Space biomedicine‐oriented bioink and biomimetic blood‒brain barrier
Bioinks and bioprinting play a pivotal role in the successful delivery of cell models and the fabrication of tissue models for space biomedicine research. This study investigated the effects of hypergravity and vibration on two‐dimensional adherent cells and three‐dimensional embedded cells and provided methods for storing hybrid bioink and high ...
Ranran Yan +3 more
wiley +1 more source
Application Of Prp In Quiescence-Activation Dpscs
Aim or purpose: This study aims to analyze the key active components in PRP that regulate rest-activation. By detecting its impact on osteogenic differentiation of cells, this study provides new ideas for the in vitro culture of dental pulp stem cells ...
Xuancheng Wei
doaj +1 more source
Neural stem cells (NSCs) have a high potency for differentiation to neurons and glial cells for replacement of damaged cells and paracrine effects for the regeneration and remyelination of host axons.
Jieun Jung +4 more
doaj +1 more source
The interplay of dental pulp stem cells and endothelial cells in an injectable peptide hydrogel on angiogenesis and pulp regeneration in vivo [PDF]
Securing an adequate blood supply for the survival of cell transplants is critical for a successful outcome in tissue engineering. Interactions between endothelial and progenitor/stem cells are important for vascularization of regenerating tissue ...
Dissanayaka, WL +4 more
core +1 more source
Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li +5 more
wiley +1 more source
Study of the Major Components of the PluriNet Network Expression in Dental Pulp Stem Cells Isolated from Human Third Molar Teeth [PDF]
Objective: The objective of this study was to isolate and culture human dental pulp stemcells to study important stem cell markers in them.Materials and Methods: Dental stem cells were isolated from human pulp and culturedin alpha-modified eagle’s medium
Behnam Ebrahimi +4 more
doaj
The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration
Adequate vascularization, a restricting factor for the survival of engineered tissues, is often promoted by the addition of stem cells or the appropriate angiogenic growth factors.
Petra Hilkens +5 more
doaj +1 more source
Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Abu Kasim, N. H. +3 more
core +1 more source
Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu +12 more
wiley +1 more source
Human Dental Pulp Stem Cells: The Culture Optimization for Increased Growth [PDF]
Introduction: Dental pulp-derived mesenchymal stem cells (MSCs) have emerged as a promising tool for use in regenerative medicine. The in vitro growth kinetic and culture requirement of the cells derived from human dental pulp, which is the subject of ...
MR Baghaban Eslaminejad +3 more
doaj +1 more source

