Results 91 to 100 of about 5,433 (281)
Parkinson's Disease: Leucine-Rich Repeat Kinase 2 and Autophagy, Intimate Enemies
Parkinson's disease is the second common neurodegenerative disorder, after Alzheimer's disease. It is a clinical syndrome characterized by loss of dopamine-generating cells in the substancia nigra, a region of the midbrain.
José M. Bravo-San Pedro +5 more
doaj +1 more source
Proteomic and functional deregulations in Philadelphia negative Myeloproliferative Neoplasms
En plus des anomalies génétiques, plusieurs études ont rapporté des altérations des protéines chez les patients atteintes de Syndromes Myéloprolifératifs (SMP) Ph- qui pourraient participer à leurs phénotypes cliniques.
Socoro Yuste, Nuria
core
Biomarkers of lung congestion and injury in acute heart failure
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
wiley +1 more source
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze +19 more
wiley +1 more source
Structural Reforms and Growth: Product and Labor Market Deregulations
The paper focuses on labor and product market deregulations, as fundamental elements in the passage from an investment to an innovation-based economy. The approach undertaken is prominently empirical.
Eijffinger, Sylvester C W +1 more
core +1 more source
Corporate Taxation and the Size of New Firms: Evidence From Europe
Using a novel country-industry level panel database with information on newly incorporated firms in 17 European countries between 1997 and 2004, we study how taxation of corporate income affects the size of entrants at the country-industry level.
Di Giacomo, M. +2 more
core
Uterine leiomyosarcoma (ULMS) is an aggressive malignancy characterized by marked chemoresistance, frequent relapses, and poor outcome. Despite efforts to improve survival over the past several decades, only minimal advances have been made.
Brewer Savannah, Kari Jo
core
Smart charging with hourly pricing optimizes electric vehicle (EV) charging in developing countries, reducing EV owner costs by 30% and easing grid congestion. Using an agent‐based energy management system, the study shows dynamic pricing effectively shifts charging to off‐peak hours, enhancing grid stability and supporting sustainable EV adoption in ...
Maha Iftikhar +8 more
wiley +1 more source
Managing for resilience with ecological structure: Portfolio effects in the Laurentian Great Lakes
Combined effects of global change, including land conversion, biological invasions, and overexploitation, have degraded the resilience of ecosystems and the services they provide. Here, we identify key ecological structures and processes that can be targeted by management to improve resilience at scales ranging from single species to entire landscapes.
Kayla RS Hale +15 more
wiley +1 more source
Revisiting Swedish Postmodernism : Gendered Architecture and Other Stories
The years around 1980 contained dynamic architectural discourse in Swedish history covering contradictory ideas all sharing the critique of functionalism. Revisiting the discussions today implies a reconsideration of the historiographical self-conception,
Mattsson, Helena,
core +1 more source

