Results 81 to 90 of about 129,435 (304)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Bioprinting of three-dimensional dentin-pulp complex with local differentiation of human dental pulp stem cells [PDF]

, 2019
Numerous approaches have been introduced to regenerate artificial dental tissues. However, conventional approaches are limited when producing a construct with three-dimensional patient-specific shapes and compositions of heterogeneous dental tissue.
Han, Jonghyeuk, Jang, Il Ho, Kang, Hyun-Wook, Kim, Da Sol, Kim, Hyung-Ryong   +4 more
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Fogeredetű őssejtek izolálása és jellemzése = Isolation and characterisation of postnatal stem cells of dental origin [PDF]

, 2009
Kutatásainkhoz a K61543 kutatási pályázatmellé elnyertük a IN67250 nemzetközi kiegészítő támogatást is, így beszámolónk ezek összefoglaló zárójelentése.
Bernhard, Ganss, Burghardt, Beáta, Gera, István, Hermann, Péter, Kiss, Gábor, Predrag, Lekic, Somogyi-Ganss, Eszter, Sophia, Cheon, Varga, Gábor   +8 more
core  

ABCG2 Is a Selectable Marker for Enhanced Multilineage Differentiation Potential in Periodontal Ligament Stem Cells. [PDF]

, 2014
Periodontal ligament stem cells (PDLSCs) provide an important source for tissue regeneration and may become especially useful in the formation of osteogenic seeds.
Matula, Zsolt, Német, Katalin, Sarkadi, Balázs, Szabo, G., Szepesi, Áron, Szigeti, Anna, Uher, Ferenc, Várady, György   +7 more
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol

Nature Communications
Sac1 is a conserved phosphoinositide phosphatase, whose loss-of-function compromises cell and organism viability. Here, we employ acute auxin-inducible Sac1 degradation to identify its immediate downstream effectors in human cells.
Xin Zhou, Miesje M. van der Stoel, Shreyas Kaptan, Haoran Li, Shiqian Li, Maarit Hölttä, Helena Vihinen, Eija Jokitalo, Christoph Thiele, Olli Pietiläinen, Shin Morioka, Junko Sasaki, Takehiko Sasaki, Ilpo Vattulainen, Elina Ikonen   +14 more
doaj   +1 more source

Epithelial label-retaining cells are absent during tooth cycling in Salmo salar and Polypterus senegalus [PDF]

, 2016
The Atlantic salmon (Salmo salar) and African bichir (Polypterus senegalus) are both actinopterygian fish species that continuously replace their teeth without the involvement of a successional dental lamina.
Fjelldal, P.G., Hansen, T., Vandenplas, S., Willems, M., Witten, P.E.   +4 more
core  

Remineralization strategies in oral hygiene: a position paper of Italian Society of Oral Hygiene Sciences-S.I.S.I.O. working group [PDF]

, 2017
Background/Objective: The clinical conditions that lead to an alteration of the enamel structure are numerous. The diet high in sugars and acidifying substances, psychological stress that triggers parafunctional behaviors, the reduced intake of fiber ...
Acito, Giovanna, Bassignani, Jessica, Chiavistelli, Lorella, Cotellessa, Silvia, Fantozzi, Giulia, Iommiello, Alessia, Iommiello, Alessia, Nardi, Gianna Maria, Sabatini, Silvia, Sanavia, Consuelo, Tatullo, Marco   +10 more
core   +1 more source

Chorioallantoic membrane assay as model for angiogenesis in tissue engineering : focus on stem cells [PDF]

, 2020
Tissue engineering aims to structurally and functionally regenerate damaged tissues, which requires the formation of new blood vessels that supply oxygen and nutrients by the process of angiogenesis.
Bronckaers, Annelies, De Spiegelaere, Ward, Lambrichts, Ivo, Lo Monaco, Melissa, Merckx, Greet, Tay, Hanna, van Zandvoort, Marc   +6 more
core   +3 more sources