Results 61 to 70 of about 14,551 (257)
Electrochemical Science Advances, EarlyView.ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley +1 more source
Codominance and toxins: A path to drugs of nearly unlimited selectivity [PDF]
, 1995 The effectiveness of drugs is often limited by their insufficient selectivity. I propose designs of therapeutic agents that address this problem. The key feature of these reagents, termed comtoxins (codominance-mediated toxins), is their ability to ...
Varshavsky, Alexander
core
Food Biomacromolecules, EarlyView.Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo +3 more
wiley +1 more source
In vitro antibacterial activity of crude medicinal plant extracts against ampicillin+penicillin-resistant Staphylococcus aureus [PDF]
, 2018 Staphylococcus aureus is the leading cause for foodborne diseases. Extensive use of antibiotics has led to emergence of antibiotic-resistant S. aureus.
Chern, Pei Ern +7 more
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Recombinant Human Deoxyribonuclease I [PDF]
, 2013 Human deoxyribonuclease I (DNase I) is an endonuclease that catalyzes the hydrolysis of extracellular DNA and is just one of the numerous types of nucleases found in nature. The enzymatic mechanism for a single turnover is reasonably well understood based on biochemical and structural studies that are consistent with divalent metal ion dependent ...
Robert A. Lazarus, Jeffrey S. Wagener
openaire +2 more sources
MXenes‐based flexible electronics for wound monitoring and treatment
Interdisciplinary Medicine, EarlyView.This article provides a comprehensive overview of recent advancements in MXenes‐based flexible electronic devices for wound monitoring. It discusses the monitoring mechanisms and values for various wound pathological parameters as well as their applications in treating bacterial infections and chronic wounds.
Ye Yang +6 more
wiley +1 more source
Generation, Mutagenesis, and Removal of Mini-F Sequences [PDF]
, 2012 Maintenance and manipulation of large DNA and RNA virus genomes had presented an obstacle for virological research. BAC vectors provided a solution to both problems as they can harbor large DNA sequences and can efficiently be modified using well ...
Kaufer, Benedikt B., Tischer, Karsten B.
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Medicinal Research Reviews, EarlyView.ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova +2 more
wiley +1 more source
Restriction-modification system with methyl-inhibited base excision and abasic-site cleavage activities [PDF]
, 2015 The restriction-modification systems use epigenetic modification to distinguish between self and nonself DNA. A modification enzyme transfers a methyl group to a base in a specific DNA sequence while its cognate restriction enzyme introduces breaks in ...
Fukuyo, Masaki +9 more
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Clinical &Experimental Allergy, EarlyView.Neutrophil activation in beta‐lactams (BL) immediate hypersensitivity reactions (IHR). Factor component analysis of IHR biomarkers suggests an IgG‐mediated mechanism. We propose Neutrophil Elastase as a biomarker of neutrophil activation in BL IHR. ABSTRACT Background Beta‐lactams (BLs) are the predominant cause of immediate allergic reactions to drugs.
Adrienne Astrid Gallizzi +13 more
wiley +1 more source