Results 71 to 80 of about 170,315 (251)

Circulating Level of Neutrophil Extracellular Traps Is Not a Useful Biomarker for Assessing Disease Activity in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. [PDF]

PLoS ONE, 2016
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of life-threatening disorders, and frequently affects the kidneys.
Huan Wang, Li-Li Sha, Tian-Tian Ma, Lu-Xia Zhang, Min Chen, Ming-Hui Zhao   +5 more
doaj   +1 more source

Ultrafast enzymatic digestion of deoxyribonucleic acid in aqueous microdroplets for sequence discrimination and identification

QRB Discovery, 2021
We report the use of aqueous microdroplets to accelerate deoxyribonucleic acid (DNA) fragmentation by deoxyribonuclease I (DNase I), and we present a simple, ultrafast approach named DNA fragment mass fingerprinting to discriminate different DNA ...
Xiaoqin Zhong, Hao Chen, Richard N. Zare
doaj   +1 more source

Adipocyte fatty acid‐binding protein as a cerebrospinal fluid–accessible biomarker and druggable target in subarachnoid haemorrhage: Linking fatty acid dysregulation to microglial neuroinflammation

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
A‐FABP mediates neuroinflammation and exaggerates SAH outcomes: In response to SAH, elevated A‐FABP combines with fatty acids to promote microglia activation via the JAK2/STAT3 pathway, while simultaneously disrupting fatty acid metabolism. These dual effects exacerbate neuroinflammation and neurological deterioration, thereby contributing to adverse ...
Xingwu Liu, Shenquan Guo, Xin Feng, Hao Tian, Lei Jin, Boyang Wei, Wenchao Liu, Xin Zhang, Ran Li, Zhiyuan Zhu, Jingjing Kong, Xifeng Li, Lingling Shu, Chuanzhi Duan   +13 more
wiley   +1 more source

A Deoxyribonuclease from Calf Spleen: I Purification and Properties [PDF]

, 1957
The deoxyribonucleases1 of animal tissues are of two types which are readily distinguishable by the conditions necessary for activity on their substrate, DNA.
Koerner, James F., Sinsheimer, Robert L.
core  

Nanomedicine Strategies Against Biofilm‐Associated Infections: Advances, Challenges, and Translational Barriers

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah, Munthar Kadhim‐Abosaoda, Hayjaa Mohaisen‐Mousa, S. Renuka Jyothi, Priya Priyadarshini‐Nayak, J. Bethanney Janney, Gurjant Singh, Ashish Singh‐Chauhan, Manoj Kumar‐Mishra   +8 more
wiley   +1 more source

Roles of Alp and Prt Regulons in the Response of Pseudomonas aeruginosa to UV‐C Light

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Our results show that LexA‐regulated genes are the first to be induced after DNA damage, while autolysis functions controlled by the Alp system are the last. Death by UV is mediated primarily by Alp or Prt systems, depending on the Pseudomonas aeruginosa subline. ABSTRACT UV light is a well‐studied environmental DNA damaging agent.
Marina R. B. Fonseca, Renatta S. Oliveira, Henrique Kustor, Rubia R. L. Freitas, Enzo B. S. Mello, Cristina E. Alvarez‐Martinez, Rodrigo S. Galhardo   +6 more
wiley   +1 more source

A Sub-cellular Localization of the Gene Product of the DNase-1 Locus in Drosophila melanogaster [PDF]

, 1980
A study was undertaken to determine the subcellular location of DNase-I, a major acid deoxyribonuclease in Drosophila melanogaster. Embryonic tissue used in these experiments was derived from a wild type strain and from a strain homozygous at the DNase-l
Detwiler, Charles, MacIntyre, R. J.
core   +1 more source

Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK‐ULK1‐Mediated Mitochondrial Quality Control

Aging Cell, Volume 25, Issue 2, February 2026.
Dietary protein restriction protects the aging heart in the context of obesity by limiting mitochondrial DNA leakage and suppressing cGAS–STING‐driven inflammation. Through AMPK–ULK1‐dependent mitophagy, protein restriction restores mitochondrial quality control, reduces cardiac remodeling, and preserves metabolic homeostasis during obesity‐associated ...
Wagner S. Dantas, Elizabeth R. M. Zunica, Elizabeth C. Heintz, Charles L. Hoppel, Cristal M. Hill, Christopher D. Morrison, Christopher L. Axelrod, Gangarao Davuluri, John P. Kirwan   +8 more
wiley   +1 more source

Fructan biosynthesis in Lolium perenne : tissue, cultivar and temperature effects on gene expression and protein accumulation profiles : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology at Massey University, Palmerston North, New Zealand [PDF]

, 2008
Cultivars of Lolium perenne with high concentrations of water soluble carbohydrates (WSCs) offer opportunities to mitigate greenhouse gas emissions (nitrous oxides) from grazed pastures and improve meat and milk production in livestock.
Xue, Hong
core  

Ферментативные активности сыворотки крови для диагностики и дифференциальной диагностики хронических диффузных заболеваний печени [PDF]

, 2019
ГЕПАТИТ ХРОНИЧЕСКИЙ /ДИАГНКРИПТОГЕННЫЙ ХРОНИЧЕСКИЙ ГЕПАТИТ /ДИАГНЦИРРОЗЫ ПЕЧЕНИ /ДИАГНФИБРОЗ ПЕЧЕНИ /ДИАГНГИАЛУРОНИДАЗНАЯ АКТИВНОСТЬТРИПСИНОПОДОБНАЯ АКТИВНОСТЬДЕЗОКСИРИБОНУКЛЕАЗНАЯ АКТИВНОСТЬЭЛАСТАЗНАЯ АКТИВНОСТЬДифференциальная диагностика хронического ...
Прищепенко, В. А.
core   +1 more source