Results 191 to 200 of about 39,457 (305)

Lamin B1 safeguards the B cell genome and shapes lymphoma outcome

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Lamin B1 is a structural component of the nuclear lamina that participates in genome organization and transcriptional control. During adaptive immune responses, B lymphocytes in germinal centers (GCs) undergo clonal expansion and programmed DNA damage at immunoglobulin loci, while simultaneously downregulating Lamin B1.
Filip Filipsky, Katarina B. Chapman, Johannes Bloehdorn, Oscar Maiques, Abigail Lee, Andrew Clear, Jun Wang, John Gribben, Michael Hausmann, Christoph Cremer, Andrejs Braun, Marta C. Sallan, Tanya Klymenko   +12 more
wiley   +1 more source

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer. [PDF]

Oncol Lett
Nakamura M, Hagiwara T, Yamada K, Igari T, Fukumura Y, Saiura A, Takemura N, Kokudo N, Kawamura YI.   +8 more
europepmc   +1 more source

Transcript-Specific DNA Methylation Alterations of the RASSF1 Locus in Cancer Cells. [PDF]

Genes Chromosomes Cancer
Bermudez LG, Forigua CB, Ayala-Roldán CM, Romero JM, Ariza RR, Morales-Ruiz T, Roldán-Arjona T, Cañas A, Rojas A.   +8 more
europepmc   +1 more source

Frizzled-9 Expression Is Associated With Aggressive Clinicopathological Features and Reduced Overall Survival in Invasive Breast Carcinoma. [PDF]

Pathol Int
Bastos DR, Cintra RC, Longatto-Filho A, Termini L.   +3 more
europepmc   +1 more source

Precision Medicine in a Patient With Multiple Myeloma Presenting With t(2;11) and CCND1 Overexpression

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Translocations involving CCND1 are well described in multiple myeloma (MM), most frequently t(11;14), but rearrangements involving the immunoglobulin kappa (IGK) locus are rare. We present a case of a 71‐year‐old female with MM harboring t(2;11)(p11.2;q13), resulting in IGK::CCND1, with cyclin D1 and BCL‐2 overexpression.
Ariel Siegel, Chloe Ray, Meenakshi Mehrotra, Bruce Petersen, Sundar Jagannath, Samir Parekh, Jane Houldsworth, Hearn Jay Cho   +7 more
wiley   +1 more source

Urinary Metabolomic Changes and Potential Exercise-Induced Muscle Damage Biomarkers Identification in Trained Young Males Following Acute Intermittent Rowing Training. [PDF]

Biosensors (Basel)
Cheng Y, Yi Y, Shi X, Bo S.
europepmc   +1 more source

Cold Agglutinin Disease–Like Genetic Signatures in Lymphoplasmacytic Lymphoma–Like Cases Challenge the WHO Fifth Edition Classification

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background The fifth edition of the World Health Organization (WHO) classification defines cold agglutinin disease (CAD) as a clonal B‐cell lymphoproliferative disorder occurring in the absence of overt lymphoma, whereas cases associated with lymphoma are classified as cold agglutinin syndrome (CAS).
Yuki Sato, Daisuke Koyama, Shoki Yamada, Kengo Suzuki, Masahiko Fukatsu, Yuka Oka, Yuko Hashimoto, Takayuki Ikezoe   +7 more
wiley   +1 more source

Cytidine and dCMP Deaminases-Current Methods of Activity Analysis. [PDF]

Int J Mol Sci
Ligasová A, Horejšová M, Brumarová R, Friedecký D, Koberna K.   +4 more
europepmc   +1 more source

Progress and Challenges in Faba Bean Genetic Engineering

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Legumes are essential for global food security, serving as a vital source of plant‐based protein and playing a significant role in sustainable agricultural practices. Among legumes, faba bean (Vicia faba L.) is noteworthy due to its high‐protein content, broad climate adaptation, and suitability for cultivation in temperate regions.
Simone A. Gierlich, Thilani B. Jayakody, Sruthy Maria Augustine, Huijun Liu, Marko Jääskeläinen, Triin Vaisalu, Rod. J. Snowdon, Stig U. Andersen   +7 more
wiley   +1 more source

Emerging roles for the epigenetic modifiers PBRM1 SETD2 and BAP1 in clear cell renal cell carcinoma pathogenesis and prognosis beyond VHL. [PDF]

Discov Oncol
Jixiang B, Xin C, Xiaoxuan P, Mingli S, Jieru H, Shuhui W.   +5 more
europepmc   +1 more source