Epigenetic regulation of dental pulp stem cells and its potential in regenerative endodontics
Regenerative endodontics (RE) therapy means physiologically replacing damaged pulp tissue and regaining functional dentin–pulp complex. Current clinical RE procedures recruit endogenous stem cells from the apical papilla, periodontal tissue, bone marrow ...
Ying Liu+6 more
semanticscholar +1 more source
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira+7 more
wiley +1 more source
Mechanically-driven Stem Cell Separation in Tissues caused by Proliferating Daughter Cells [PDF]
The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth, the regulatory mechanisms, both cell-intrinsic and collective, which ensure tissue steady-state are still poorly ...
arxiv +1 more source
Early Osteogenic Differentiation Stimulation of Dental Pulp Stem Cells by Calcitriol and Curcumin
Curcumin, as a natural phenolic substance, is extracted from the rhizome of Curcuma longa (turmeric), which is effective in bone healthfulness. Calcitriol is an effective hormone in regulating bone remodeling and mineral homeostasis and immune response ...
M. Samiei+3 more
semanticscholar +1 more source
Influence of different types of pulp treatment during isolation in the obtention of human dental pulp stem cells [PDF]
Background: Different methods have been used in order to isolate dental pulp stem cells. The aim of this study was to study the effect of different types of pulp treatment during isolation, under 3% O 2 conditions, in the time needed and the efficacy ...
Borrás Blasco, Consuelo+5 more
core +1 more source
Therapeutic Potential of Dental Pulp Stem Cells According to Different Transplant Types
Stem cells are unspecialised cells capable of perpetual self-renewal, proliferation and differentiation into more specialised daughter cells. They are present in many tissues and organs, including the stomatognathic system.
Tomasz Staniowski+2 more
semanticscholar +1 more source
Mechanical Signaling in Dental Pulp Stem Cells
Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cells derived from dental pulp that serves as an important model for investigating biological regeneration. DPSCs have a multipotent differentiation capacity and can promote different biological processes, including osteogenesis, odontogenesis, chondrogenesis, and angiogenesis.
Wei Du+4 more
openaire +3 more sources
Fabrication and Bioactivity of Peptide‐Conjugated Biomaterial Tissue Engineering Constructs
Various fabrication techniques can be used to form tissue engineering constructs. These constructs can be conjugated with peptides in a straightforward fashion providing them with bioactivity. Peptides afford distinct advantages over other techniques for imparting bioactivity making peptide‐conjugated constructs excellent candidates to improve healing ...
Nicholas Nun, Abraham Joy
wiley +1 more source
Distal C terminus of CaV1.2 channels plays a crucial role in the neural differentiation of dental pulp stem cells. [PDF]
L-type voltage-dependent CaV1.2 channels play an important role in the maintenance of intracellular calcium homeostasis, and influence multiple cellular processes.
Jianping Ge+6 more
doaj +1 more source
The Migration and the Fate of Dental Pulp Stem Cells
Human dental pulp stem cells (hDPSCs) are adult mesenchymal stem cells (MSCs) obtained from dental pulp and derived from the neural crest. They can differentiate into odontoblasts, osteoblasts, chondrocytes, adipocytes and nerve cells, and they play a role in tissue repair and regeneration.
openaire +4 more sources