Results 101 to 110 of about 1,183 (137)

Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy. [PDF]

NPJ Vaccines, 2023
Teymournejad O, Li Z, Beesetty P, Yang C, Montgomery CP.   +4 more
europepmc   +1 more source

Targeting Key Enzymatic Snake Venom Proteins Using Repurposed Small Molecule Inhibitors: Emerging Adjuncts to Antivenom Therapy. [PDF]

Int J Mol Sci
Reghu N, Kiruthika S, Santhosh AK, Narayanan AL, Geetha KG, Sidheek N, Danthuluri SS, Nair BG, Vanuopadath M.   +8 more
europepmc   +1 more source

A single amino acid substitution in Fibronectin Binding protein A (FnBPA) governs Staphylococcus aureus virulence via host transglutaminase-mediated fibrin crosslinking. [PDF]

PLoS Pathog
Motta C, Turley M, Barbieri G, Famà A, Coppolino F, Bellan Menegussi E, Geoghegan JA, Beninati C, Pellegrini A, Pietrocola G.   +9 more
europepmc   +1 more source

Advancements of mRNA-lipid nanoparticle links to gene editing and immune responses. [PDF]

J Genet Eng Biotechnol
Sundaram K, Prabhu V.
europepmc   +1 more source

Dermonecrosis caused by spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib

, 2023
Bartlett KE, Hall SR, Rasmussen SA, Crittenden E, Dawson CA, Albulescu L, Laprade W, Harrison RA, Saviola AJ, Modahl CM, Jenkins TP, Wilkinson MC, Gutiérrez JM, Casewell NR.   +13 more
europepmc   +1 more source

Large animal models for the assessment of snakebite envenoming therapies. [PDF]

NPJ Drug Discov
Benard-Valle M, Ahmadi S, Modahl CM, Neri-Castro E, Alagón A, Boyer L, Ljungars A, Laustsen AH.   +7 more
europepmc   +1 more source

A Case of Cobra Bite Complicated with Basilar Artery Occlusion.

J Emerg Trauma Shock, 2023
Yahaya SNB, Khan AHKY, Sankala HA.
europepmc   +1 more source

Identification of an antibiotic from an HTS targeting EF-Tu:tRNA interaction: a prospective topical treatment for MRSA skin infections. [PDF]

Appl Environ Microbiol
Mandecki W, Chudaev M, Ye W, Wang AQ, Wilson KJ, Xu X, Kim J, Parker D, Alland D, Kumar P, Li B, Yang JH, Kreiswirth B, Mediavilla JR, Marugan JJ, Henderson MJ, Goldman E.   +16 more
europepmc   +1 more source

In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection. [PDF]

Mol Ther
Tkaczyk C, Newton M, Patnaik MM, Thom G, Strain M, Gamson A, Daramola O, Murthy A, Douthwaite J, Stepanov O, Boger E, Yang H, Esser MT, Lidwell A, DiGiandomenico A, Santos L, Sellman BR.   +16 more
europepmc   +1 more source

Enhanced Staphylococcus aureus protection by uncoupling of the α-toxin-ADAM10 interaction during murine neonatal vaccination. [PDF]

Nat Commun
Tomaszewski KL, Blanchard M, Olaniyi R, Brenton HR, Hayes S, Fatma F, Amarasinghe GK, Cho BK, Goo YA, DeDent AC, Fritz SA, Wardenburg JB.   +11 more
europepmc   +1 more source