Results 151 to 160 of about 14,531 (182)
Some of the next articles are maybe not open access.
Transcriptional and posttranscriptional regulation of deoxycytidine kinase
2021Η κινάση της δεοξυτιδίνης καταλύει τη φωσφορυλίωση της 2-δεοξυκυτιδίνης στην μονοφωσφορική της μορφή. Έχει βρεθεί να φωσφορυλιώνει μεγάλη ποικιλία υποστρωμάτων όπως δεοξυπουρίνες και δεοξυπυριμιδίνες. Η κυνάση αυτή είναι επίσης υπεύθυνη για την αρχική ενεργοποίηση ενός μεγάλου αριθμού κλινικά σημαντικών αναλόγων των νουκλεοσιδίων που χρησιμοποιούνται ...
openaire +2 more sources
1998
Deoxycytidine kinase (dCK) and deaminase (dCDA) are as activating and inactivating enzymes, respectively, in the metabolism of several chemotherapeutically important deoxynucleoside analogues [1]. 2′2′-Difluorodeoxycytidine (dFdC; gemcitabine) has considerable antitumor activity against solid tumors, such as against the chemoresistant non-small cell ...
J R, Kroep +9 more
openaire +2 more sources
Deoxycytidine kinase (dCK) and deaminase (dCDA) are as activating and inactivating enzymes, respectively, in the metabolism of several chemotherapeutically important deoxynucleoside analogues [1]. 2′2′-Difluorodeoxycytidine (dFdC; gemcitabine) has considerable antitumor activity against solid tumors, such as against the chemoresistant non-small cell ...
J R, Kroep +9 more
openaire +2 more sources
Phosphorylation of 5-Halogenated Deoxycytidine Analogues by Deoxycytidine Kinase
Molecular Pharmacology, 1973G M, Cooper, S, Greer
openaire +2 more sources
Kinetics of phosphorylation of 5-aza-2′-deoxycytidine by deoxycytidine kinase
Biochemical Pharmacology, 1979L. Richard, null Momparler, David Derse
openaire +2 more sources
The Role of Deoxycytidine Kinase in Gemcitabine Cytotoxicity
2002C L, van der Wilt +9 more
openaire +2 more sources
Haplotyping of the deoxycytidine kinase gene by multicapillary electrophoresis
Analytical Biochemistry, 2006Eszter, Szantai +3 more
openaire +2 more sources