Results 71 to 80 of about 1,746 (180)

Biotechnological potential of Phospholipase D for Loxosceles antivenom development [PDF]

open access: yes, 2020
Loxoscelism is one of the most important forms of araneism in South America. The Health Authorities from countries with the highest incidence and longer history in registering loxoscelism cases indicate that specific antivenom should be administered ...
Cascone, Osvaldo   +3 more
core   +1 more source

Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2017
Snakebites are a serious problem in public health due to their high morbimortality. Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims. The available specific treatment is the antivenom serum therapy, whose effectiveness is reduced against these effects.
Juliana Félix-Silva   +4 more
wiley   +1 more source

Reproductive Pathological Changes Associated with Experimental Subchronic Corynebacterium pseudotuberculosis Infection in Nonpregnant Boer Does

open access: yesJournal of Pathogens, Volume 2016, Issue 1, 2016., 2016
Corynebacterium pseudotuberculosis causes caseous lymphadenitis (CLA), which is a contagious and chronic disease in sheep and goats. In order to assess the histopathological changes observed in the reproductive organs of nonpregnant does infected with the bacteria, 20 apparently healthy adult Boer does were divided into four inoculation groups ...
A. M. Othman   +8 more
wiley   +1 more source

The calcium-dependent protease of Loxosceles gaucho venom acts preferentially upon red cell band 3 transmembrane protein

open access: yesBrazilian Journal of Medical and Biological Research, 2003
Eighty micrograms red blood cell (RBC) ghosts from patients who had previously exhibited the cutaneous form of loxoscelism (presenting localized dermonecrosis) and the viscerocutaneous form of loxoscelism (presenting dermonecrosis, hemoglobinuria ...
O.C. de O. Barretto   +3 more
doaj   +1 more source

Pathogenesis of Intradermal Staphylococcal Infections Rabbit Experimental Approach to Natural Staphylococcus aureus Skin Infections [PDF]

open access: yes, 2020
[EN] Despite the enormous efforts made to achieve effective tools that fight against Staphylococcus aureus, the results have not been successful. This failure may be due to the absence of truly representative experimental models.
Arnau-Bonachera, Alberto   +10 more
core   +1 more source

Biochemical and Functional Characterization of Parawixia bistriata Spider Venom with Potential Proteolytic and Larvicidal Activities

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
Toxins purified from the venom of spiders have high potential to be studied pharmacologically and biochemically. These biomolecules may have biotechnological and therapeutic applications. This study aimed to evaluate the protein content of Parawixia bistriata venom and functionally characterize its proteins that have potential for biotechnological ...
Gizeli S. Gimenez   +13 more
wiley   +1 more source

Multidrug resistant (or antimicrobial-resistant) pathogens - alternatives to new antibiotics? [PDF]

open access: yes, 2017
For the last few decades, multidrug resistance has become an increasing concern for both Gram-positive and Gram-negative bacteria. The number of new molecules has dramatically decreased and antibiotic resistance is now a priority in the international ...
Brunel, A.S., Guery, B.
core   +1 more source

Alkylation of Histidine Residues of Bothrops jararacussu Venom Proteins and Isolated Phospholipases A2: A Biotechnological Tool to Improve the Production of Antibodies

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
Crude venom of Bothrops jararacussu and isolated phospholipases A2 (PLA2) of this toxin (BthTX‐I and BthTX‐II) were chemically modified (alkylation) by p‐bromophenacyl bromide (BPB) in order to study antibody production capacity in function of the structure‐function relationship of these substances (crude venom and PLA2 native and alkylated).
C. L. S. Guimarães   +17 more
wiley   +1 more source

Prospecting Local Treatments Used in Conjunction with Antivenom Administration Following Envenomation Caused by Animals: A Systematic Review

open access: yesToxins, 2023
Envenomation caused by venomous animals may trigger significant local complications such as pain, edema, localized hemorrhage, and tissue necrosis, in addition to complications such as dermonecrosis, myonecrosis, and even amputations.
Érica S. Carvalho   +14 more
doaj   +1 more source

Unwanted disorders and xenogeneic graft‐versus‐host disease in experimental immunodeficient mice: How to evaluate and how to report

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 1, Page 20-29, January 2025.
Xenograft‐bearing immunodeficient mice are susceptible to developing unwanted disorders primarily irrelevant to nature of the xenografted tumor; and if get involved with such disorders, they do not produce reliable results, inevitably confounding the research outputs.
Seyed Mostafa Monzavi   +4 more
wiley   +1 more source

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