Results 1 to 10 of about 1,794 (242)

Metabolic Deregulations in Patients with Polycystic Ovary Syndrome [PDF]

open access: yesMetabolites, 2023
Polycystic ovary syndrome (PCOS) contributes to endocrine and metabolic complications for women worldwide. The aim of this study was to establish the usefulness of new anthropometric indices and atherogenic indices in the evaluation of metabolic ...
Marzena Jabczyk   +7 more
doaj   +7 more sources

Probiotic: is diet part of the efficacy equation? [PDF]

open access: yesGut Microbes, 2023
Discovered at the beginning of the 20th century by Nobel laureate Élie Metchnikoff, probiotics have more recently emerged as a potential noninvasive therapeutic approach for the treatment of various chronic diseases.
Héloïse Rytter   +2 more
doaj   +2 more sources

Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia

open access: yesGut Microbes, 2021
An array of chronic inflammatory diseases, including metabolic diseases such as obesity and diabetes, are thought to be promoted by disturbance of the intestinal microbiota.
Clara Delaroque   +3 more
doaj   +2 more sources

Cutaneous Melanoma in the Context of Aging [PDF]

open access: yesMedicina
Ageing is sustained by a complex network of cellular and molecular mechanisms. The main mechanisms are cellular senescence, telomere attrition, gene expression changes, metabolic dysregulations, oxidative stress and epigenetic modifications such as DNA ...
Monica Neagu   +2 more
doaj   +2 more sources

Mucus-penetrating microbiota drive chronic low-grade intestinal inflammation and metabolic dysregulation

open access: yesGut Microbes
Metabolic syndrome is, in humans, associated with alterations in the composition and localization of the intestinal microbiota, including encroachment of bacteria within the colon’s inner mucus layer.
Melissa C. Kordahi   +3 more
doaj   +3 more sources

The Effects of Chia Defatted Flour as a Nutritional Supplement in C57BL/6 Mice Fed a Low-Quality Diet [PDF]

open access: yesFoods
Today, consumption of diets rich in saturated fat and fructose, associated with a variety of metabolic deregulations, has increased. The aim of this study was to evaluate the effect of dietary supplementation with a residue of defatted chia seed on a ...
Agustin Lucini Mas   +4 more
doaj   +2 more sources

Perturbation of the circadian clock in chronic diseases involving organ fibrosis [PDF]

open access: yesThe Journal of Clinical Investigation
Chronic organ disease is often complicated by fibrosis, the excessive accumulation of extracellular matrix, as a consequence of dysfunctional wound healing responses.
Atish Mukherji   +3 more
doaj   +2 more sources

Metabolic deregulation in prostate cancer [PDF]

open access: yesMolecular Omics, 2018
Abstract Introduction: The prostate exhibits a unique metabolism that changes during initial neoplasia to aggressive prostate cancer (PCa) and metastasis. The study of PCa metabolism thus represents a new avenue for diagnostics, particularly early diagnosis of aggressive PCa cases.
Sriganesh Srihari   +5 more
openaire   +6 more sources

Metabolic Deregulation in Pulmonary Hypertension

open access: yesCurrent Issues in Molecular Biology, 2023
The high morbidity and mortality rate of pulmonary arterial hypertension (PAH) is partially explained by metabolic deregulation. The present study complements our previous publication in “Genes” by identifying significant increases of the glucose transporter solute carrier family 2 (Slc2a1), beta nerve growth factor (Ngf), and nuclear factor erythroid ...
Rajamma Mathew   +3 more
openaire   +3 more sources

PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction

open access: yesCells, 2023
Aging and obesity are the two prominent driving forces of metabolic dysfunction, yet the common underlying mechanisms remain elusive. PPARγ, a central metabolic regulator and primary drug target combatting insulin resistance, is hyperacetylated in both ...
Ying He   +6 more
doaj   +1 more source

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