Functionalized Nanogap for DNA Read‐Out: Nucleotide Rotation and Current‐Voltage Curves
ChemPhysChem, Volume 21, Issue 18, Page 2068-2074, September 15, 2020., 2020 An applied voltage bias across a nanogap opened by diamondoid‐functionalized electrodes can be used to detect the identity of DNA nucleotides. For the detection, the different rotations of the DNA inside the nanogap control the exact value of the electronic current used for the detection.
Frank C. Maier, Maria Fyta
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Transfection with thymidine kinase permits bromodeoxyuridine labelling of DNA replication in the human malaria parasite Plasmodium falciparum [PDF]
, 2015 Background Plasmodium falciparum, the causative agent of severe human malaria, is an early-diverging protozoan whose lifecycle has many unusual features, including its modes of replication.
Merrick, CJ
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New Phytologist, Volume 225, Issue 1, Page 234-249, January 2020., 2020 Summary Brown algae have convergently evolved plant‐like body plans and reproductive cycles, which in plants are controlled by differential DNA methylation. This contribution provides the first single‐base methylome profiles of haploid gametophytes and diploid sporophytes of a multicellular alga. Although only c.
Xiao Fan +14 more
wiley +1 more source
Mathematical Modelling of the Molecular Mechanisms of Interaction of Tenofovir with Emtricitabine against HIV [PDF]
, 2021 The combination of the two nucleoside reverse transcriptase inhibitors (NRTI) tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) is used in most highly active antiretroviral therapies for treatment of HIV-1 infection, as well as in pre-exposure ...
Iannuzzi, Sara, von Kleist, Max
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Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications. [PDF]
, 2015 Methylation of cytosine deoxynucleotides generates 5-methylcytosine (m(5)dC), a well-established epigenetic mark. However, in higher eukaryotes much less is known about modifications affecting other deoxynucleotides. Here, we report the detection of N(6)-
A Morgulis +44 more
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transcription profiling of 3D7: assignment of cytoadherent phenotypes to dominant transcripts [PDF]
, 2008 Background Cytoadherence of Plasmodium falciparum -infected red blood cells is mediated by var gene-encoded P. falciparum erythrocyte membrane protein-1 and host receptor preference depends in most cases on which of the 50–60 var genes ...
Gölnitz, Uta +2 more
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Functionalized nanogap for DNA read‐out : nucleotide rotation and current‐voltage curves [PDF]
, 2023 Functionalized nanogaps embedded in nanopores show a strong potential for enhancing the detection of biomolecules, their length, type, and sequence.
Fyta, Maria, Maier, Frank C.
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Comparative analysis of nucleotide translocation through protein nanopores using steered molecular dynamics and an adaptive biasing force. [PDF]
, 2014 The translocation of nucleotide molecules across biological and synthetic nanopores has attracted attention as a next generation technique for sequencing DNA.
Martin, HS, Jha, S, Coveney, PV
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Insights into the Conformation of Aminofluorene-Deoxyguanine Adduct in a DNA Polymerase Active Site [PDF]
, 2013 The active site conformation of the mutagenic fluoroaminofluorene-deoxyguanine adduct (dG-FAF, N-(2′-deoxyguanosin-8-yl)-7-fluoro-2-aminofluorene) has been investigated in the presence of Klenow fragment of Escherichia coli DNA polymerase I (Kfexo−) and ...
Beard, William A. +5 more
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A Role for Antisense Transcripts in Regulation of Viral Gene Expression [PDF]
, 2008 College of Arts and Sciences Undergraduate Research Scholarship recipient, College of Biological Sciences Dean's Undergraduate Research Fund recipientHuman cytomegalovirus (HCMV) infections are prevalent in human populations and may engender serious ...
Sivulich, Mary
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