Results 61 to 70 of about 14,669 (270)

Roles of Alp and Prt Regulons in the Response of Pseudomonas aeruginosa to UV‐C Light

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Our results show that LexA‐regulated genes are the first to be induced after DNA damage, while autolysis functions controlled by the Alp system are the last. Death by UV is mediated primarily by Alp or Prt systems, depending on the Pseudomonas aeruginosa subline. ABSTRACT UV light is a well‐studied environmental DNA damaging agent.
Marina R. B. Fonseca, Renatta S. Oliveira, Henrique Kustor, Rubia R. L. Freitas, Enzo B. S. Mello, Cristina E. Alvarez‐Martinez, Rodrigo S. Galhardo   +6 more
wiley   +1 more source

Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK‐ULK1‐Mediated Mitochondrial Quality Control

Aging Cell, Volume 25, Issue 2, February 2026.
Dietary protein restriction protects the aging heart in the context of obesity by limiting mitochondrial DNA leakage and suppressing cGAS–STING‐driven inflammation. Through AMPK–ULK1‐dependent mitophagy, protein restriction restores mitochondrial quality control, reduces cardiac remodeling, and preserves metabolic homeostasis during obesity‐associated ...
Wagner S. Dantas, Elizabeth R. M. Zunica, Elizabeth C. Heintz, Charles L. Hoppel, Cristal M. Hill, Christopher D. Morrison, Christopher L. Axelrod, Gangarao Davuluri, John P. Kirwan   +8 more
wiley   +1 more source

The Enzymology and Genetics of Dna Repair in Drosophila Melanogaster (Ap Endonucleases, Oregon-R, Mus(2)201, Cleavage Mechanisms). [PDF]

, 1985
The work presented herein investigates the repair of apurinic/apyrimidinic (AP) sites in Drosophila melanogaster. Two different AP endonucleases were isolated differing in pH optima, reaction requirements, and associated activities.
Spiering, Andrea Lynn
core   +2 more sources

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

Salmonella Enteritidis–Induced Alteration of Inflammatory CXCL Chemokine Messenger-RNA Expression and Histologic Changes in the Ceca of Infected Chicks [PDF]

, 2008
To understand better the events in early avian host immune responses to Salmonella Enteritidis (SE), we examined messenger-RNA (mRNA) expression for eight genes: CXCLi1[K60], CXCLi2 [IL-8/CAF], interferon (IFN)-gamma, interleukin (IL)-1beta, IL-6, IL ...
Cheeseman, Jennifer, Kaiser, Pete, Lamont, Susan, Lamont, Susan, Levy, Nyssa, Lillehoj, Hyun   +5 more
core   +3 more sources

Effects of Concurrent Dosing on the Efficacy of Tissue Plasminogen Activator and Deoxyribonuclease in the Treatment of Pleural Infection [PDF]

, 2023
Vikas Pathak, Lukash Adhikari, Christine Zhou   +2 more
openalex   +1 more source

Bovine Pancreatic Deoxyribonuclease D

Journal of Biological Chemistry, 1974
Abstract Of the four deoxyribonucleases, DNases A, B, C, and D, observable by chromatography of preparations of the pancreatic enzyme on cellulose phosphate, DNase D, the component present in the smallest amount, has not been previously characterized. Peptide maps show that the sequence of the amino acid residues in the polypeptide chain of DNase D is ...
openaire   +2 more sources

Different deoxyribonucleases in human lymphocytes [PDF]

Nucleic Acids Research, 1974
The distribution pattern of deoxyribonuclease activities in human lymphocytes has been examined by micro-disc-electrophoresis. Four groups of deoxyribonuclease activities, differing in their electrophoretic mobility, in the nature of their optimal substrate and in their optimal incubation conditions, are characterized.
E J, Zöllner, W, Helm, R K, Zahn, J, Beck, M, Reitz   +4 more
openaire   +2 more sources

Enrichment of Hypermethylated DNA on Chip for Cervical Cancer Detection

Advanced Materials Interfaces, Volume 13, Issue 1, 7 January 2026.
A microfluidic chip coated with surface‐immobilized methyl binding domain 2 (MBD‐2) protein receptors, is able to bind hypermethylated DNA (hmDNA) from a cancer cell line selectively. Quantification by quantitative polymerase chain reaction (qPCR) shows a 30‐fold enrichment in cervical cancer target DNA.
Ruben W. Kolkman, Birgit M. M. Wever, Jeanne Elisabeth van Dongen, Annina P. van Splunter, Johan G. Bomer, Renske D. M. Steenbergen, Loes I. Segerink, Jurriaan Huskens   +7 more
wiley   +1 more source

Unlocking the therapeutic potential of tumor-derived EVs in ischemia-reperfusion: a breakthrough perspective from glioma and stroke

Journal of Neuroinflammation
Clinical studies have revealed a bidirectional relationship between glioma and ischemic stroke, with evidence of spatial overlap between the two conditions.
Zhongnan Hao, Wenxin Guan, Wei Wei, Meihua Li, Zhipeng Xiao, Qinjian Sun, Yongli Pan, Wenqiang Xin   +7 more
doaj   +1 more source