Results 41 to 50 of about 109,219 (372)

Epigenetic regulation of dental pulp stem cells and its potential in regenerative endodontics

open access: yesWorld Journal of Stem Cells, 2021
Regenerative endodontics (RE) therapy means physiologically replacing damaged pulp tissue and regaining functional dentin–pulp complex. Current clinical RE procedures recruit endogenous stem cells from the apical papilla, periodontal tissue, bone marrow ...
Ying Liu   +6 more
semanticscholar   +1 more source

Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia

open access: yesJBMR Plus, Volume 7, Issue 1, January 2023., 2023
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira   +7 more
wiley   +1 more source

Mechanically-driven Stem Cell Separation in Tissues caused by Proliferating Daughter Cells [PDF]

open access: yesSciPost Phys. 16, 097 (2024), 2023
The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth, the regulatory mechanisms, both cell-intrinsic and collective, which ensure tissue steady-state are still poorly ...
arxiv   +1 more source

Early Osteogenic Differentiation Stimulation of Dental Pulp Stem Cells by Calcitriol and Curcumin

open access: yesStem Cells International, 2021
Curcumin, as a natural phenolic substance, is extracted from the rhizome of Curcuma longa (turmeric), which is effective in bone healthfulness. Calcitriol is an effective hormone in regulating bone remodeling and mineral homeostasis and immune response ...
M. Samiei   +3 more
semanticscholar   +1 more source

Influence of different types of pulp treatment during isolation in the obtention of human dental pulp stem cells [PDF]

open access: yes, 2016
Background: Different methods have been used in order to isolate dental pulp stem cells. The aim of this study was to study the effect of different types of pulp treatment during isolation, under 3% O 2 conditions, in the time needed and the efficacy ...
Borrás Blasco, Consuelo   +5 more
core   +1 more source

Therapeutic Potential of Dental Pulp Stem Cells According to Different Transplant Types

open access: yesMolecules, 2021
Stem cells are unspecialised cells capable of perpetual self-renewal, proliferation and differentiation into more specialised daughter cells. They are present in many tissues and organs, including the stomatognathic system.
Tomasz Staniowski   +2 more
semanticscholar   +1 more source

Mechanical Signaling in Dental Pulp Stem Cells

open access: yesFrontiers in Bioscience-Landmark, 2023
Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cells derived from dental pulp that serves as an important model for investigating biological regeneration. DPSCs have a multipotent differentiation capacity and can promote different biological processes, including osteogenesis, odontogenesis, chondrogenesis, and angiogenesis.
Wei Du   +4 more
openaire   +3 more sources

Fabrication and Bioactivity of Peptide‐Conjugated Biomaterial Tissue Engineering Constructs

open access: yesMacromolecular Rapid Communications, Volume 44, Issue 1, January 2023., 2023
Various fabrication techniques can be used to form tissue engineering constructs. These constructs can be conjugated with peptides in a straightforward fashion providing them with bioactivity. Peptides afford distinct advantages over other techniques for imparting bioactivity making peptide‐conjugated constructs excellent candidates to improve healing ...
Nicholas Nun, Abraham Joy
wiley   +1 more source

Distal C terminus of CaV1.2 channels plays a crucial role in the neural differentiation of dental pulp stem cells. [PDF]

open access: yesPLoS ONE, 2013
L-type voltage-dependent CaV1.2 channels play an important role in the maintenance of intracellular calcium homeostasis, and influence multiple cellular processes.
Jianping Ge   +6 more
doaj   +1 more source

The Migration and the Fate of Dental Pulp Stem Cells

open access: yesBiology, 2023
Human dental pulp stem cells (hDPSCs) are adult mesenchymal stem cells (MSCs) obtained from dental pulp and derived from the neural crest. They can differentiate into odontoblasts, osteoblasts, chondrocytes, adipocytes and nerve cells, and they play a role in tissue repair and regeneration.
openaire   +4 more sources

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