Results 61 to 70 of about 1,072,002 (279)

On Derivative Free Multiple-Root Finders with Optimal Fourth Order Convergence

open access: yesMathematics, 2020
A number of optimal order multiple root techniques that require derivative evaluations in the formulas have been proposed in literature. However, derivative-free optimal techniques for multiple roots are seldom obtained.
Janak Raj Sharma   +2 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

On the semilocal convergence of derivative free methods for solving nonlinear equations

open access: yesJournal of Numerical Analysis and Approximation Theory, 2012
We introduce a Derivative Free Method (DFM) for solving nonlinear equations in a Banach space setting. We provide a semilocal convergence analysis for DFM using recurrence relations. Numerical examples validating our theoretical results are also provided
Ioannis K. Argyros, Hongmin Ren
doaj   +2 more sources

On the Cardinality of Positively Linearly Independent Sets

open access: yes, 2015
Positive bases, which play a key role in understanding derivative free optimization methods that use a direct search framework, are positive spanning sets that are positively linearly independent.
Hare, W., Song, H.
core   +1 more source

Sequential Penalty Derivative-Free Methods for Nonlinear Constrained Optimization

open access: yesSIAM Journal on Optimization, 2010
We consider the problem of minimizing a continuously differentiable function of several variables subject to smooth nonlinear constraints. We assume that the first order derivatives of the objective function and of the constraints can be neither calculated nor explicitly approximated.
LIUZZI, Giampaolo   +2 more
openaire   +7 more sources

Model-Based Derivative-Free Methods for Convex-Constrained Optimization

open access: yesSIAM Journal on Optimization, 2022
We present a model-based derivative-free method for optimization subject to general convex constraints, which we assume are unrelaxable and accessed only through a projection operator that is cheap to evaluate. We prove global convergence and a worst-case complexity of $O(ε^{-2})$ iterations and objective evaluations for nonconvex functions, matching ...
Matthew Hough, Lindon Roberts
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Deterministic Policy Optimization by Combining Pathwise and Score Function Estimators for Discrete Action Spaces

open access: yes, 2017
Policy optimization methods have shown great promise in solving complex reinforcement and imitation learning tasks. While model-free methods are broadly applicable, they often require many samples to optimize complex policies. Model-based methods greatly
Ermon, Stefano, Levy, Daniel
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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