Results 41 to 50 of about 1,299 (187)

Climate‐specific biosynthetic gene clusters in populations of a lichen‐forming fungus

Environmental Microbiology, Volume 23, Issue 8, Page 4260-4275, August 2021., 2021
Summary Natural products can contribute to abiotic stress tolerance in plants and fungi. We hypothesize that biosynthetic gene clusters (BGCs), the genomic elements that underlie natural product biosynthesis, display structured differences along elevation gradients.
Garima Singh, Anjuli Calchera, Meike Schulz, Moritz Drechsler, Helge B. Bode, Imke Schmitt, Francesco Dal Grande   +6 more
wiley   +1 more source

Protocetraric and Salazinic Acids as Potential Inhibitors of SARS-CoV-2 3CL Protease: Biochemical, Cytotoxic, and Computational Characterization of Depsidones as Slow-Binding Inactivators

Pharmaceuticals, 2022
The study investigated the inhibitory activity of protocetraric and salazinic acids against SARS-CoV-2 3CLpro. The kinetic parameters were determined by microtiter plate-reading fluorimeter using a fluorogenic substrate. The cytotoxic activity was tested
Lorenza Fagnani, Lisaurora Nazzicone, P. Bellio, N. Franceschini, D. Tondi, A. Verri, S. Petricca, R. Iorio, G. Amicosante, M. Perilli, G. Celenza   +10 more
semanticscholar   +1 more source

Effect of Extracts and their Depsidones on Micronucleus Distribution in Human Lymphocytes

Natural Product Communications, 2013
Three lichen depsidones, physodalic acid (1), physodic acid (2), and 3-hydroxy physodic acid (3), were isolated from Hypogymnia physodes diethyl ether extract using column chromatography, and their structures determined by comparing their UV, 1 H and 13 ...
Igor Ž. Stojanović, Miroslava Stanković, Olga Jovanović, Goran Petrović, Andrija Šmelcerovic, Gordana S. Stojanović   +5 more
doaj   +1 more source

Radical-scavenging Potential of Phenolic Compounds from Brazilian Lichens

Orbital: The Electronic Journal of Chemistry, 2015
Lichens produce a wide range of phenolic substances, mostly depsides and depsidones. As part of our ongoing study of lichens from the Cerrado biome in Mato Grosso do Sul state, the present article reports novel findings on the radical-scavenging ...
Neli Kika Honda, Thiago Inácio Barros Lopes, Rodrigo César da Silva Costa, Roberta Gomes Coelho, Nídia Cristiane Yoshida, Cristiane Regine Vieira Rivarola, Marcelo Pinto Marcelli, Adriano Afonso Spielmann   +7 more
doaj   +3 more sources

Anticancer Potential of Lichens’ Secondary Metabolites

Biomolecules, 2020
Lichens produce different classes of phenolic compounds, including anthraquinones, xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed effective biological activities such as antioxidant, antiviral, antibiotics, antifungal, and
Zuzana Solárová, Alena Liskova, Marek Samec, Peter Kubatka, Dietrich Büsselberg, Peter Solár   +5 more
doaj   +1 more source

Actividad antioxidante de los polifenoles de HYPOGYMNIA TAVARESII D. HAWKSW. & P. JAMES

Química Nova, 2016
Lichen substances have more than one phenolic hydroxyl group attached to one or more benzene rings, thus qualifying them as polyphenols. The secondary metabolites isolated from the lichen H.
Elsa M. Rodríguez Pérez, Francisco J. Toledo Marante, Josefa Caballero Hernández, Jaime Bermejo Barrera, Francisco J. Estevez Rosas   +4 more
doaj   +1 more source

Depsidone Derivatives and a Cyclopeptide Produced by Marine Fungus Aspergillus unguis under Chemical Induction and by Its Plasma Induced Mutant

Molecules, 2018
A new depsidone derivative (1), aspergillusidone G, was isolated from a marine fungus Aspergillus unguis, together with eight known depsidones (2‒9) and a cyclic peptide (10): agonodepside A (2), nornidulin (3), nidulin (4), aspergillusidone F (5 ...
Wen-Cong Yang, Hai-Yan Bao, Ya-Yue Liu, Ying-Ying Nie, Jing-Ming Yang, Peng-Zhi Hong, Yi Zhang   +6 more
doaj   +1 more source

Phylogenetic Studies and Metabolite Analysis of Sticta Species from Colombia and Chile by Ultra-High Performance Liquid Chromatography-High Resolution-Q-Orbitrap-Mass Spectrometry

Metabolites, 2022
Eleven species of lichens of the genus Sticta, ten of which were collected in Colombia (S. pseudosylvatica S. luteocyphellata S. cf. andina S. cf. hypoglabra, S. cordillerana, S. cf. gyalocarpa S. leucoblepharis, S. parahumboldtii S.
Laura Albornoz, Alfredo Torres-Benítez, Miguel Moreno-Palacios, Mario J. Simirgiotis, Saúl A. Montoya-Serrano, Beatriz Sepulveda, Elena Stashenko, Olimpo García-Beltrán, Carlos Areche   +8 more
doaj   +1 more source

The Role of Secondary Metabolites and Bark Chemistry in Shaping Diversity and Abundance of Epiphytic Lichens

Frontiers in Forests and Global Change, 2022
Diversity of secondary lichen metabolites was studied in epiphytic lichens on six phorophytes—spruce, pine, birch, alder, aspen and poplar in the Middle Urals of Russia. Atranorin, usnic, fumarprotocetraric acid, zeorin, and gyrophoric acid were found in
Alexander Paukov, Anzhelika Teptina, Alexander Ermoshin, Ekaterina Kruglova, Lada Shabardina   +4 more
doaj   +1 more source

Dereplicative Combination of HPLC/DAD/MS and 2D NMR to Identify Lichexanthone Isomers in Lichen Extracts

Phytochemical Analysis, Volume 37, Issue 2, Page 330-343, March 2026.
ABSTRACT Introduction Lichexanthones are the major xanthones found in lichens. They present a high degree of isomerism, which makes their identification tedious. Xanthones are known to occur in lichens according to chemosyndromes, and these compounds act as chemotaxonomic markers.
Solenn Ferron, Marylène Chollet‐Krugler, Hermann Pinson, Rania Marzoug, Philippe Uriac, Françoise Lohézic‐Le Dévéhat   +5 more
wiley   +1 more source