Results 61 to 70 of about 87,295 (253)

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

LncRNA-599554 sponges miR-15a-5p to contribute inductive ability of dermal papilla cells through positive regulation of the expression of Wnt3a in cashmere goat

Electronic Journal of Biotechnology, 2020
Background: Long non-coding RNAs (lncRNAs), as post-transcriptional regulators, were thought to function in the inductive property of dermal papilla cells (DPCs) in cashmere goat.
Rong H. Yin, Yan R. Wang, Su J. Zhao, Rong L. Yin, Man Bai, Ze Y. Wang, Yu B. Zhu, Yu Y. Cong, Hai Y. Liu, Wen L. Bai   +9 more
doaj   +1 more source

Comparative secretome analysis of human follicular dermal papilla cells and fibroblasts using shotgun proteomics [PDF]

BMB Reports, 2012
The dermal papilla cells (DPCs) of hair follicles are known tosecrete paracrine factors for follicular cells. Shotgun proteomicanalysis was performed to compare the expression profiles ofthe secretomes of human DPCs and dermal fibroblasts (DFs).In this ...
Chong Hyun Won, Oh Sang Kwon, Yong Jung Kang, Hyeon Gyeong Yoo, Dong Hun Lee, Jin Ho Chung, Kyu Han Kim, Won Seok Park, Nok Hyun Park, Kun Cho, Sang Oh Kwon, Jong-Soon Choi, Hee Chul Eun   +12 more
doaj   +1 more source

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

LncRNA ST6GALNAC3 inhibits dermal fibroblast proliferation and migration in cashmere goat hair follicles via the chi-miR-24-3p/ID4 axis [PDF]

Animal Bioscience
Objective Dermal papilla is developed from the continuous proliferation and differentiation of dermal fibroblasts, which is the key to the normal development of hair follicles.
Rong Ma, Qing Ma, Lu Zhang, Bingjie Ma, Xuxu Bao, Yiming Zhang, Le Wang, Qi Lv, Zhiying Wang, Ruijun Wang, Rui Su, Yanhong Zhao, Fangzheng Shang, Yu Wang, Yanjun Zhang   +14 more
doaj   +1 more source

Immunocytochemical analysis of cultured dermal papilla cells (DPCs).

, 2013
Immunocytochemistry of DPCs using anti-α-SMA antibody (green) was performed (A&B) when cells started to exhibit an aggregative growth behavior, while the other two antibodies were performed on monolayer cultured DPCs.
Xudong Guo (153535), Teng Xu (129595), Dongjun Liu (233547), Jianlong Yuan (460571), Bing Zhu (145649)   +4 more
core   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Multimodal label-free imaging of living dermal equivalents including dermal papilla cells

Stem Cell Research & Therapy, 2018
Background Despite the significant progress in the development of skin equivalents (SEs), the problem of noninvasively assessing the quality of the cell components and the collagen structure of living SEs both before and after transplantation remains ...
Aleksandra V. Meleshina, Olga S. Rogovaya, Varvara V. Dudenkova, Marina A. Sirotkina, Maria M. Lukina, Alena S. Bystrova, Victoria G. Krut, Daria S. Kuznetsova, Ekaterina P. Kalabusheva, Andrey V. Vasiliev, Ekaterina A. Vorotelyak, Elena V. Zagaynova   +11 more
doaj   +1 more source

Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells. [PDF]

PLoS ONE, 2012
Alopecia is the common hair loss problem that can affect many people. However, current therapies for treatment of alopecia are limited by low efficacy and potentially undesirable side effects.
Soung-Hoon Lee, Juyong Yoon, Seung Ho Shin, Muhamad Zahoor, Hyoung Jun Kim, Phil June Park, Won-Seok Park, Do Sik Min, Hyun-Yi Kim, Kang-Yell Choi   +9 more
doaj   +1 more source

K15 & Id3 expression in intact and regenerating adult vibrissae rodent hair follicles [PDF]

, 2009
The hair follicle can renew itself through an intrinsic stem cell population and has the ability to undergo hair follicle growth cycle; its regenerative activities under normal and experimental conditions together with a feature of easy access make it an
Chen, Bo
core