Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata [PDF]
MicrobiologyOpen, 2023 Lichens are symbiotic associations consisting of a photobiont (algae or cyanobacteria) and a mycobiont (fungus), which together generate a variety of unique secondary metabolites.
Nadim Ahmad +6 more
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Penicillides from Penicillium and Talaromyces: Chemical Structures, Occurrence and Bioactivities [PDF]
MoleculesPenicillide is the founder product of a class of natural products of fungal origin. Although this compound and its analogues have been identified from taxonomically heterogeneous fungi, they are most frequently and typically reported from the species of ...
Maria Michela Salvatore +3 more
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Brominated Depsidones with Antibacterial Effects from a Deep-Sea-Derived Fungus Spiromastix sp. [PDF]
Marine DrugsEleven new brominated depsidones, namely spiromastixones U-Z5 (1–11) along with five known analogues (12–16), were isolated from a deep-sea-derived fungus Spiromastix sp. through the addition of sodium bromide during fermentation.
Zequan Huang +7 more
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Extraction of lichen bioactive compounds using volatile natural deep eutectic solvents and comparative analytical approaches [PDF]
Scientific ReportsLichens are a source of bioactive secondary metabolites with different pharmacological activities. However, these metabolites are challenging regarding their extraction.
S. Dresler +9 more
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Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer’s disease [PDF]
Frontiers in PharmacologyBackground: The development of effective inhibitors that can inhibit amyloid β (Aβ) peptides aggregation and promote neurite outgrowth is crucial for the possible treatment of Alzheimer’s disease (AD).
Meixia Yang +15 more
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Bioproduction of Depsidones for Pharmaceutical Purposes [PDF]
, 2011 الأشنات هي تكافلات حميمة وطويلة الأجل محددة من الطحالب الضوئية أو البكتيريا الزرقاء والفطريات غيرية التغذية التي انضمت لتشكيل كيان بيولوجي جديد مختلف عن مكوناته الفردية (جالون وكارديش، 1995). ينتج الكلوروليكين بشكل أساسي مواد فينولية فريدة من نوعها، ديبيد، ديبسيدون وبعض ثنائي بنزوفيوران، مثل أحماض اليوزنيك (Huneck & Yoshimura، 1996)، التي لا تنتجها ...
Carlos Vicente +2 more
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Discovery of Fungus-Derived Nornidulin as a Novel TMEM16A Inhibitor: A Potential Therapy to Inhibit Mucus Secretion in Asthma [PDF]
Journal of Experimental Pharmacology, 2023 Pawin Pongkorpsakol,1,* Chantapol Yimnual,2,* Wilasinee Satianrapapong,3 Nichakorn Worakajit,4 Suchada Kaewin,2 Praphatsorn Saetang,5 Vatcharin Rukachaisirikul,5 Chatchai Muanprasat2 1Princess Srisavangavadhana College of Medicine, Chulabhorn ...
Pongkorpsakol P +7 more
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Natural Product Communications, 2012 Two depsides and five depsidones, isolated from lichens, were tested to determine their in vivo protective effects on tobacco leaves challenged with Tobacco Mosaic Virus (TMV).
Íngrid Ramirez +2 more
exaly +2 more sources
Lichen Depsidones with Biological Interest [PDF]
Planta Medica, 2021 AbstractDepsidones are some of the most abundant secondary metabolites produced by lichens. These compounds have aroused great pharmacological interest due to their activities as antioxidants, antimicrobial, and cytotoxic agents. Hence, this paper aims to provide up-to-date knowledge including an overview of the potential biological interest of lichen ...
Isabel, Ureña-Vacas +3 more
openaire +2 more sources
Separations, 2022 Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification ...
Beatriz Sepúlveda +4 more
doaj +1 more source