Results 201 to 210 of about 34,947 (246)

Development of enzyme immunoassay of 2′-deoxycytidine

Journal of Pharmaceutical and Biomedical Analysis, 1997
In order to study 2'-deoxycytidine (2'-dCyd) as a possible prognostic marker in cancer chemotherapy, an enzyme immunoassay (EIA) was developed. 2'-dCyd as a hapten was succinylated and two omicron-monosuccinyl-2'-dCyd's were purified by high performance liquid chromatography and identified by mass spectrometry and 1H-NMR.
K, Omura, K, Hirose, M, Itoh, T, Akizawa, M, Yoshioka   +4 more
openaire   +2 more sources

Regulation of human deoxycytidine kinase expression

Advances in Enzyme Regulation, 1993
The human deoxycytidine kinase gene is a single copy gene and is comprised of seven exons that are spread over more than 34 kb of the genome. The 5'-flanking region is highly G/C rich and does not contain CAAT or TATA boxes. This region, when cloned into a recorder gene construct containing the chloramphenicol acetyltransferase gene, is capable of ...
B S, Mitchell, J J, Song, E E, Johnson, E, Chen, J S, Dayton   +4 more
openaire   +2 more sources

Electron Attachment to Microhydrated Deoxycytidine Monophosphate

The Journal of Physical Chemistry B, 2018
DNA constituents are effectively decomposed via dissociative electron attachment (DEA). However, the DEA contribution to radiation damage in living tissues is a subject of ongoing discussion. We address an essential question, how aqueous environment influences the DEA to DNA.
Jaroslav Kočišek, Barbora Sedmidubská, Suvasthika Indrajith, Michal Fárník, Juraj Fedor   +4 more
openaire   +3 more sources

Effect of Phosphorylation on Deoxycytidine Kinase Activity

2006
In contrast to deoxycytidine kinase from leukemic blasts7, the recombinant dCK is a poor substrate for protein kinase C. Protein kinase A effectively phosphorylates the recombinant dCK. However, neither substrate specificity, nor kinetic parameters of dCK were changed upon phosphorylation.
T, Spasokoukotskaja, Z, Csapo, M, Sasvari-Szekely, S, Virga, I, Talianidis, S, Eriksson, M, Staub   +6 more
openaire   +2 more sources

Phosphorylation of 5-Halogenated Deoxycytidine Analogues by Deoxycytidine Kinase

Molecular Pharmacology, 1973
G M, Cooper, S, Greer
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Structure of 5-methyl-2'-deoxycytidine

Acta Crystallographica Section C Crystal Structure Communications, 1988
C10H15N3O4, Mr = 241.2, orthorhombic, P2(1)2(1)2(1), a = 10.454 (1), b = 11.922 (1), c = 9.057 (1) A, V = 1128.9 (1) A3, Z = 4, D chi = 1.419 Mg m-3, Cu K alpha radiation, lambda = 1.54178 A, mu = 0.95 mm-1, F(000) = 512, room temperature, R = 0.029 for 1186 observed reflections.
openaire   +2 more sources

Quinone Methide Alkylation of Deoxycytidine

The Journal of Organic Chemistry, 1997
Steven E., Rokita, Jianhong, Yang, Praveen, Pande, William A., Greenberg   +3 more
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Deoxycytidine Triphosphate

2021
openaire   +1 more source

Deoxycytidine: a morphine antagonist.

Archives internationales de pharmacodynamie et de therapie, 1978
Deoxycytidine antagonizes the analgesic action of morphine in the rat, morphine-induced respiratory depression in the rabbit and mitigates withdrawal in the dependent mouse. Administration of deoxycytidine does not precipitate the abstinence syndrome in dependent mice, a property shared by certain other endogenous morphine antagonsits.
openaire   +1 more source

Deoxycytidine kinase

1997
Dietmar Schomburg, Dörte Stephan
openaire   +1 more source