federal de Santa Catarina sobre células-tronco [PDF]

, 2012
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Novas perspectivas de estudo têm ocorrido com a descoberta das células-tronco (CT), por tratar-se de células reparadoras de órgãos e tecidos lesados ...
Trajano, Juliana Martins
core