Results 1 to 10 of about 81,856 (291)

Personalizing esketamine treatment in TRD and TRBD: the role of mentalization, cognitive rigidity, psychache, and suicidality [PDF]

Frontiers in Psychiatry
IntroductionTreatment-Resistant Depression (TRD) remains a major challenge in the management of Major Depressive Disorder (MDD). Esketamine, the S-enantiomer of ketamine and a glutamatergic modulator, was approved by the FDA and EMA for TRD in 2019 ...
Miriam Olivola, Miriam Olivola, Filippo Mazzoni, Barbara Tarantino, Alessandro Guffanti, Matteo Marcatili, Monica Macellaro, Monica Macellaro, Monica Macellaro, Nicolaja Girone, Nicolaja Girone, Nicolaja Girone, Vassilis Martiadis, Fabiola Raffone, Tiziano Prodi, Tiziano Prodi, Natascia Brondino, Giovanni Martinotti, Massimo Clerici, Massimo Clerici, Roberta Anniverno, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso, Bernardo Dell’Osso   +26 more
doaj   +2 more sources

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients

PLoS ONE, 2020
Objective The economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non–treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li, Ling Zhang, Allitia DiBernardo, Grace Wang, John J. Sheehan, Kwan Lee, Johan Reutfors, Qiaoyi Zhang, Fernando A. Wilson   +8 more
doaj   +2 more sources

Comparison of cognitive function in patients with treatment-resistant depression and drug-naive first-episode major depressive disorder

Sichuan jingshen weisheng, 2021
ObjectiveTo explore the differences of cognitive function in patients with treatment-resistant depression and drug-naive first-episode major depressive disorder， and to examine the relationship between severity of clinical symptoms and cognitive function，
Zheng Chaodun, Chen Yingmei, Tan Jiuwei, Liu Guoxiong, Cai Yinglian, Lan Xiaofeng, Zhou Yanling   +6 more
doaj   +1 more source

Increased Serum Levels of Oxytocin in 'Treatment Resistant Depression in Adolescents (TRDIA)' Group. [PDF]

PLoS ONE, 2016
'Treatment-resistant depression' is depression that does not respond to an adequate regimen of evidence-based treatment. Treatment-resistant depression frequently becomes chronic.
Tsuyoshi Sasaki, Kenji Hashimoto, Yasunori Oda, Tamaki Ishima, Madoka Yakita, Tsutomu Kurata, Masaru Kunou, Jumpei Takahashi, Yu Kamata, Atsushi Kimura, Tomihisa Niitsu, Hideki Komatsu, Tadashi Hasegawa, Akihiro Shiina, Tasuku Hashimoto, Nobuhisa Kanahara, Eiji Shimizu, Masaomi Iyo   +17 more
doaj   +1 more source

Resistance or pseudo-resistance?

European Psychiatry, 2022
Introduction Treatment-Resistant Depression continues to represent a great challenge for clinicians. Objectives We investigated patients with history of resistance, assessing prognostic factors, response to treatments, and remission over time ...
R. Zanardi, F. Attanasio, C. De Cesare, V. Fazio, C. Colombo   +4 more
doaj   +1 more source

Ketamine as Add-On Treatment in Psychotic Treatment-Resistant Depression

Brain Sciences, 2023
Psychotic treatment-resistant depression is a complex and challenging manifestation of mood disorders in the clinical setting. Psychotic depression is a subtype of major depressive disorder characterized by mood-consistent hallucinations and/or delusions.
Maria Gałuszko-Węgielnik, Zuzanna Chmielewska, Katarzyna Jakuszkowiak-Wojten, Mariusz S. Wiglusz, Wiesław J. Cubała   +4 more
doaj   +1 more source

Serum level of soluble interleukin 6 receptor is a useful biomarker for identification of treatment‐resistant major depressive disorder

Neuropsychopharmacology Reports, 2020
Aim A substantial proportion of major depressive disorder patients are treatment‐resistant to antidepressant therapy, who require augmentation drugs, or other treatments including electroconvulsive therapy or transcranial magnetic stimulation ...
Katsuhiko Yamasaki, Tomonori Hasegawa, Masatoshi Takeda   +2 more
doaj   +1 more source

The effectiveness of cognitive behavioral therapy on treatment-resistant depression

Chronic Diseases Journal, 2020
BACKGROUND: Treatment-resistant depression (TRD) is a severe and chronic form of major depression. It poses significant clinical, personal, and economic burden and does not respond to antidepressants. Psychotherapy can be a suggested option.
Rezvan Sadrmohammadi, Simin Gholamrezaei
doaj   +1 more source

Maintenance ECT in Recurrent Depression and Treatment Resistant Schizophrenia

Bezmiâlem Science, 2022
Objective:Electroconvulsive therapy (ECT) has been used for treatment of depression and psychosis for a long time. A less known way of use is as a maintenance treatment for keeping patients stable during remission. Recently ECT has been increasingly used
Sinem Zeynep METİN
doaj   +1 more source

Informed consent decision-making in deep brain stimulation [PDF]

, 2018
Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious.
Appelbaum, Bell, Berg, Gilbert, Grisso, Jahanshahi, Mehdorn   +6 more
core   +2 more sources