Results 91 to 100 of about 6,028,836 (265)

Regenerative medicine in dental and oral tissues: Dental pulp mesenchymal stem cell

Padjadjaran Journal of Dentistry, 2016
Background. Regenerative medicine is a new therapeutic modality using cell, stem cell and tissue engineering technologies. Purpose. To describe the regenerative capacity of dental pulp mesenchymal stem cell. Review.
Janti Sudiono, Ciptadhi Tri Oka, Melanie S Djamil, Ferry Sandra   +3 more
doaj   +1 more source

Dental pulp stem cells as a promising model to study imprinting diseases

International Journal of Oral Science, 2022
Parental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are characterized by growth and metabolic issues starting from birth to adulthood. They are mainly due
Eloïse Giabicani, Aurélie Pham, Céline Sélénou, Marie-Laure Sobrier, Caroline Andrique, Julie Lesieur, Agnès Linglart, Anne Poliard, Catherine Chaussain, Irène Netchine   +9 more
doaj   +1 more source

Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products

Bioengineering, 2022
The teeth, made up of hard and soft tissues, represent complex functioning structures of the oral cavity, which are frequently affected by processes that cause structural damage that can lead to their loss.
Luis A. Costa, Noemi Eiro, Andrea Vaca, Francisco J. Vizoso   +3 more
doaj   +1 more source

Lineage-specific exosomes promote the odontogenic differentiation of human dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of microRNAs

Stem cell research & therapeutics, 2019
Exosomes derived from dental pulp stem cells (DPSCs) can be used as biomimetic tools to induce odontogenic differentiation of stem cells, but the regulatory mechanisms and functions of exosome-encapsulated microRNAs are still unknown.
Xiaoli Hu, Y. Zhong, Yu-wei Kong, Yanan Chen, Junming Feng, Jian-Mao Zheng   +5 more
semanticscholar   +1 more source

Therapeutic Potential of Dental Pulp Stem Cells According to Different Transplant Types

Molecules, 2021
Stem cells are unspecialised cells capable of perpetual self-renewal, proliferation and differentiation into more specialised daughter cells. They are present in many tissues and organs, including the stomatognathic system.
Tomasz Staniowski, Anna Zawadzka-Knefel, Katarzyna Skośkiewicz-Malinowska   +2 more
semanticscholar   +1 more source

Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules [PDF]

, 2023
BACKGROUND: Pulp damage can lead to dentinogenesis impairment, irreversible pulpitis, or pulp necrosis. Despite being the most used endodontic procedure to treat damaged pulp, root canal therapy only results in nonvital teeth which are prone to fractures
Sandra, Ferry, Lambertus, Reynaldo, Ichwan, Solachuddin Jauhari Arief, Sutanto, Andri, Dewi, Nurrani Mustika, Wulandari, Widya, Celinna, Maria, Ferry Sandra, Solachuddin Jauhari Arief Ichwan, Nurrani Mustika Dewi, Reynaldo Lambertus, Maria Celinna, Widya Wulandari, Andri Sutanto   +13 more
core   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Osteogenic differentiation of human dental pulp stem cells on β-tricalcium phosphate/poly (-lactic acid/caprolactone) three-dimensional scaffolds

Journal of Tissue Engineering, 2012
Functional tissue engineering for bone augmentation requires the appropriate combination of biomaterials, mesenchymal stem cells, and specific differentiation factors. Therefore, we investigated the morphology, attachment, viability, and proliferation of
Rashi Khanna-Jain, Bettina Mannerström, Annukka Vuorinen, George KB Sándor, Riitta Suuronen, Susanna Miettinen   +5 more
doaj   +1 more source

Fabrication of Dentin-Pulp-Like Organoids Using Dental-Pulp Stem Cells

Cells, 2020
We developed a novel dentin-pulp-like organoid. It has both stem-cell and odontoblast characteristics using a mesenchymal cell lineage of human dental-pulp stem cells (hDPSCs).
Sang Yun Jeong, Soonchul Lee, Woo-Hee Choi, J. Jee, Hyung-Ryong Kim, Jongman Yoo   +5 more
semanticscholar   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source