Results 61 to 70 of about 1,740 (174)
Insights into brown spider and loxoscelism [PDF]
Invertebrate Survival Journal, 2005 Loxosceles is a genus of cosmopolitan spiders comprising several species, and popularly known as brown spiders or brown recluses. Brown spider bites can cause dermonecrotic lesions and systemic reactions known as loxoscelism.
M H Appel +3 more
doaj +1 more source
Sphingomyelinase D Activity in Sicarius tropicus Venom : Toxic Potential and Clues to the Evolution of SMases D in the Sicariidae Family [PDF]
, 2021 The spider family Sicariidae includes three genera, Hexophthalma, Sicarius and Loxosceles. The three genera share a common characteristic in their venoms: the presence of Sphingomyelinases D (SMase D).
Bertani, Rogerio +4 more
core +1 more source
Identification and validation of a linear protective neutralizing epitope in the β-pore domain of alpha toxin. [PDF]
PLoS ONE, 2015 The plethora of virulence factors associated with Staphylococcus aureus make this bacterium an attractive candidate for a molecularly-designed epitope-focused vaccine.
Jon Oscherwitz, Kemp B Cease
doaj +1 more source
Phospholipase D toxins of brown spider venom convert lysophosphatidylcholine and sphingomyelin to cyclic phosphates. [PDF]
PLoS ONE, 2013 Venoms of brown spiders in the genus Loxosceles contain phospholipase D enzyme toxins that can cause severe dermonecrosis and even death in humans.
Daniel M Lajoie +5 more
doaj +1 more source
Journal of Venomous Animals and Toxins including Tropical Diseases, 2012 Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus.
NB Pereira +9 more
doaj +1 more source
, 2017 Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J +5 more
core +3 more sources
Loxoscelism: Cutaneous and Hematologic Manifestations
Advances in Hematology, Volume 2019, Issue 1, 2019., 2019 Background. Brown recluse spider (BRS) envenomation can lead to significant morbidity through severe local reaction and systemic illness including acute hemolytic anemia, rhabdomyolysis, disseminated intravascular coagulopathy (DIC), and even death. We aim to describe the clinical features and the roles of antibiotics and steroids in the treatment of ...
Ngan Nguyen +2 more
wiley +1 more source
Journal of Immunology Research, Volume 2019, Issue 1, 2019., 2019 Worldwide, an estimated 12 million people are infected with Leishmania spp. and an additional 350 million are at risk of infection. Leishmania are intracellular parasites that cause disease by suppressing macrophage microbicidal responses. Infection can remain asymptomatic or lead to a spectrum of diseases including cutaneous, mucocutaneous, and ...
Ryan D. Lockard +3 more
wiley +1 more source
Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018 Bothrops lanceolatus snake venom causes systemic thrombotic syndrome but also local inflammation involving extensive oedema, pain, and haemorrhage. Systemic thrombotic syndrome may lead to fatal pulmonary embolism and myocardial and cerebral infarction. Here, we investigated the ability of B.
Marie Delafontaine +7 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2017 Snakebites are a serious problem in public health due to their high morbimortality. Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims. The available specific treatment is the antivenom serum therapy, whose effectiveness is reduced against these effects.
Juliana Félix-Silva +4 more
wiley +1 more source