Results 201 to 210 of about 9,955 (253)

Biosynthesis of depsipeptide mycotoxins in Fusarium

European Journal of Plant Pathology, 2002
The cyclic hexadepsipeptide enniatin is known as a phytopathogenic compound from Fusaria causing necrosis and wilt. The molecule consists of three alternating residues each of a branched chain amino acid and D-hydroxyisovaleric acid (D-Hiv). Enniatins are synthesized by a 347kDa multienzyme (enniatin synthetase) via a thiol template mechanism.
Till Hornbogen, Mirko Glinski, Rainer Zocher   +2 more
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Cyclic Depsipeptides, Callipeltins

2020
Marine sponges are considered as an untapped reservoir of biologically active natural compounds exhibiting numerous interesting and potentially useful pharmacological activities, including antimicrobial, antifungal, cytotoxic, anti-inflammatory, and immunostimulatory activities.
Reda A. Abdelhamid, Hiroyuki Konno
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Xentrivalpeptides A–Q: Depsipeptide Diversification in Xenorhabdus

Journal of Natural Products, 2012
Seventeen depsipeptides, xentrivalpeptides A-Q (1-17), have been identified from an entomopathogenic Xenorhabdus sp. Whereas the structure of xentrivalpeptide A (1) was determined after its isolation by NMR spectroscopy and the advanced Marfey's method, the structures of all other derivatives were determined using a combination of stable isotope ...
Zhou, Q., Dowling, A., Heide, H., Wohnert, J., Brandt, U., Brandt, U., Baum, J., Ffrench-Constant, R., Bode, H.B.   +8 more
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Synthese geschützter Depsipeptide

Helvetica Chimica Acta, 1960
AbstractThe syntheses and properties of p‐nitrobenzyl diazoacetyl‐glycinate (VI), p‐nitrobenzyl p‐(p‐methoxyphenylazo)‐benzyloxycarbonyl‐glycyl‐glycollyl‐glycinate (II) and p‐nitrobenzyl p‐phenylazo‐benzyloxycarbonyl‐glycyl‐glycollyl‐glycinate are described. These compounds have been prepared as intermediates for the synthesis of other depsipeptides.
R. Schwyzer, J. P. Carrión
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Marine Depsipeptides as Promising Pharmacotherapeutic Agents

Current Protein & Peptide Science, 2016
Depsipeptides are a group of biologically active peptides that have at least one of the amide bonds replaced by an ester bond. These peptides sometimes present additional chemical modifications, including unusual amino acid residues in their structures.
Marisa, Rangel, Carlos José Correia, de Santana, Andréia, Pinheiro, Lilian, Dos Anjos, Tania, Barth, Osmindo Rodrigues, Pires, Wagner, Fontes, Mariana S, Castro   +7 more
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The structure-antimicrobial relation for valinomycin depsipeptides

Experientia, 1965
Auf Grund eines grossen Vergleichsmaterials wurden die Strukturelemente, die fur die antimikrobielle Aktivitat der Cyclodepsipeptide notig sind, ermittelt. Insbesondere wurden Ringgrosse, Ersatz der Ester- oder N-Methylamid-Gruppe durch eine Amidgruppe, strukturelle und konfigurative Anderung der Aminosaure- und Hydroxysaurereste studiert.
M M, Shemyakin, E I, Vinogradova, M Y, Feigina, N A, Aldanova, N E, Loginova, I D, Ryabova, I A, Pavlenko   +6 more
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Total Synthesis of Antitumor Depsipeptide (−)-Doliculide

Organic Letters, 2001
[reaction: see text] (-)-Doliculide, a potent antitumor agent, is synthesized stereoselectively in a convergent manner. The key strategy involves a stereoselective synthesis of the polyketide unit and synthesis of the D-tyrosine derivative, followed by assembly of the fragments by an esterification and cycloamidation reaction sequence. The synthesis of
A K, Ghosh, C, Liu
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Self‐Assembly of Chiral Depsipeptide Dendrimers

Chemistry – A European Journal, 2006
AbstractThe self‐assembly of chiral depsipeptide dendrons 4, which contain a cyanuric acid building block at their focal point, with the homotritopic Hamilton receptor 1 is reported. The 1:3 compositions of the resulting chiral supramolecular dendrimers, the association constants Kn, and the cooperativity of binding expressed by Scatchard plots and the
Kristine, Hager, Alexander, Franz, Andreas, Hirsch   +2 more
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Depsipeptides Communication 31. Synthesis of depsipeptides containing ?-hydroxy ?-amino acid residues

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1965
Depsipeptides containing α-hydroxy α-amino acid residues as hydroxy-acid component were synthesized.
G. A. Ravdel', N. A. Krit, V. A. Oladkina, L. A. Shchukina, M. M. Shemyakin   +4 more
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Siamese Depsipeptides: Constrained Bicyclic Architectures

Angewandte Chemie, 2009
has been designed. Cyclic depsipeptide dimers connected by a CC bond were constructed. Two kind of possible connections can be envisaged, those that share a side chain bond or those that share a backbone bond. Owing to the resulting proximity of both structurally identical cycles, they can be called Siamese depsipeptides. For Siamese depsipeptides, the
Javier, Ruiz-Rodríguez, Jan, Spengler, Fernando, Albericio   +2 more
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