Results 181 to 190 of about 55,224 (274)

Urinary Metabolomic Changes and Potential Exercise-Induced Muscle Damage Biomarkers Identification in Trained Young Males Following Acute Intermittent Rowing Training. [PDF]

Biosensors (Basel)
Cheng Y, Yi Y, Shi X, Bo S.
europepmc   +1 more source

A phase 1 study of ASTX727 plus talazoparib in patients with triple‐negative or hormone resistant/HER2‐negative metastatic breast cancer

Cancer, Volume 132, Issue 8, 15 April 2026.
Abstract Background Poly(adenosine diphosphate ribose) polymerase (PARP) is recruited to DNA damage sites along with epigenetic factors such as DNA methyltransferase 1 (DNMT1). Inhibitors of DNMT modulate reactive oxygen species (ROS)‐cyclic adenosine monophosphate (cAMP)/Protein Kinase A signaling and induce a “BRCAness phenotype” that further ...
Kathy D. Miller, Alexandra Thomas, Sandra Althouse, Yong Zang, Erin Conder, Ryan Burgos, Bryan P. Schneider, Tarah Ballinger, Emily Douglas, Katherine Ansley, H. Josh Jang, Woonbok Chung, Jean‐Pierre Issa, Kenneth P. Nephew, Feyruz V. Rassool   +14 more
wiley   +1 more source

Cytidine and dCMP Deaminases-Current Methods of Activity Analysis. [PDF]

Int J Mol Sci
Ligasová A, Horejšová M, Brumarová R, Friedecký D, Koberna K.   +4 more
europepmc   +1 more source

Emerging roles for the epigenetic modifiers PBRM1 SETD2 and BAP1 in clear cell renal cell carcinoma pathogenesis and prognosis beyond VHL. [PDF]

Discov Oncol
Jixiang B, Xin C, Xiaoxuan P, Mingli S, Jieru H, Shuhui W.   +5 more
europepmc   +1 more source

Deoxycytidine Analogue TAS-109 [PDF]

, 2020
openaire   +1 more source

ENO1-mediated deoxycytidine synthesis and gemcitabine resistance by stabilizing RRM2 in pancreatic cancer. [PDF]

Cell Death Dis
Li Y, Wang H, Chen L, Gong Y, Zheng D, Li F, Wu C, He Z, Yu C.   +8 more
europepmc   +1 more source

Targeting opportunities presented by the pyrimidine biosynthesis pathway in Mycobacterium tuberculosis: a brief review. [PDF]

Biochem Soc Trans
Alberti M, Miggiano R.
europepmc   +1 more source

Clinical application and drug resistance mechanism of gemcitabine. [PDF]

Front Cell Dev Biol
Zhang X, Qi B, Chen J.
europepmc   +1 more source

Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS. [PDF]

Int J Mol Sci
Liang L, González Molina LA, Jellema PG, van Faassen M, Otten LTA, Mennega KP, Hof IH, Dijck-Brouwer DAJ, Dolga AM, Rots MG, Niezen-Koning KE.   +10 more
europepmc   +1 more source

Targeting the Rift Valley Fever Virus Polymerase: Resistance Mechanisms and Structural Insights. [PDF]

ACS Infect Dis
Král' M, Das A, Kotačka T, Blahošová A, Liščáková V, Hodek J, Konvalinka J, Demo G, Kožíšek M.   +8 more
europepmc   +1 more source