Results 51 to 60 of about 1,183 (137)
Highlights in the knowledge of brown spider toxins
Journal of Venomous Animals and Toxins including Tropical Diseases, 2017 Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function.
Daniele Chaves-Moreira +5 more
doaj +1 more source
Toxins, 2023 Envenomation caused by venomous animals may trigger significant local complications such as pain, edema, localized hemorrhage, and tissue necrosis, in addition to complications such as dermonecrosis, myonecrosis, and even amputations.
Érica S. Carvalho +14 more
doaj +1 more source
Animal Models and Experimental Medicine, Volume 8, Issue 1, Page 20-29, January 2025.Xenograft‐bearing immunodeficient mice are susceptible to developing unwanted disorders primarily irrelevant to nature of the xenografted tumor; and if get involved with such disorders, they do not produce reliable results, inevitably confounding the research outputs.
Seyed Mostafa Monzavi +4 more
wiley +1 more source
BioMed Research International, Volume 2013, Issue 1, 2013., 2013 Bothrops asper (Squamata: Viperidae) is the most important venomous snake in Central America, being responsible for the majority of snakebite accidents. Four basic PLA2s (pMTX‐I to ‐IV) were purified from crude venom by a single‐step chromatography using a CM‐Sepharose ion‐exchange column (1.5 × 15 cm).
Aristides Quintero Rueda +8 more
wiley +1 more source
Immunology &Cell Biology, Volume 102, Issue 5, Page 365-380, May‐June 2024.This study demonstrates that three secreted immune evasion factors from the staphylococcal superantigen‐like (SSL) protein family—SSL3, 7 and 11—can be successfully fused into a polyprotein. Mice immunized with a functionally inactive version of the polyprotein in the squalene‐based adjuvant (AddaVax), but not the equivalent amount of the individual ...
Janlin Ying Hui Chan +5 more
wiley +1 more source
Platelet participation in the pathogenesis of dermonecrosis induced by Loxosceles gaucho venom [PDF]
, 2015 Loxosceles gaucho spider venom induces in vitro platelet activation and marked thrombocytopenia in rabbits. Herein, we investigated the involvement of platelets in the development of the dermonecrosis induced by L.
Tavares, F. L. +6 more
core +1 more source
Staphylococcus aureus alpha toxin suppresses effective innate and adaptive immune responses in a murine dermonecrosis model. [PDF]
PLoS ONE, 2013 An optimal host response against Staphylococcus aureus skin and soft tissue infections (SSTI) is dependent on IL-1β and IL-17 mediated abscess formation.
Christine Tkaczyk +11 more
doaj +1 more source
Toxins, 2022 Bites of Loxosceles spiders can lead to a set of clinical manifestations called loxoscelism, and are considered a public health problem in many regions. The signs and symptoms of loxoscelism are divided into cutaneous and systemic forms.
Luiza Helena Gremski +7 more
doaj +1 more source
Toxins, 2021 Bites by many Asiatic and African cobras (Genus: Naja) cause severe local dermonecrosis and myonecrosis, resulting in permanent disabilities. We studied the time scale in which two Indian polyvalent antivenoms, VINS and Bharat, remain capable of ...
Umesha Madhushani +4 more
doaj +1 more source
Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates
Toxins, 2023 Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
doaj +1 more source