Results 91 to 100 of about 39,457 (305)
International Journal of Ophthalmology, 2014 AIM:To investigate the effect of 5-Aza-2’-deoxycytidine (5-Aza-CdR), a DNA methyltransferase (DNMT) inhibitor, on the growth and survival of the Chinese retinoblastoma (RB) cell line HXO-RB44.METHODS:The DNA methylation status of the Ras association ...
Ru Liu +6 more
doaj +1 more source
Effects of pretreatment of target cells with 5-aza-2′-deoxycytidine.
, 2016 (A) PL21 cells or PBMNCs from HLA-A*24:02-positive healthy donor were pretreated with 5-aza-2′-deoxycytidine for 72 hours, then evaluated for their sensitivity to lysis by PEPP2-specific CTLs. (B) Expression of HLA class I, HLA-DR, and PD-L1 was assessed
Hiroyuki Aburatani (162634) +11 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa +21 more
wiley +1 more source
, 2015 Blocking DNMT attenuated incision-induced mechanical hypersensitivity (A) and thermal sensitization (B). Animals received intraperitoneal injection of 5-Aza-2′-deoxycytidine (4 mg/kg) or vehicle (saline) 24h and 2h prior to incision and once daily for 3 ...
Yuan Sun (15554) +6 more
core +1 more source
A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates
Biotechnology and Bioengineering, EarlyView.Damm et al. report standardized enzymatic cascades for production of all canonical nucleoside triphosphates from the corresponding nucleosides, using kinase‐catalyzed phosphorylation from acetyl phosphate. Reactions afforded ∼ 100 mM product in near‐quantitative conversion.
Oliver T. Damm +3 more
wiley +1 more source
Structure-Function Relationship of Human deoxycytidine Kinase.
, 2010 Structure-Function Relationship of Human deoxycytidine ...
Saugata. Hazra (7957007)
core
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
PLoS ONE, 2013 Vitamin B12, a co-factor in methyl-group transfer, is important in maintaining DNA (deoxycytidine) methylation.
Eoin P Quinlivan +8 more
doaj +1 more source
Cell cycle regulation of deoxycytidine kinase Evidence for post-transcriptional control
, 1993 Deoxycytidine kinase enzyme activity and deoxycitidine kinase mRNA content were determined at different positions of the cell cycle in permanent cell lines.
Hengstschläger, Markus +5 more
core +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian +4 more
wiley +1 more source