Results 21 to 30 of about 192,494 (228)

Structure of acid deoxyribonuclease [PDF]

open access: yesNucleic Acids Research, 2017
Deoxyribonuclease II (DNase II) is also known as acid deoxyribonuclease because it has optimal activity at the low pH environment of lysosomes where it is typically found in higher eukaryotes. Interestingly, DNase II has also been identified in a few genera of bacteria and is believed to have arisen via horizontal transfer.
Varela-Ramirez, Armando   +6 more
openaire   +2 more sources

Bronchopleural communication following intrapleural doses of tPA/DNase for empyema

open access: yesRespirology Case Reports, 2020
Intrapleural tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) therapy is a new treatment for pleural infection. Clinical experiences of tPA/DNase therapy, and its complications, are cumulating.
Bapti Roy   +3 more
doaj   +1 more source

INCIDENCE OF BACILLUS CEREUS IN SOME FOOD STUFFS WITH THE SPECIAL REFERENCE TO ITS PRODUCTION OF THERMONUCLEASE ENZYME IN ASSIUT CITY [PDF]

open access: yesAssiut Veterinary Medical Journal, 1997
samples of meat and milk products (40 total of 200 random A samples of lunchoen, susage, kareish cheese, ice cream and yoghurt) The samples were examined Assiut city.
NAWAL GH, KHALIL
doaj   +1 more source

Detection of some virulence factors in Pseudomonas aeruginosa associated with diarrhea in Kirkuk City [PDF]

open access: yesKirkuk Journal of Science, 2015
Background: studies have shown that Pseudomonas aeruginosa can be a potential cause of antibiotic associated diarrhea. Pathogenesis based on endotoxin, exotoxins, and enzymes.
Siham Sh. AL-Salihi, Abbas Y. Hasan
doaj   +1 more source

Pharmacological Activation of cGAS for Cancer Immunotherapy

open access: yesFrontiers in Immunology, 2021
When compartmentally mislocalized within cells, nucleic acids can be exceptionally immunostimulatory and can even trigger the immune-mediated elimination of cancer.
Kyle M. Garland   +15 more
doaj   +1 more source

Effect of SARS-CoV-2 Infection and COVID-19 Vaccination on Oxidative Status of Human Placenta: A Preliminary Study

open access: yesAntioxidants, 2023
Infection with SARS-CoV-2 during pregnancy increases the risk of pregnancy complications associated with inflammation, which could lead to oxidative stress in the placenta. Whether vaccination against COVID-19 has any effect is unclear.
Kristína Macáková   +5 more
doaj   +1 more source

A Comparison of the Initial Actions of Spleen Deoxyribonuclease and Pancreatic Deoxyribonuclease

open access: yesJournal of Biological Chemistry, 1965
The modes of action of several deoxyribonucleases have been studied in varying detail. The manner in which pancreatic deoxyribonuclease degrades deoxyribonucleic acid has been thoroughly analyzed both with regard to the breakdown of secondary structure and to the products formed.
E T, YOUNG, R L, SINSHEIMER
openaire   +2 more sources

Immunothrombosis and Complement Activation Contribute to Disease Severity and Adverse Outcome in COVID-19

open access: yesJournal of Innate Immunity, 2023
Severe COVID-19 is characterized by systemic inflammation and multiple organ dysfunction syndrome (MODS). Arterial and venous thrombosis are involved in the pathogenesis of MODS and fatality in COVID-19.
Tiphaine Ruggeri   +9 more
doaj   +1 more source

Use of recombinant human deoxyribonuclease in pediatric intensive care unit – a single-center experience

open access: yesRevista Paulista de Pediatria, 2021
Objective: Dornase alfa (rhDNase) reduces the viscosity of purulent sputum in the lungs. The use in patients with cystic fibrosis (CF) is proven. However, the evidence of its applicability to other conditions is limited.
Daniel Meireles   +6 more
doaj   +2 more sources

Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models.

open access: yesPLoS Genetics, 2022
Urinary cell-free DNA (ucfDNA) is a potential biomarker for bladder cancer detection. However, the biological characteristics of ucfDNA are not well understood.
Meihui Chen   +18 more
doaj   +1 more source

Home - About - Disclaimer - Privacy