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Studies on the metabolism of deoxynivalenol in the rat
Food and Chemical Toxicology, 1987The metabolism and tissue distribution of [14C]deoxynivalenol have been studied in male PVG rats. Following administration of a single oral 10-mg/kg dose, radioactivity excreted in the urine and faeces accounted, respectively, for 25 and 64% of the administered dose within 96 hr. Less than 0.15% of the dose was detected in the respired air. Very little
D.L. Bayley +10 more
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Deoxynivalenol in cereals in Russia
Toxicology Letters, 2004A survey of the occurrence of deoxynivalenol (DON) and zearalenone (ZEN) in wheat, rye, barley and maize harvested in 1989-2001 in several regions of Russia has been conducted. A total of 5652 samples of cereals were analysed for DON and ZEN by using TLC and normal-phase HPLC with UV-detector.
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An epimer of deoxynivalenol: purification and structure identification of 3-epi-deoxynivalenol
Food Additives & Contaminants: Part A, 2015In an investigation of deoxynivalenol (DON)-transformation products by Devosia mutans 17-2-E-8, the major product was identified as 3-epi-DON. This DON-transformation product was analysed by liquid chromatography and identified by congruent retention time and UV/Vis spectrum, as well as mass spectrometric data.
Ting Zhou +5 more
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Journal of Agricultural and Food Chemistry, 2013
Reduction of the Fusarium mycotoxin deoxynivalenol (DON) in animal feed by treatment with sodium bisulfite and sodium metabisulfite has been successfully demonstrated in several studies. All of them reported formation of one DON sulfonate of strongly reduced toxicity compared to DON. The starting point of the present work was investigation of different
Elisavet Kunz-Vekiru +7 more
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Reduction of the Fusarium mycotoxin deoxynivalenol (DON) in animal feed by treatment with sodium bisulfite and sodium metabisulfite has been successfully demonstrated in several studies. All of them reported formation of one DON sulfonate of strongly reduced toxicity compared to DON. The starting point of the present work was investigation of different
Elisavet Kunz-Vekiru +7 more
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Toxicological Sciences, 2020
Previously, researchers have demonstrated that mycotoxin deoxynivalenol significantly enhances immunocyte activation. However, the interaction between deoxynivalenol exposure and immune disorders remains unclear.
Toa Ookawara +9 more
semanticscholar +1 more source
Previously, researchers have demonstrated that mycotoxin deoxynivalenol significantly enhances immunocyte activation. However, the interaction between deoxynivalenol exposure and immune disorders remains unclear.
Toa Ookawara +9 more
semanticscholar +1 more source
Deoxynivalenol in grain and grain products
Mycotoxin Research, 2000• The results are intermediate data. Investigations have not yet been completed.• Grain and grain products contain different quantities of DON.• The main cause for DON infection is contamination of the grain during the growing season.• DON may also be produced during storage and/or handling and processing of food.• There does not seem to be a zero ...
U Waller +3 more
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Toxicokinetics and metabolism of deoxynivalenol in animals and humans
Archives of Toxicology, 2022Yu Sun +5 more
semanticscholar +1 more source
Mycotoxin Research, 1990
Three wheat samples collected in 1987 in Central Poland and naturally infected withFusarium spp were analyzed for the presence ofFusarium spp andFusarium toxins. Heads were separated into three fractions: kernels with visibleFusarium damage, healthy looking kernels, and chaff + rachis.The samples contained deoxynivalenol (2.0 - 40.0μg/g), nivalenol (O ...
Piotr Goliński +4 more
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Three wheat samples collected in 1987 in Central Poland and naturally infected withFusarium spp were analyzed for the presence ofFusarium spp andFusarium toxins. Heads were separated into three fractions: kernels with visibleFusarium damage, healthy looking kernels, and chaff + rachis.The samples contained deoxynivalenol (2.0 - 40.0μg/g), nivalenol (O ...
Piotr Goliński +4 more
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Phytotoxicity of deoxynivalenol to wheat calli
Mycotoxin Research, 1991The main objective of this study was to determine the toxicity of DON (deoxynivalenol) in wheat tissue culture after two weeks of contact. It was observed that increase of toxin concentration in medium caused decrease of regeneration ability of the calli. Three tested genotypes showed different sensitivity to 25 ppm of DON.
Janusz Zimny, I. Menke-Milczarek
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