Results 11 to 20 of about 247,793 (398)

Keloid and Hypertrophic Scars Are the Result of Chronic Inflammation in the Reticular Dermis

open access: yesInternational Journal of Molecular Sciences, 2017
Keloids and hypertrophic scars are caused by cutaneous injury and irritation, including trauma, insect bite, burn, surgery, vaccination, skin piercing, acne, folliculitis, chicken pox, and herpes zoster infection.
Rei Ogawa,, Facs
exaly   +2 more sources

Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain

open access: yesScience Robotics, 2018
A multilayered e-dermis allows a prosthesis and an amputee to perceive a range of innocuous and noxious tactile stimuli. The human body is a template for many state-of-the-art prosthetic devices and sensors.
Luke E Osborn   +2 more
exaly   +2 more sources

Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages

open access: yesNature Communications, 2016
Sustained epidermal Wnt/β-catenin signalling expands the stem cell compartment and induces ectopic hair follicles (EFs). This is accompanied by extensive fibroblast proliferation and extracellular matrix (ECM) remodelling in the underlying dermis.
Fiona M Watt
exaly   +2 more sources

Shagreen Patch in Tuberous Sclerosis Complex at High-Frequency Ultrasound [PDF]

open access: yesDiagnostics
We present a case of a 19-year-old female patient with tuberous sclerosis complex and a shagreen patch on her left dorsal region. Decreased echogenicity and increased thickness of the dermis were shown by high-frequency ultrasound.
Corrado Tagliati, Ximena Wortsman
doaj   +2 more sources

Aging in the dermis: Fibroblast senescence and its significance

open access: yesAging Cell, 2023
Skin aging is characterized by changes in its structural, cellular, and molecular components in both the epidermis and dermis. Dermal aging is distinguished by reduced dermal thickness, increased wrinkles, and a sagging appearance.
Jing Zhang   +3 more
semanticscholar   +1 more source

Assessing the Role of Carbonyl Adducts, Particularly Malondialdehyde Adducts, in the Development of Dermis Yellowing Occurring during Skin Photoaging

open access: yesLife, 2022
Solar elastosis is associated with a diffuse yellow hue of the skin. Photoaging is related to lipid peroxidation leading to the formation of carbonyl groups. Protein carbonylation can occur by addition of reactive aldehydes, such as malondialdehyde (MDA),
Hélène Zucchi   +5 more
doaj   +1 more source

Focus on the Contribution of Oxidative Stress in Skin Aging

open access: yesAntioxidants, 2022
Skin aging is one of the most evident signs of human aging. Modification of the skin during the life span is characterized by fine lines and wrinkling, loss of elasticity and volume, laxity, rough-textured appearance, and pallor.
Federica Papaccio   +3 more
doaj   +1 more source

Effect of Roflumilast Cream vs Vehicle Cream on Chronic Plaque Psoriasis: The DERMIS-1 and DERMIS-2 Randomized Clinical Trials.

open access: yesJournal of the American Medical Association (JAMA), 2022
Importance Once-daily roflumilast cream, 0.3%, a potent phosphodiesterase 4 inhibitor, demonstrated efficacy and was well tolerated in a phase 2b trial of patients with psoriasis.
M. Lebwohl   +25 more
semanticscholar   +1 more source

A mechanistic view on the aging human skin through ex vivo layer-by-layer analysis of mechanics and microstructure of facial and mammary dermis

open access: yesScientific Reports, 2022
Age-related changes in skin mechanics have a major impact on the aesthetic perception of skin. The link between skin microstructure and mechanics is crucial for therapeutic and cosmetic applications as it bridges the micro- and the macro-scale. While our
B. Lynch   +6 more
semanticscholar   +1 more source

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