Results 101 to 110 of about 458,423 (305)

Spatial Transcriptional Dynamics of CD74⁺ B Cells in Tertiary Lymphoid Structures Drive Immune Evolution in Penile Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
In penile squamous cell carcinoma, a higher tertiary lymphoid structure score is associated with improved survival. This is mediated by CD74⁺ B cells, which exhibit early developmental plasticity and the ability to differentiate into plasma cells. Functioning as a molecular switch, these cells activate naive T cells via HLA‐DRA–CD4 interaction, thereby
Ting Xue   +16 more
wiley   +1 more source

A Case of Palmoplantar Keratodermas Complicated by Pseudoainhum and Literature Review

open access: yesClinical, Cosmetic and Investigational Dermatology
Junhong Ye,1 Wen Li,1 Xianxu Yang,1 Yanhai Shi,2 Wen Lv3 1Department of Plastic Surgery and Skin Disease, Hainan Fifth People’s Hospital, Haikou City, Hainan Province, People’s Republic of China; 2Department of Skin Disease, Qionghai People’s Hospital ...
Ye J, Li W, Yang X, Shi Y, Lv W
doaj  

Dermatology education in U.S. ophthalmology residency: a survey of the program directors

open access: yesBMC Medical Education
Background Many ocular conditions have associated dermatological findings. However, the inclusion of dermatology education in U.S. Ophthalmology residency programs remains limited.
Winnie Fan   +3 more
doaj   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

open access: yesAdvanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang   +6 more
wiley   +1 more source

Investigating the Impact of Circulating Immune Cells on Acne Using Mendelian Randomization

open access: yesClinical, Cosmetic and Investigational Dermatology
Xudong Wang,1,2,* Shaoyu Guan,3,* Zhikuan Xia,2 Xin Zhang,2 Yu Bai,2 Qiang Li,4 Haitao Li,2 Rongya Yang2 1Southern Medical District of Chinese PLA General Hospital, Beijing, 100843, People’s Republic of China; 2Department of Dermatology ...
Wang X   +7 more
doaj  

Chemical peels in aesthetic dermatology: an update 2009 [PDF]

open access: bronze, 2009
TC Fischer   +4 more
openalex   +1 more source

Unique Aerofoil‐Structured Microfluidics for High Throughput Lipid Nanoparticle Formulation Screening and Scale‐up

open access: yesAdvanced Science, EarlyView.
This study presents aerofoiled microfluidic structures optimized for efficient mixing and lipid nanoparticle (LNP) formation across broad flow rates. Based on this design, two dedicated systems are introduced: MiNANO‐form for high‐throughput formulation screening and MiNANO‐scale for continuous large‐scale production, enabling reproducible, high ...
Dongsheng Liu   +8 more
wiley   +1 more source

Exosomes and Hair Regeneration: A Systematic Review of Clinical Evidence Across Alopecia Types and Exosome Sources

open access: yesClinical, Cosmetic and Investigational Dermatology
Mohammed A Al Ameer,1 Abdulaziz T Alnajim,1 Ali Al Ameer,2 Zainab Alsalman,3 Ghadeer A Al Ameer,4 Sarah T Alnajim,5 Anwar A Alghamdi,1 Raniya Moideen,4 Enas M Al Hadi6 1Department of Dermatology, Aseer Central Hospital, Abha, Saudi Arabia; 2Department of
Al Ameer MA   +8 more
doaj  

A Multicenter Validation of a Fully Automated Chemiluminescence Immunoassay for Plasma Elafin in Psoriasis Diagnosis and Severity Assessment

open access: yesAdvanced Science, EarlyView.
The fully automated CLIA demonstrates high sensitivity and specificity for plasma Elafin, achieving 88% diagnostic accuracy and an AUC of 0.92 for psoriasis detection in a multicenter cohort. The assay reliably distinguishes psoriasis from other dermatoses, objectively stratifies disease severity, and allows longitudinal monitoring, supporting its ...
Jingkun Yi   +8 more
wiley   +1 more source

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