Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata [PDF]
MicrobiologyOpen, 2023 Lichens are symbiotic associations consisting of a photobiont (algae or cyanobacteria) and a mycobiont (fungus), which together generate a variety of unique secondary metabolites.
Nadim Ahmad +6 more
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Brominated Depsidones with Antibacterial Effects from a Deep-Sea-Derived Fungus Spiromastix sp. [PDF]
Marine DrugsEleven new brominated depsidones, namely spiromastixones U-Z5 (1–11) along with five known analogues (12–16), were isolated from a deep-sea-derived fungus Spiromastix sp. through the addition of sodium bromide during fermentation.
Zequan Huang +7 more
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Penicillides from Penicillium and Talaromyces: Chemical Structures, Occurrence and Bioactivities [PDF]
MoleculesPenicillide is the founder product of a class of natural products of fungal origin. Although this compound and its analogues have been identified from taxonomically heterogeneous fungi, they are most frequently and typically reported from the species of ...
Maria Michela Salvatore +3 more
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Phytochemical Profiling of Sticta caulescens De Not.: Green Extraction and Multiscale Chemotaxonomic Analysis [PDF]
PlantsThe aim of this research was to identify the wealth of secondary metabolites in the Chilean lichen Sticta caulescens, applying green chemistry approaches and comparing the following two extraction methods: (a) conventional maceration with methanol, and ...
Nicolás Cifuentes-Araya +7 more
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Extraction of lichen bioactive compounds using volatile natural deep eutectic solvents and comparative analytical approaches [PDF]
Scientific ReportsLichens are a source of bioactive secondary metabolites with different pharmacological activities. However, these metabolites are challenging regarding their extraction.
S. Dresler +9 more
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Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer’s disease [PDF]
Frontiers in PharmacologyBackground: The development of effective inhibitors that can inhibit amyloid β (Aβ) peptides aggregation and promote neurite outgrowth is crucial for the possible treatment of Alzheimer’s disease (AD).
Meixia Yang +15 more
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Marine Drugs, 2019 Six new depsidones, curdepsidones B−G (1−6), were obtained from the marine-derived fungus Curvularia sp. IFB-Z10. Their planar structures were determined by comprehensive analysis of HRESIMS and 1D/2D-NMR data.
Yi Ding +5 more
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New depsidones and isoindolinones from the mangrove endophytic fungus Meyerozyma guilliermondii (HZ-Y2) isolated from the South China Sea [PDF]
Beilstein Journal of Organic Chemistry, 2015 Three new depsidones, botryorhodines E–G (1–3), and two new isoindolinones, meyeroguillines A and B (7 and 9), along with five known compounds were isolated from an endophytic fungus Meyerozyma guilliermondii, derived from the mangrove plant Kandelia ...
Senhua Chen +5 more
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Discovery of Fungus-Derived Nornidulin as a Novel TMEM16A Inhibitor: A Potential Therapy to Inhibit Mucus Secretion in Asthma [PDF]
Journal of Experimental Pharmacology, 2023 Pawin Pongkorpsakol,1,* Chantapol Yimnual,2,* Wilasinee Satianrapapong,3 Nichakorn Worakajit,4 Suchada Kaewin,2 Praphatsorn Saetang,5 Vatcharin Rukachaisirikul,5 Chatchai Muanprasat2 1Princess Srisavangavadhana College of Medicine, Chulabhorn ...
Pongkorpsakol P +7 more
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Natural Product Communications, 2012 Two depsides and five depsidones, isolated from lichens, were tested to determine their in vivo protective effects on tobacco leaves challenged with Tobacco Mosaic Virus (TMV).
Íngrid Ramirez +2 more
exaly +2 more sources