Results 141 to 150 of about 25,107 (224)

Acquired Resistance to Decitabine Associated with the Deoxycytidine Kinase A180P Mutation: Implications for the Order of Hypomethylating Agents in Myeloid Malignancies Treatment. [PDF]

Int J Mol Sci
Simonicova K, Janotka L, Kavcova H, Borovska I, Sulova Z, Breier A, Messingerova L.   +6 more
europepmc   +1 more source

[18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity. [PDF]

Proc Natl Acad Sci U S A, 2016
Kim W, Le TM, Wei L, Poddar S, Bazzy J, Wang X, Uong NT, Abt ER, Capri JR, Austin WR, Van Valkenburgh JS, Steele D, Gipson RM, Slavik R, Cabebe AE, Taechariyakul T, Yaghoubi SS, Lee JT, Sadeghi S, Lavie A, Faull KF, Witte ON, Donahue TR, Phelps ME, Herschman HR, Herrmann K, Czernin J, Radu CG.   +27 more
europepmc   +1 more source

Hypoxia-induced deoxycytidine kinase contributes to epithelial proliferation in pulmonary fibrosis. [PDF]

Am J Respir Crit Care Med, 2014
Weng T, Poth JM, Karmouty-Quintana H, Garcia-Morales LJ, Melicoff E, Luo F, Chen NY, Evans CM, Bunge RR, Bruckner BA, Loebe M, Volcik KA, Eltzschig HK, Blackburn MR.   +13 more
europepmc   +1 more source

Effect of staurosporine and ucn-01 on gemcitabine cytotoxicity in relation to cell cycle effects and p53 status [PDF]

, 2012
Abratt RP, Akinaga S, Akiyama T, Bergman AM, Bergman AM, Braakhuis BJ, Byrd JC, Harvey S, Heinemann V, Keepers YP, Kroep JR, Patel V, Plunkett W, Shao RG, Shi Z, Zhou XY   +15 more
core   +2 more sources

Deoxycytidine kinase expression underpins response to gemcitabine in bladder cancer. [PDF]

Clin Cancer Res, 2014
Kerr M, Scott HE, Groselj B, Stratford MR, Karaszi K, Sharma NL, Kiltie AE.   +6 more
europepmc   +1 more source

Structure-function studies of mammalian deoxycytidine kinases

, 2003
The major pathway for biosynthesis of DNA precursors is via the reduction of ribonucleosides to deoxyribonucleosides by the ribonucleotide reductase enzyme system which occurs in all proliferating cells. As a complement to this is de novo synthesis pathway where most cells express deoxyribonucleoside kinases.
openaire   +1 more source

Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. [PDF]

J Med Chem, 2014
Nomme J, Li Z, Gipson RM, Wang J, Armijo AL, Le T, Poddar S, Smith T, Santarsiero BD, Nguyen HA, Czernin J, Alexandrova AN, Jung ME, Radu CG, Lavie A.   +14 more
europepmc   +1 more source

Redesigning human 2'-deoxycytidine kinase enantioselectivity for L-nucleoside analogues as reporters in positron emission tomography. [PDF]

ACS Chem Biol, 2014
Muthu P, Chen HX, Lutz S.
europepmc   +1 more source

Regulation of phosphorylation of deoxycytidine and 2',2'-difluorodeoxycytidine (gemcitabine); effects of cytidine 5'-triphophate and uridine 5'-triphophate in relation to chemosensitivity for 2', 2'-difluorodeoxycytidine [PDF]

, 1996
Peters, G.J., Pinedo, H.M., Ruiz van Haperen, V.W.T., Veerman, G., Vermorken, J.B.   +4 more
core  

Clinicopathological significance of deoxycytidine kinase expression in esophageal squamous cell carcinoma. [PDF]

Mol Clin Oncol, 2013
Shimada Y, Okumura T, Sekine S, Moriyama M, Hojo S, Matsui K, Sawada S, Nagata T, Fukuoka J, Tsukada K.   +9 more
europepmc   +1 more source