Results 71 to 80 of about 14,551 (257)

The Enzymology and Genetics of Dna Repair in Drosophila Melanogaster (Ap Endonucleases, Oregon-R, Mus(2)201, Cleavage Mechanisms). [PDF]

, 1985
The work presented herein investigates the repair of apurinic/apyrimidinic (AP) sites in Drosophila melanogaster. Two different AP endonucleases were isolated differing in pH optima, reaction requirements, and associated activities.
Spiering, Andrea Lynn
core   +2 more sources

Bovine Pancreatic Deoxyribonucleases A and C

Journal of Biological Chemistry, 1973
Abstract Peptide maps obtained with tryptic-chymotryptic hydrolysates of bovine pancreatic DNases A, B, and C show a high degree of similarity. The map for DNase C, however, shows one peptide to have moved to a significantly less basic position. The peptide in question was isolated from hydrolysates of A and C and its sequence determined in each ...
Johann Salnikow, Dagmar Murphy
openaire   +3 more sources

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

Development And Evaluation Of Terbutaline Sulphate Loaded-Biodegradable Microspheres For Pulmonary Delivery [PDF]

, 2007
Mikrosfera terbutalin sulfat (TBS) pelepasan tertahan dibangun menggunakan polimer PLA R 203H dan PLGA RG 504H. Sustained-release terbutaline sulphate (TBS) microspheres were developed using PLA R 203H and PLGA RG 504H ...
Mohammed Ahmed, Rehab Abdallah
core  

Salmonella Enteritidis–Induced Alteration of Inflammatory CXCL Chemokine Messenger-RNA Expression and Histologic Changes in the Ceca of Infected Chicks [PDF]

, 2008
To understand better the events in early avian host immune responses to Salmonella Enteritidis (SE), we examined messenger-RNA (mRNA) expression for eight genes: CXCLi1[K60], CXCLi2 [IL-8/CAF], interferon (IFN)-gamma, interleukin (IL)-1beta, IL-6, IL ...
Cheeseman, Jennifer, Kaiser, Pete, Lamont, Susan, Lamont, Susan, Levy, Nyssa, Lillehoj, Hyun   +5 more
core   +3 more sources

Capsular Type, Sequence Type and Microbial Resistance Factors Impact on DNase Activity of Streptococcus agalactiae Strains from Human and Bovine Origin [PDF]

, 2018
Extracellular deoxyribonucleases (DNases) contribute to the spread of pathogenic bacteria through the evasion from host innate immunity. Our main objective was to evaluate the production of extracellular DNases by human and bovine Streptococcus ...
Barroco, Cinthia Alves, Borrego, Maria José, Damião, Vera, Florindo, Carlos, Gomes, João Paulo, Santos-Sanches, Ilda, Silvestre, Inês, Spellerberg, Barbara   +7 more
core   +1 more source

Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation

The FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Chronic Polystyrene Microplastic (PS‐MP) Exposure Drives Hepatic Steatosis via Dual Inflammatory and Metabolic Pathways. Chronic PS‐MP exposure in C57BL/6N mice induces hepatic lipid deposition and elevated body fat through M1‐polarized Kupffer cells, IL‐17A/NF‐κB activation, and impaired lipid homeostasis.
Ting Li, Zhenghong Yao, Yuxin Huang, Ran Li, Lu Zhang, Rucheng Chen, Weijia Gu   +6 more
wiley   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

Advanced Science, Volume 12, Issue 33, September 4, 2025.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li, Ying Qu, Bingyang Chu, Tingkui Wu, Meng Pan, Dong Mo, Lang Li, Yang Ming, Yun Yang, Meng Wang, Xinlong He, Zhiyong Qian   +11 more
wiley   +1 more source

A comparison of a newly discovered invertebrate acid deoxyribonuclease with vertebrate deoxyribonuclease II [PDF]

, 1963
Thesis (Ph.D)--Boston UniversityCharacteristics of deoxyribonuclease II from calf thymus and spleen were described and verified by the following experimental procedures.
Russell, Anthony Post
core  

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Advanced Science, Volume 12, Issue 34, September 11, 2025.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source